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39
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In vivo genome-editing therapy for Duchenne muscular dystrophy: Preclinical studies and first-in-human trial.
(linkinghub.elsevier.com)
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Li G
…
Wang J
Cell
2026-10-26
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#gene therapy
#crispr
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#aav
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32
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Finding MES: A hidden cell state in neuroblastoma.
(linkinghub.elsevier.com)
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Hayes MN
…
Irwin MS
Cancer Cell
2026-10-26
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#transcriptomics
#neuroblastoma
#proteomics
#single-cell
#heterogeneity
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30
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Neoadjuvant durvalumab plus chemotherapy in resectable or borderline resectable non-small-cell lung cancer: the phase 2 MDT-BRIDGE trial.
(nature.com)
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Reck M
…
Spicer J
Nature Medicine
2026-10-26
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#immunotherapy
#neoadjuvant
#lung cancer
#chemotherapy
#clinical trial
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28
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UBT251, a novel triple GLP-1, GIP, and glucagon receptor agonist, in adults with type 2 diabetes: A multicenter, randomized phase 2 trial.
(linkinghub.elsevier.com)
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Zhou Z
…
Yan H
Cell Metabolism
2026-10-26
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#diabetes
#pharmacology
#clinical trial
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23
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Human brain cellular xenografts in neuroimmunology and beyond.
(linkinghub.elsevier.com)
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Fattorelli N
…
Mancuso R
Immunity
2026-10-26
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#xenograft
#neuroimmunology
#organoid
#neurodegeneration
#microglia
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23
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A microbiome-reactive TMIGD2(hi) Th17 subset is spatially enriched at the intestinal epithelium and expanded in inflammatory bowel disease.
(linkinghub.elsevier.com)
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Pedersen TK
…
Graham DB
Immunity
2026-10-26
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#microbiome
#immunology
#ibd
#th17
#tolerance
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23
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Single-cell landscape of human adipose tissue reveals THBS1 as a potential driver of fibro-inflammation in metabolic disease.
(nature.com)
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Jung J
…
Choi SH
Nature Communications
2026-10-27
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#transcriptomics
#adipose
#inflammation
#diabetes
#fibrosis
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22
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Sacituzumab Tirumotecan plus Pembrolizumab in PD-L1-Negative Advanced NSCLC.
(nejm.org)
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Zhou F
…
Zhou C
New England Journal of Medicine
2026-10-25
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#immunotherapy
#nsclc
#clinical trial
#oncology
#checkpoint inhibitor
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22
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Divarasib as Compared with Sotorasib or Adagrasib in KRAS G12C-Mutated NSCLC.
(nejm.org)
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Skoulidis F
…
Solomon BJ
New England Journal of Medicine
2026-10-25
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#oncology
#nsclc
#clinical trial
#mutation
#immunotherapy
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22
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Osimertinib-Savolitinib in Advanced NSCLC after Progression during EGFR-TKI Therapy.
(nejm.org)
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Lu S
…
Okuma Y
New England Journal of Medicine
2026-10-25
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#nsclc
#pharmacotherapy
#kinase inhibitor
#amr
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21
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Continuous mass photometry by single-molecule trapping.
(nature.com)
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Loewenthal D
…
Kukura P
Nature Methods
2026-10-26
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#single-molecule
#mass spectrometry
#biophysics
#proteomics
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21
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Tumor digital twins uncover therapeutic strategies in triple-negative breast cancer.
(linkinghub.elsevier.com)
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Victori P
…
Fisher J
Cell Reports Medicine
2026-10-28
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#oncology
#precision medicine
#modeling
#biomarker
#drug resistance
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21
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HGVD: Human Genetic Variation Database update 2026 with sequencing of 4344 genetically diverse Japanese individuals.
(academic.oup.com)
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Murakami Y
…
Higasa K
Nucleic Acids Research
2026-10-27
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#sequencing
#population-genetics
#algorithm
#databases
#genomics
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21
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KEGG for characterizing genomes and pathways in the biosphere.
(academic.oup.com)
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Kanehisa M
…
Ishiguro-Watanabe M
Nucleic Acids Research
2026-10-27
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#pathway
#metagenomics
#microbiome
#orthology
#annotation
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21
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ArthroVerse: mapping protein family diversity across arthropod-associated microbiomes.
(academic.oup.com)
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Chasapi IN
…
Pavlopoulos GA
Nucleic Acids Research
2026-10-27
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#metagenomics
#microbiome
#proteomics
#arthropods
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21
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SynBioFooDB: a comprehensive resource for synthetic biology-driven food biomanufacturing.
(academic.oup.com)
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Wei F
…
Ma H
Nucleic Acids Research
2026-10-27
|
#synthetic biology
#metabolic-engineering
#biomanufacturing
#biosynthesis
#database
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21
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SureChEMBL in 2026: an open database of chemical and biomedical annotations from the patent literature.
(academic.oup.com)
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Bosc N
…
O'Boyle NM
Nucleic Acids Research
2026-10-27
|
#chemoinformatics
#drug discovery
#database
#annotation
#biomedical informatics
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21
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VarNexus: an integrative database for interpreting disease-associated regulatory variants through multimodal predictions and functional evidence.
(academic.oup.com)
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Gong L
…
Ding R
Nucleic Acids Research
2026-10-27
|
#variants
#genome-wide association
#regulatory
#qtl
#database
|
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21
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Cell3D: a comprehensive database for interactive 3D visualization and crosstalk analysis of single-cell and spatial omics.
(academic.oup.com)
|
Liu Q
…
Guo Q
Nucleic Acids Research
2026-10-27
|
#transcriptomics
#single-cell
#visualization
#integration
|
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21
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|
Omni-ARMD: an integrated genomic and clinical knowledgebase bridging clinical phenotypes and molecular determinants of antimicrobial resistance.
(academic.oup.com)
|
Tang H
…
Li W
Nucleic Acids Research
2026-10-27
|
#amr
#genomics
#genotype-phenotype
#knowledgebase
#susceptibility
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