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47 ℹ Taurine lowers inflammaging by regulating the NLRP3 inflammasome in macrophages. (linkinghub.elsevier.com) robot Guan C … Dixit VD Cell 2026-10-23 #inflammaging #pyroptosis #immunometabolism #inflammation #macrophage
47 ℹ Cell-state-specific metabolic networks govern ferroptosis versus apoptosis in small cell lung cancer. (linkinghub.elsevier.com) robot Kim JW … Sage J Cell 2026-10-23 #ferroptosis #metabolomics #lung cancer #transcriptomics #apoptosis
47 ℹ Perforin triggers iron-induced mitochondrial damage to drive ferroptosis and anti-tumor immunity. (linkinghub.elsevier.com) robot Bell HN … Zou W Cell 2026-10-23 #ferroptosis #immunity #cancer #cytotoxicity #iron
37 ℹ Molecular functions, cellular responses and pathological implications of the RNA modification N(6)-methyladenosine. (nature.com) robot Kang Z … Liu J Nature Reviews Molecular Cell Biology 2026-10-22 #epigenomics #cancer #methylation #immunity #neurodegeneration
35 ℹ Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic cancer: the randomized phase 2 AMPLIFY-7P trial. (nature.com) robot George B … O'Reilly EM Nature Medicine 2026-10-23 #immunotherapy #pancreatic cancer #vaccination #clinical trial #immunogenicity
35 ℹ Bispecific dual T cell agonist invikafusp alfa in solid tumors: the phase 1/2 START-001 trial. (nature.com) robot Sullivan RJ … Gulley JL Nature Medicine 2026-10-23 #immunotherapy #cancer #clinical trial #antibody #t cell
35 ℹ Determinants of response to CAR T cell therapy in a multicenter, multi-trial cohort analysis of patients with lymphoma. (nature.com) robot Budka J … Bedognetti D Nature Medicine 2026-10-23 #immunotherapy #lymphoma #car-t #biomarker #phenotyping
35 ℹ Interim Analysis of a Phase 3 Trial of Povetacicept in IgA Nephropathy. (nejm.org) robot Barratt J … Lafayette R New England Journal of Medicine 2026-10-23 #immunotherapy #nephropathy #clinical trial #b-cells #autoimmunity
35 ℹ Ravulizumab in IgA Nephropathy - Interim Analysis of a Phase 3 Trial. (nejm.org) robot Barratt J … Lafayette RA New England Journal of Medicine 2026-10-23 #iga-nephropathy #complement-inhibition #glomerulonephritis #clinical trial #proteinuria
35 ℹ Lifestyle-induced regulatory T cell fragility primes adverse events after immune checkpoint blockade. (linkinghub.elsevier.com) robot Patra D … Overacre-Delgoffe AE Cell 2026-10-22 #immunotherapy #microbiome #adverse events #regulatory t cells #dysbiosis
35 ℹ MCT6 is an intestinal Lac-Phe exporter required for metformin-associated weight loss. (linkinghub.elsevier.com) robot Xiao S … Long JZ Cell 2026-10-22 #metabolism #transporter #obesity #intestinal #metformin
35 ℹ Metazoan lagging-strand DNA synthesis is distributive. (linkinghub.elsevier.com) robot Lynch LD … Chistol G Cell 2026-10-22 #replication #single-molecule #dna polymerase #eukaryotes
34 ℹ Dynamic force sensing by bone delays aging and extends lifespan. (linkinghub.elsevier.com) robot Zhang Z … Bai X Cell Metabolism 2026-10-23 #mechanotransduction #aging #bone #immunosenescence #osteocytes
31 ℹ Efficacy and safety of mitapivat in patients with sickle cell disease (RISE UP): a phase 3, double-blind, global, randomised, placebo-controlled trial. (linkinghub.elsevier.com) robot Andemariam B … Abboud MR The Lancet 2026-10-24 #sickle cell disease #clinical trial #hemolytic anemia #pharmacotherapy #vaso-occlusion
28 ℹ Multiomic characterization of microsatellite-stable colorectal cancer reveals distinct biology and targetable vulnerabilities. (linkinghub.elsevier.com) robot Sadanandam A … Byrne AT Cancer Cell 2026-10-22 #colorectal cancer #multiomic #transcriptomics #therapeutics #proteomics
28 ℹ How far are we from multi-omics states to therapeutic targets in microsatellite-stable colorectal cancer? (linkinghub.elsevier.com) robot Chen YX … Wang F Cancer Cell 2026-10-22 #colorectal cancer #multi-omics #precision-oncology #therapeutic targets #proteomics
28 ℹ Lung neuroendocrine cancer induces immunosuppressive macrophages via serotonin to drive resistance to the T cell engager tarlatamab. (linkinghub.elsevier.com) robot Nomura K … Nishikawa H Cancer Cell 2026-10-22 #immunotherapy #macrophage #neuroendocrine #lung cancer #immunosuppression
28 ℹ The neoantigen quality model: Is closer to self more non-self? (linkinghub.elsevier.com) robot Balachandran VP … Greenbaum BD Cancer Cell 2026-10-22 #immunology #neoantigens #t-cell-recognition #cancer #immunity
27 ℹ NF-kappaB phosphorylation controls enhancer selection to shape the inflammatory gene program. (linkinghub.elsevier.com) robot Leao FB … Ghosh S Immunity 2026-10-23 #inflammation #transcriptomics #immunity #chromatin #phosphorylation
26 ℹ Helicobacter pylori Infection - Advances, Challenges, and the Road Ahead. (nejm.org) robot Li H … Marshall BJ New England Journal of Medicine 2026-10-22 #infection #gastric cancer #amr #pathogenesis #vaccination