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47
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In vivo genome-editing therapy for Duchenne muscular dystrophy: Preclinical studies and first-in-human trial.
(linkinghub.elsevier.com)
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Li G
…
Wang J
Cell
2026-10-26
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#gene therapy
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38
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Finding MES: A hidden cell state in neuroblastoma.
(linkinghub.elsevier.com)
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Hayes MN
…
Irwin MS
Cancer Cell
2026-10-26
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#transcriptomics
#neuroblastoma
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#heterogeneity
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35
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Neoadjuvant durvalumab plus chemotherapy in resectable or borderline resectable non-small-cell lung cancer: the phase 2 MDT-BRIDGE trial.
(nature.com)
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Reck M
…
Spicer J
Nature Medicine
2026-10-26
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#immunotherapy
#neoadjuvant
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34
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UBT251, a novel triple GLP-1, GIP, and glucagon receptor agonist, in adults with type 2 diabetes: A multicenter, randomized phase 2 trial.
(linkinghub.elsevier.com)
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Zhou Z
…
Yan H
Cell Metabolism
2026-10-26
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#diabetes
#pharmacology
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27
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Human brain cellular xenografts in neuroimmunology and beyond.
(linkinghub.elsevier.com)
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Fattorelli N
…
Mancuso R
Immunity
2026-10-26
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#xenograft
#neuroimmunology
#organoid
#neurodegeneration
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27
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A microbiome-reactive TMIGD2(hi) Th17 subset is spatially enriched at the intestinal epithelium and expanded in inflammatory bowel disease.
(linkinghub.elsevier.com)
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Pedersen TK
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Graham DB
Immunity
2026-10-26
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#microbiome
#immunology
#ibd
#th17
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27
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Single-cell landscape of human adipose tissue reveals THBS1 as a potential driver of fibro-inflammation in metabolic disease.
(nature.com)
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Jung J
…
Choi SH
Nature Communications
2026-10-27
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#transcriptomics
#inflammation
#adipose
#diabetes
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26
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Osimertinib-Savolitinib in Advanced NSCLC after Progression during EGFR-TKI Therapy.
(nejm.org)
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Lu S
…
Okuma Y
New England Journal of Medicine
2026-10-25
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#nsclc
#pharmacotherapy
#kinase inhibitor
#amr
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26
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Divarasib as Compared with Sotorasib or Adagrasib in KRAS G12C-Mutated NSCLC.
(nejm.org)
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Skoulidis F
…
Solomon BJ
New England Journal of Medicine
2026-10-25
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#oncology
#nsclc
#clinical trial
#mutation
#immunotherapy
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26
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Sacituzumab Tirumotecan plus Pembrolizumab in PD-L1-Negative Advanced NSCLC.
(nejm.org)
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Zhou F
…
Zhou C
New England Journal of Medicine
2026-10-25
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#immunotherapy
#nsclc
#clinical trial
#oncology
#checkpoint inhibitor
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25
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Continuous mass photometry by single-molecule trapping.
(nature.com)
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Loewenthal D
…
Kukura P
Nature Methods
2026-10-26
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#single-molecule
#mass spectrometry
#biophysics
#proteomics
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25
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Tumor digital twins uncover therapeutic strategies in triple-negative breast cancer.
(linkinghub.elsevier.com)
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Victori P
…
Fisher J
Cell Reports Medicine
2026-10-28
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#precision medicine
#oncology
#modeling
#biomarker
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25
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ArthroVerse: mapping protein family diversity across arthropod-associated microbiomes.
(academic.oup.com)
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Chasapi IN
…
Pavlopoulos GA
Nucleic Acids Research
2026-10-27
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#microbiome
#metagenomics
#proteomics
#arthropods
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25
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SynBioFooDB: a comprehensive resource for synthetic biology-driven food biomanufacturing.
(academic.oup.com)
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Wei F
…
Ma H
Nucleic Acids Research
2026-10-27
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#synthetic biology
#biomanufacturing
#metabolic-engineering
#biosynthesis
#database
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25
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PED in 2027: integrating experimental and predicted protein conformational ensembles at scale.
(academic.oup.com)
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Monzon AM
…
Tosatto SCE
Nucleic Acids Research
2026-10-27
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#intrinsically disordered proteins
#proteomics
#structural biology
#computational prediction
#database
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25
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Rice Expression Database (RED) 2.0: an updated rice database integrating diverse RNA expression profiles based on the telomere-to-telomere reference genome.
(academic.oup.com)
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Wang Z
…
Xu T
Nucleic Acids Research
2026-10-27
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#transcriptomics
#gene expression
#rna-seq
#database
#plants
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25
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OSCAR: an omics atlas of paired single-cell ATAC-seq and RNA-seq for decoding cell-specific gene regulation.
(academic.oup.com)
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Song C
…
Wang Q
Nucleic Acids Research
2026-10-27
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#single-cell
#transcriptomics
#chromatin
#gene regulation
#epigenomics
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25
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OmniVira: a knowledgebase of source-linked evidence on viral spillover and cross-species transmission.
(academic.oup.com)
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Zhao P
…
Wu Z
Nucleic Acids Research
2026-10-27
|
#zoonosis
#spillover
#knowledgebase
#virology
#curation
|
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25
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|
CellMarker 3.0: an updated resource of manually curated and computationally predicted cell markers in human/mouse and interactive web tools for single-cell and spatial transcriptomics analysis.
(academic.oup.com)
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Hu C
…
Zhang Y
Nucleic Acids Research
2026-10-27
|
#transcriptomics
#cell-types
#biomarker
#spatial analysis
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25
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VarNexus: an integrative database for interpreting disease-associated regulatory variants through multimodal predictions and functional evidence.
(academic.oup.com)
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Gong L
…
Ding R
Nucleic Acids Research
2026-10-27
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#variants
#genome-wide association
#regulatory
#qtl
#database
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