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25
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The future of early endpoints for neoadjuvant therapy.
(linkinghub.elsevier.com)
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Yau C
…
Esserman LJ
Cancer Cell
2026-11-06
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#cancer
#neoadjuvant
#biomarker
#immunotherapy
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24
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A gait foundation model for prediction of multisystem health phenotypes from 3D skeletal motion.
(nature.com)
|
Gabet A
…
Segal E
Nature Medicine
2026-11-06
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#gait
#phenotyping
#deep learning
#biomarker
#kinematics
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22
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Bacteroides uniformis-generated ornithine alleviates alcohol-associated liver disease via Sirt4-mediated mitochondrial regulation.
(tandfonline.com)
|
Shu H
…
Xu L
Gut Microbes
2026-11-08
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#microbiome
#metabolomics
#liver disease
#mitochondrial
#dysbiosis
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22
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Gut microbiome depletion aggravates glial-mediated Alzheimer's disease pathology through inflammatory, metabolic, and proteostatic dysregulation.
(tandfonline.com)
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Madamanchi K
…
Melkani G
Gut Microbes
2026-11-08
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#microbiome
#neuroinflammation
#neurodegeneration
#proteostasis
#gut-brain axis
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22
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Colonoscopy-based Clostridioides difficile screening for inflammatory bowel disease patients.
(tandfonline.com)
|
Allegretti JR
…
Bry L
Gut Microbes
2026-11-08
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#c. difficile
#ibd
#screening
#colonization
#sequencing
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21
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Cangrelor versus crushed ticagrelor in acute myocardial infarction complicated by cardiogenic shock (DAPT-SHOCK-AMI): a randomised, double-blind trial.
(linkinghub.elsevier.com)
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Motovska Z
…
Bhatt DL
The Lancet
2026-11-07
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#myocardial infarction
#cardiogenic shock
#antiplatelet
#thrombosis
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20
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|
Opposing microbiome-mediated axes link modifiable lifestyles to health and chronic diseases.
(nature.com)
|
Nagata N
…
Uemura N
Nature Medicine
2026-11-05
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#microbiome
#metagenomics
#lifestyle
#mediation
#metabolism
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19
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The contextual pathogenicity of Porphyromonas gingivalis.
(nature.com)
|
Lamont RJ
…
Hajishengallis G
Nature Reviews Microbiology
2026-11-05
|
#virulence
#periodontitis
#microbiome
#dysbiosis
#immunity
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18
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Mapping Future Energy Journeys Through Modeling the Global Transport of Synthetic Energy Carriers.
(nature.com)
|
Langenmayr U
…
Fichtner W
Nature Communications
2026-11-07
|
#modeling
#energy
#hydrogen
#infrastructure
#optimization
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18
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|
Digital readiness for cardiovascular care in high-burden US communities with cardiology workforce constraints.
(nature.com)
|
Perera S
…
Khera R
Nature Medicine
2026-11-05
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#telemedicine
#cardiovascular
#workforce
#disparities
#infrastructure
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18
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|
Intravenous Thrombolysis for Acute Ischemic Stroke - New Directions.
(nejm.org)
|
Grotta JC
New England Journal of Medicine
2026-11-05
|
#stroke
#thrombolysis
#thrombectomy
#ischemia
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18
|
|
Plozasiran for Severe Hypertriglyceridemia and Risk of Pancreatitis.
(nejm.org)
|
Watts GF
…
Gaudet D
New England Journal of Medicine
2026-11-05
|
#hypertriglyceridemia
#pancreatitis
#clinical trial
#rnai
#lipid
|
|
17
|
|
CRISPR mutagenesis of the MYC locus reveals a druggable ultraconserved RNA element.
(linkinghub.elsevier.com)
|
Shi P
…
Wu X
Cell
2026-11-04
|
#crispr
#oncology
#noncoding-rna
#mutagenesis
#therapeutics
|
|
16
|
|
beta-glucan mitigates necrotizing enterocolitis-induced long-term cognitive impairment by remodeling gut microbiota and restoring tryptophan metabolite IAA-mediated gut-brain signaling.
(tandfonline.com)
|
Zhang X
…
Shi Y
Gut Microbes
2026-11-07
|
#microbiome
#gut-brain axis
#enterocolitis
#metabolomics
#neuroinflammation
|
|
16
|
|
gutDBase: a comprehensive database for uncovering heterogeneous molecular characteristics of 15 gut-related diseases.
(academic.oup.com)
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He G
…
Cheng L
Nucleic Acids Research
2026-11-06
|
#transcriptomics
#microbiome
#database
#gastrointestinal
#heterogeneity
|
|
15
|
|
In Vivo CRISPR Base Editing of ANGPTL3 for Durable Lipid Lowering.
(nature.com)
|
Mizoguchi T
…
Khera AV
Nature
2026-11-06
|
#crispr
#genome editing
#hyperlipidemia
#cardiovascular
#therapeutics
|
|
14
|
|
Neural interface instructs layer 4-appropriate circuit reconstruction with engrafted human brain organoids and improves visually guided behavior.
(linkinghub.elsevier.com)
|
Chang ZH
…
Li XH
Cell Stem Cell
2026-11-06
|
#neurorepair
#organoid
#neuromodulation
#acute-brain-injury
#electrophysiology
|
|
14
|
|
Global change reshapes marine microbial communities, functions and One Health outcomes.
(nature.com)
|
Peixoto RS
…
Garcia FC
Nature Reviews Microbiology
2026-11-04
|
#microbiome
#marine
#climate
#biogeochemical
#amr
|
|
14
|
|
Efficient and accurate mixed model association tool for single-cell eQTL analysis.
(nature.com)
|
Zhou W
…
Neale BM
Nature Genetics
2026-11-06
|
#transcriptomics
#eqtl
#single-cell
#genetics
#immunity
|
|
14
|
|
Robust fine-mapping in the presence of linkage disequilibrium mismatch.
(nature.com)
|
Zhang W
…
Lettre G
Nature Genetics
2026-11-06
|
#fine mapping
#genome-wide association
#linkage disequilibrium
#qtl
#causal inference
|