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44
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Reconstructing developmental and disease progression with sample-level embeddings.
(linkinghub.elsevier.com)
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Jiang L
…
Satija R
Cell
2026-11-09
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#single-cell
#transcriptomics
#disease-progression
#heterogeneity
#embedding
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36
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A stroma-sensing TGF-beta blockade reprograms CAF-myeloid niches to induce durable tumor immunity.
(linkinghub.elsevier.com)
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Kang DW
…
Kim SJ
Cancer Cell
2026-11-09
|
#immunotherapy
#cancer
#microenvironment
#fibrosis
#immunity
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36
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Neutrophils are known by their neighbors in breast cancer.
(linkinghub.elsevier.com)
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Pei S
…
Ng LG
Cancer Cell
2026-11-09
|
#immunology
#cancer
#spatial omics
#microenvironment
#immunotherapy
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36
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Decoding neutrophil spatial heterogeneity and clinical implications in breast cancer.
(linkinghub.elsevier.com)
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Xu YZ
…
Shao ZM
Cancer Cell
2026-11-09
|
#spatial omics
#immunotherapy
#breast cancer
#neutrophil
#tumor microenvironment
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33
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ANGPTL4 Inhibition in Adults with Elevated Triglyceride Levels.
(nejm.org)
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O'Donoghue ML
…
Sabatine MS
New England Journal of Medicine
2026-11-09
|
#triglycerides
#monoclonal-antibody
#lipid metabolism
#clinical trial
#dyslipidemia
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25
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Hemodynamic effects of semaglutide in individuals with heart failure with preserved ejection fraction and obesity: a placebo-controlled randomized clinical trial.
(nature.com)
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Borlaug BA
…
Carter RE
Nature Medicine
2026-11-08
|
#heart failure
#hemodynamics
#obesity
#randomized-trial
#glp-1
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25
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Effects of semaglutide on cardiac structure and function in heart failure with preserved ejection fraction and obesity: a pre-specified cardiac magnetic resonance substudy of the CAMEO-SEMA trial.
(nature.com)
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Ghanbari F
…
Borlaug BA
Nature Medicine
2026-11-08
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#heart failure
#obesity
#cardiac-imaging
#glp1-agonists
#hemodynamics
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25
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Retatrutide Once Weekly in Adults with Knee Osteoarthritis Pain and Obesity.
(nejm.org)
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Schnitzer TJ
…
Forrester T
New England Journal of Medicine
2026-11-08
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#osteoarthritis
#obesity
#pharmacotherapy
#clinical trial
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25
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|
Community and EMS Interventions to Improve Survival in Cardiac Arrest.
(nejm.org)
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Malta Hansen C
…
Granger CB
New England Journal of Medicine
2026-11-08
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#cardiac arrest
#resuscitation
#emergency-medicine
#intervention
#outcomes
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25
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|
Left Bundle-Branch Pacing versus Right Ventricular Pacing for Atrioventricular Block.
(nejm.org)
|
Qian Z
…
Zou J
New England Journal of Medicine
2026-11-08
|
#pacing
#arrhythmia
#cardiology
#heart failure
#randomized-trial
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22
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|
Efficacy and safety of efinopegdutide in adults with metabolic dysfunction-associated steatohepatitis and stage 2-3 fibrosis: a phase 2b, randomised, placebo-controlled study.
(linkinghub.elsevier.com)
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Lawitz E
…
Schattenberg JM
The Lancet
2026-11-09
|
#steatohepatitis
#fibrosis
#pharmacotherapy
#clinical trial
#liver
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22
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|
Cardiovascular outcomes with survodutide in adults with obesity at increased cardiovascular risk (SYNCHRONIZE-CVOT): a double-blind, randomised, placebo-controlled, phase 3 trial.
(linkinghub.elsevier.com)
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Bozkurt B
…
Kaplan LM
The Lancet
2026-11-09
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#obesity
#cardiovascular
#clinical trial
#glp-1
#pharmacotherapy
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18
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Intensive Blood-Pressure Control in Patients with Previous Ischemic Stroke.
(nejm.org)
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Sampaio Silva G
…
Berwanger O
New England Journal of Medicine
2026-11-07
|
#hypertension
#stroke
#cardiovascular
#clinical trial
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18
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|
Interleukin-6 Inhibition with Ziltivekimab for Atherosclerotic Disease.
(nejm.org)
|
Ridker PM
…
Perkovic V
New England Journal of Medicine
2026-11-07
|
#atherosclerosis
#inflammation
#cardiovascular
#immunotherapy
#cytokine
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18
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Discontinuing Statins in Older Adults without Cardiovascular Disease.
(nejm.org)
|
Rodondi N
…
Trelle S
New England Journal of Medicine
2026-11-07
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#cardiovascular
#statins
#prevention
#clinical trial
#aging
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18
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|
Pelacarsen and Cardiovascular Outcomes in Patients with High Lipoprotein(a).
(nejm.org)
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Cho L
…
Nissen SE
New England Journal of Medicine
2026-11-07
|
#cardiovascular
#lipoprotein
#antisense
#therapeutics
|
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18
|
|
Intensive Blood-Pressure Lowering in Patients with Type 2 Diabetes.
(nejm.org)
|
Santo K
…
Berwanger O
New England Journal of Medicine
2026-11-07
|
#hypertension
#diabetes
#randomized-trial
#cardiovascular
#adverse outcomes
|
|
18
|
|
Prehospital Extracorporeal Life Support in Refractory Out-of-Hospital Cardiac Arrest.
(nejm.org)
|
Reis Miranda D
…
Gommers D
New England Journal of Medicine
2026-11-07
|
#resuscitation
#cardiac arrest
#ecmo
#prehospital
|
|
17
|
|
Melting and resistivity of iron at Earth core conditions using pulsed Joule heating.
(science.org)
|
Geballe ZM
…
Walter MJ
Science
2026-11-08
|
#metallurgy
#geophysics
#high-pressure
#thermodynamics
|
|
15
|
|
Promoter-proximal pausing enables transcriptional buffering of RNA polymerase II availability.
(linkinghub.elsevier.com)
|
Olthof AM
…
Svejstrup JQ
Molecular Cell
2026-11-09
|
#transcriptomics
#pausing
#elongation
#splicing
|