|
22
|
|
RNAactDrug 2.0: an updated resource for systematically exploring molecular features associated with drug sensitivity across multi-omics datasets.
(academic.oup.com)
|
Li F
…
Xu Y
Nucleic Acids Research
2026-11-02
|
#pharmacogenomics
#transcriptomics
#cancer
#single-cell
#epigenetics
|
|
14
|
|
Targeting N-acetyltransferase 10 reprograms Treg function to enhance anti-PD-1 immunotherapy sensitivity in murine lung tumors.
(jci.org)
|
Qi X
…
Li F
Journal of Clinical Investigation
2026-11-02
|
#immunosuppression
#cancer
#immunotherapy
#checkpoint_inhibition
#epigenetics
|
|
14
|
|
Nuclear cGAS governs transcription to control lipid metabolism, tumor growth, and therapy response.
(jci.org)
|
Deng Y
…
Liu P
Journal of Clinical Investigation
2026-11-02
|
#metabolism
#transcriptomics
#immunity
#chromatin
#cancer
|
|
14
|
|
Neoadjuvant PD-L1/TGF-beta blockade can rapidly disrupt the tumor stroma in head and neck cancer patients.
(jci.org)
|
Hoffmann C
…
Salmon H
Journal of Clinical Investigation
2026-11-02
|
#cancer
#immunotherapy
#stroma
#transcriptomics
#fibroblast
|
|
14
|
|
Multi-omics survival prediction under modality incompleteness via dynamic modality graphs and product-of-experts fusion.
(academic.oup.com)
|
Xie W
…
Li W
Briefings in Bioinformatics
2026-11-02
|
#cancer
#multi-omics
#survival
#prediction
#integration
|
|
13
|
|
Mitochondrial DNA abundance is a determinant of immunogenic cell death in cancer.
(linkinghub.elsevier.com)
|
Tanaka K
…
Nishikawa H
Immunity
2026-10-30
|
#cancer
#immunotherapy
#mitochondrial
#immunity
#apoptosis
|
|
12
|
|
Intratumoral cDC1-T cell clusters serve as sites of local costimulation to enhance CTL-mediated tumor rejection.
(pnas.org)
|
Carbone CB
…
Moussion C
PNAS
2026-11-02
|
#immunotherapy
#t cell
#tumor immunity
#dendritic cell
#cancer
|
|
10
|
|
Surveillance Mammography and Second Primary Breast Cancer Diagnosis Among Older Women With a History of Breast Cancer.
(jamanetwork.com)
|
Richman IB
…
Berger ER
JAMA Internal Medicine
2026-11-02
|
#cancer
#mammography
#screening
#surveillance
#prognosis
|
|
10
|
|
GALE is a tumor-intrinsic checkpoint of Vgamma9Vdelta2 T cell-mediated killing.
(nature.com)
|
Shan Z
…
Wang P
Nature Cancer
2026-10-30
|
#cancer
#immunotherapy
#immunity
#glycosylation
#metabolism
|
|
9
|
|
Phase separation of SMARCAL1 orchestrates epigenetic reprogramming and methionine metabolism to foster radioresistance and immunosuppression.
(nature.com)
|
Zheng CC
…
Li B
Nature Cell Biology
2026-10-30
|
#epigenetics
#radioresistance
#cancer
#immunotherapy
#phase separation
|
|
9
|
|
Enhanced cfDNA methylation profiling by detection and correction of jagged ends.
(nature.com)
|
Wang R
…
Alizadeh AA
Nature Methods
2026-10-29
|
#methylation
#epigenetics
#cfdna
#cancer
#sequencing
|
|
9
|
|
XYcellAtlas: a cell-type- and spatial-resolved pan-cancer atlas of sex-biased and Y chromosome loss-associated molecular signatures.
(academic.oup.com)
|
Fan T
…
Sun Z
Nucleic Acids Research
2026-10-30
|
#transcriptomics
#cancer
#single-cell
#epigenomics
#sex-differences
|
|
7
|
|
T cell cross-priming by PD-L1(+) type 1 conventional dendritic cells mediates the antitumor efficacy of a PD-L1x4-1BB bispecific antibody.
(linkinghub.elsevier.com)
|
Luri-Rey C
…
Melero I
Immunity
2026-10-28
|
#immunotherapy
#dendritic cell
#cancer
#antigen-presentation
#activation
|
|
7
|
|
Integrative discovery and functional dependency mapping uncover essential chimeric RNAs in the active transcriptome.
(science.org)
|
Lalani S
…
Li H
Science Advances
2026-10-30
|
#transcriptomics
#cancer
#fusion
|
|
7
|
|
Oxygen-dependent constraint of glycolysis through the mitochondrial electron transport chain.
(science.org)
|
Guajardo-Grence A
…
Aragones J
Science Advances
2026-10-30
|
#mitochondria
#hypoxia
#glycolysis
#metabolism
#cancer
|
|
7
|
|
Evidence of active whole-genome doubling (WGD) subclones in non-WGD tumors.
(science.org)
|
He F
…
Zheng S
Science Advances
2026-10-30
|
#cancer
#clonal
#genomics
#evolution
#transcriptomics
|
|
7
|
|
A genome‑wide screen in E. coli reveals metabolic adaptations that enhance intratumoral fitness and bacterial cancer therapy efficacy.
(nature.com)
|
Chen N
…
Arpaia N
Nature Cancer
2026-10-29
|
#metabolism
#cancer
#screening
#immunotherapy
#microbiome
|
|
7
|
|
Methylated eEF1A selectively decodes mRNA to shape cancer proteomes.
(nature.com)
|
Liu S
…
Mazur PK
Nature Cell Biology
2026-10-29
|
#proteomics
#cancer
#methylation
#translation
#amr
|
|
6
|
|
SpatioCAD: Context-aware graph diffusion model for pinpointing spatially variable genes in heterogeneous tissues.
(journals.plos.org)
|
Wen H
…
Zhang S
PLOS Computational Biology
2026-11-02
|
#transcriptomics
#cancer
#tissue
#computational
|
|
6
|
|
SWI/SNF complexes shape 3D chromatin architecture through CTCF and cohesin.
(nature.com)
|
Debek S
…
Barisic D
Nature
2026-10-28
|
#chromatin
#cancer
#remodeling
#transcriptomics
|