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22
|
|
PASTA: versatile tyramide-oligonucleotide amplification for multimodal spatial biology.
(nature.com)
|
Michel HA
…
Jiang S
Nature Methods
2026-08-17
|
#proteomics
#imaging
#multiplexing
#amplification
#transcriptomics
|
|
18
|
|
Identifying phenotype-genotype-function coupling in 3D organoid imaging using Shape, Appearance and Motion Phenotype Observation Tool (SPOT).
(nature.com)
|
Zhou FY
…
Lu X
Nature Communications
2026-08-17
|
#phenotyping
#organoid
#imaging
#morphogenesis
#transcriptomics
|
|
17
|
|
Brain perivascular macrophages regulate endothelial cell function via a cMAF-dependent transcriptional program in mouse and human.
(linkinghub.elsevier.com)
|
Brioschi S
…
Colonna M
Cell
2026-08-14
|
#transcriptomics
#macrophage
#neuroinflammation
#neurodegeneration
#endothelial
|
|
14
|
|
Pervasive noise in human pre-mRNA splice site selection.
(linkinghub.elsevier.com)
|
Khokhar ES
…
Pai AA
Molecular Cell
2026-08-17
|
#splicing
#transcriptomics
#rna
#sequencing
#noise
|
|
14
|
|
CD73 inhibition overcomes adaptive immune resistance to PARP inhibiton in models of prostate cancer.
(jci.org)
|
Xie P
…
Zhang B
Journal of Clinical Investigation
2026-08-18
|
#immunotherapy
#prostate cancer
#transcriptomics
#checkpoint_inhibition
#dna repair
|
|
14
|
|
Convection-enhanced delivery of dexamethasone in glioma models suppresses myeloid inflammation while avoiding systemic toxicities.
(jci.org)
|
Rolfe NW
…
Bruce JN
Journal of Clinical Investigation
2026-08-18
|
#glioma
#inflammation
#immunotherapy
#microglia
#transcriptomics
|
|
14
|
|
From environmental signals to adaptive phenotypes: signal-responsive regulation and network logic of bacterial small RNAs.
(academic.oup.com)
|
Yi Z
…
Wang W
FEMS Microbiology Reviews
2026-08-17
|
#transcriptomics
#regulation
#virulence
|
|
13
|
|
Histological aging signatures for monitoring tissue-specific aging and disease.
(nature.com)
|
Abila E
…
Rendeiro AF
Nature Medicine
2026-08-14
|
#aging
#histopathology
#deeplearning
#biomarker
#transcriptomics
|
|
10
|
|
Emerging roles of ATR beyond DNA damage repair: orchestrating transcriptional reprogramming during epithelial-to-mesenchymal transition.
(jci.org)
|
Mestre-Farrera A
…
Yang J
Journal of Clinical Investigation
2026-08-17
|
#emt
#metastasis
#cancer
#kinase
#transcriptomics
|
|
9
|
|
Single-cell 3D genome imaging shows super-enhancer hubs are rare, nonspecific, and neither necessary nor sufficient for transcriptional bursting.
(linkinghub.elsevier.com)
|
Le DJ
…
Boettiger AN
Cell Genomics
2026-08-17
|
#transcriptomics
#enhancer
#imaging
#chromatin
#transcription
|
|
9
|
|
Selective saccular plasticity under microgravity links peripheral transcriptomic remodeling to postflight vestibular dysfunction.
(pnas.org)
|
Abe C
…
Morita H
PNAS
2026-08-17
|
#vestibular
#transcriptomics
#microgravity
#plasticity
#adaptation
|
|
9
|
|
The role of small Heat Shock Proteins in Trypanosoma cruzi infection and intestinal homeostasis in a Chagas disease vector.
(pnas.org)
|
Guedes-Silva TC
…
Oliveira PL
PNAS
2026-08-17
|
#chagas
#transcriptomics
#homeostasis
#parasitism
#stress response
|
|
8
|
|
Circadian rhythms in microglia mediate early life synaptic development in a sex-specific manner.
(linkinghub.elsevier.com)
|
Routh BN
…
Fonken LK
Cell Reports
2026-08-17
|
#circadian
#microglia
#synaptogenesis
#neurodevelopment
#transcriptomics
|
|
8
|
|
Caloric restriction suppresses colorectal tumors and melanoma through CD8 T cells in aged mice.
(linkinghub.elsevier.com)
|
Horino T
…
Oike Y
Cell Reports
2026-08-17
|
#immunotherapy
#cancer
#immunity
#aging
#transcriptomics
|
|
8
|
|
Canonical and non-canonical miRNA degradation shapes state transitions and stemness in breast cancer.
(link.springer.com)
|
Rubolino C
…
Nicassio F
The EMBO Journal
2026-08-17
|
#microrna
#breast cancer
#transcriptomics
#stemness
#drug resistance
|
|
8
|
|
Transcriptional regulation drives heteroresistance in Pseudomonas aeruginosa: evidence from genomic and targeted gene expression analysis.
(journals.asm.org)
|
Feng W
…
Zhao Z
mSystems
2026-08-18
|
#amr
#transcriptomics
#pseudomonas
#sequencing
|
|
8
|
|
The bacterial pH gradient contributes to persistence in Mycobacterium tuberculosis.
(journals.asm.org)
|
Eldesouky HE
…
Sherman DR
mBio
2026-08-18
|
#tb
#persistence
#antibiotic tolerance
#transcriptomics
#amr
|
|
8
|
|
PLCG2 downregulation impairs synaptic function and increases Alzheimer's disease hallmarks in neuronal cultures.
(nature.com)
|
Coulon A
…
Lambert JC
Nature Genetics
2026-08-14
|
#neurodegeneration
#synaptic
#transcriptomics
#genetics
|
|
8
|
|
Spatial analysis of head and neck cancer identifies two ecosystems with distinct modes of epithelial-to-mesenchymal transition.
(nature.com)
|
Simkin D
…
Tirosh I
Nature Genetics
2026-08-14
|
#transcriptomics
#cancer
#epithelial-mesenchymal transition
#microenvironment
|
|
7
|
|
Characterizing intra- and intertumor heterogeneity in ovarian high-grade serous carcinoma subtypes using single-cell and spatial transcriptomics.
(genome.cshlp.org)
|
Li W
…
Hicks SC
Genome Research
2026-08-17
|
#transcriptomics
#cancer
#heterogeneity
#immunity
|