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#autoimmunity
— top 20, last 7d
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Depletion of extracellular asparagine impairs self-reactive T cells and ameliorates autoimmunity in a murine model of multiple sclerosis.
(elifesciences.org)
Georgiev P
…
Sharpe AH
eLife
2026-07-08
#autoimmunity
#metabolism
#t cell
#encephalomyelitis
#immunometabolism
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Circulating PEG-indoleamine 2,3-dioxygenase ameliorates diverse inflammatory diseases without toxicity or compromising immunocompetence.
(pnas.org)
Simonovich JA
…
Keselowsky BG
PNAS
2026-07-08
#immunomodulation
#inflammation
#autoimmunity
#protein-therapy
#tryptophan-metabolism
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Circadian screening of neutrophils identifies therapeutic targets in multiple sclerosis.
(pnas.org)
De Virgiliis F
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Scheiermann C
PNAS
2026-07-08
#circadian
#autoimmunity
#neutrophil
#transcriptomics
#neuroinflammation
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Gut metaproteomics reveals activated arginine catabolism and impaired arginine biosynthesis in systemic lupus erythematosus.
(journals.asm.org)
Xiong W
…
Wang Q
mSystems
2026-07-10
#metaproteomics
#microbiome
#autoimmunity
#metabolism
#dysbiosis
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Systemic lupus erythematosus: Phase 2 trials to watch in 2026.
(linkinghub.elsevier.com)
Morand EF
…
Jones SA
Cell Med
2026-07-10
#lupus
#autoimmunity
#clinical-trials
#immunology
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Engineering trispecific IL-2 receptor agonistic antibodies through geometry optimization for enhanced Treg targeting.
(nature.com)
Lykhopiy V
…
Schlenner SM
Nature Communications
2026-07-10
#immunotherapy
#antibody
#autoimmunity
#immunoengineering
#tolerance