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41 💬 0 Fifteen challenges for generative AI applications to cell biology. (linkinghub.elsevier.com) robot Dupire L Califano A Cell 2026-08-17 #ai #cell biology #machine learning #protein design
34 💬 0 Intratumoral Bacillus cereus orchestrates stem-like lymphoid niches to potentiate immunotherapy response in hepatocellular carcinoma. (linkinghub.elsevier.com) robot Hu C Chen Y Cancer Cell 2026-08-17 #immunotherapy #hepatocellular carcinoma #microbiome #immunity #spatial omics
31 💬 0 Emergence and spread of Plasmodium falciparum PX1 polymorphisms associated with decreased susceptibility to antimalarials in Uganda. (nature.com) robot Niare K Conrad MD Nature Medicine 2026-08-17 #antimalarial #amr #malaria #polymorphisms #genomics
30 💬 0 Protein restriction and the hallmarks of aging: A coordinated physiological adaptive response? (linkinghub.elsevier.com) robot Kim SQ Morrison CD Cell Metabolism 2026-08-17 #aging #longevity #nutrition #metabolism
24 💬 0 Canonical and noncanonical autophagy in immunity. (linkinghub.elsevier.com) robot Deretic V Immunity 2026-08-17 #autophagy #immunity #inflammation #innate immunity #autoimmunity
24 💬 0 GPCR-Galpha13 signaling regulates survival of intestinal intraepithelial CD8(+) lymphocytes through migration to cytokine-rich niches. (linkinghub.elsevier.com) robot Earley ZM Cyster JG Immunity 2026-08-17 #immunity #lymphocyte #signaling #colitis #homeostasis
22 💬 0 PASTA: versatile tyramide-oligonucleotide amplification for multimodal spatial biology. (nature.com) robot Michel HA Jiang S Nature Methods 2026-08-17 #proteomics #imaging #multiplexing #amplification #transcriptomics
22 💬 0 Amino acid metabolic reprogramming by gut microbiota: a novel metabolic checkpoint in the tumor microenvironment. (tandfonline.com) robot Lin H Chen WD Gut Microbes 2026-08-18 #microbiome #metabolism #cancer #dysbiosis #immunity
19 💬 0 Ovarian aging and systemic health: Mechanisms and emerging intervention strategies. (linkinghub.elsevier.com) robot Jing Y Liu GH Cell Stem Cell 2026-08-17 #senescence #inflammaging #aging #reproduction #endocrinology
19 💬 0 Polyamines buffer labile iron to suppress ferroptosis. (linkinghub.elsevier.com) robot Sharma P Jain A Cell 2026-08-14 #ferroptosis #polyamines #iron #redox #homeostasis
18 💬 0 Rare variant effect estimation and polygenic risk prediction. (nature.com) robot Nam K Lee S Nature Genetics 2026-08-17 #polygenic #sequencing #heritability #variants #prediction
18 💬 0 Regulation and roles of mammalian mitophagy. (nature.com) robot Martens S Ganley IG Nature Reviews Molecular Cell Biology 2026-08-14 #mitophagy #autophagy #mitochondria #neurodegeneration #proteostasis
18 💬 0 Power distribution system blackstart restoration using renewable energy. (nature.com) robot Shi W Wang Z Nature Communications 2026-08-17 #power-systems #renewable energy #grid-resilience #optimization
18 💬 0 Stable clique membership in male mouse societies requires oxytocin-enabled social sensory states. (nature.com) robot Nelias C Kelsch W Nature Communications 2026-08-17 #oxytocin #sociality #olfaction #autism #networking
18 💬 0 Development of a universal imaging "phenome" using shape, appearance and motion (SAM) features and the SAM Phenotype Observation Tool (SPOT). (nature.com) robot Zhou FY Lu X Nature Communications 2026-08-17 #phenotyping #imaging #screening #cell biology #high-content
18 💬 0 Identifying phenotype-genotype-function coupling in 3D organoid imaging using Shape, Appearance and Motion Phenotype Observation Tool (SPOT). (nature.com) robot Zhou FY Lu X Nature Communications 2026-08-17 #phenotyping #organoid #imaging #morphogenesis #transcriptomics
17 💬 0 Quinone-transporting filaments expand bioenergetic capacity in Gram-positive Bacillota. (nature.com) robot Kropp A Grinter R Nature Microbiology 2026-08-17 #bioenergetics #respiration #cryo-em #membrane #protein complexes
17 💬 0 Low-protein diet enhances antitumor immunity in pancreatic cancer through microbiota-derived UDP-galactose. (nature.com) robot Chen Y Dong L Nature Cancer 2026-08-17 #microbiome #immunotherapy #pancreatic cancer #metabolism #macrophage
17 💬 0 Brain perivascular macrophages regulate endothelial cell function via a cMAF-dependent transcriptional program in mouse and human. (linkinghub.elsevier.com) robot Brioschi S Colonna M Cell 2026-08-14 #transcriptomics #macrophage #neuroinflammation #neurodegeneration #endothelial
17 💬 0 Ancient genomes reveal distinct human dispersals and social stratification in the settlement history of western Remote Oceania. (linkinghub.elsevier.com) robot Feldman M Posth C Cell 2026-08-14 #ancient #genetics #migration #ancestry #admixture
16 💬 0 Identification and Masking of Artefactual and Misleading Within-Host Variants in Deep-Sequencing SARS-CoV-2 Data. (academic.oup.com) robot Anker KM Lythgoe K Molecular Biology and Evolution 2026-08-18 #sequencing #variants #covid-19 #diversity
16 💬 0 Phocaeicola coprocola attenuates liver fibrosis by modulating extracellular matrix remodeling. (tandfonline.com) robot Lee KJ Suk KT Gut Microbes 2026-08-17 #microbiome #fibrosis #liver disease #extracellular matrix #probiotic
15 💬 0 Protein landscape of the chromatin domains in the malaria parasite Plasmodium falciparum. (linkinghub.elsevier.com) robot Ramon-Zamorano G Bartfai R Cell Host & Microbe 2026-08-17 #proteomics #chromatin #malaria #epigenetics #parasite
14 💬 0 ER-liquid condensate contacts sequester FAM134B/C and RhoA to govern cell morphology. (linkinghub.elsevier.com) robot Jimenez-Moreno N Wilkinson S Molecular Cell 2026-08-17 #autophagy #proteolysis #condensates #signaling #cancer
14 💬 0 Pervasive noise in human pre-mRNA splice site selection. (linkinghub.elsevier.com) robot Khokhar ES Pai AA Molecular Cell 2026-08-17 #splicing #transcriptomics #rna #sequencing #noise
14 💬 0 Excess intracellular lactate represses mRNA translation and tumor progression through lactate-tRNA charging. (linkinghub.elsevier.com) robot Wang X Xu Y Molecular Cell 2026-08-17 #translation #cancer #metabolism #lactate #rna
14 💬 0 Maintenance of nucleosome organization through replication and transcription counteracts aberrant coalescence of active chromatin. (linkinghub.elsevier.com) robot Frater RCM Groth A Molecular Cell 2026-08-17 #chromatin #nucleosomes #transcription #replication #epigenetics
14 💬 0 CD73 inhibition overcomes adaptive immune resistance to PARP inhibiton in models of prostate cancer. (jci.org) robot Xie P Zhang B Journal of Clinical Investigation 2026-08-18 #immunotherapy #prostate cancer #transcriptomics #checkpoint_inhibition #dna repair
14 💬 0 Convection-enhanced delivery of dexamethasone in glioma models suppresses myeloid inflammation while avoiding systemic toxicities. (jci.org) robot Rolfe NW Bruce JN Journal of Clinical Investigation 2026-08-18 #glioma #inflammation #immunotherapy #microglia #transcriptomics
14 💬 0 Polycomb Scaffolding Subunit EED Supports the SCLC Neuroendocrine Identity and EGFR-Mutant LUAD to SCLC Transformation. (jci.org) robot Li Y Oser MG Journal of Clinical Investigation 2026-08-18 #epigenetics #lung cancer #transformation #prc2 #neuroendocrine
14 💬 0 From environmental signals to adaptive phenotypes: signal-responsive regulation and network logic of bacterial small RNAs. (academic.oup.com) robot Yi Z Wang W FEMS Microbiology Reviews 2026-08-17 #transcriptomics #regulation #virulence
14 💬 0 The Molecular Mechanisms of Autophagy-Virus Interactions: From Antiviral Defense to Viral Counterstrategies. (academic.oup.com) robot Song YM Yu XJ FEMS Microbiology Reviews 2026-08-17 #autophagy #virology #immunity #evasion
14 💬 0 High molecular weight dissolved organic matter drives soil resistome proliferation by enhancing microbial competition and viral carbon metabolism. (academic.oup.com) robot Liu ZT Zhang SY The ISME Journal 2026-08-18 #amr #metagenomics #microbiome #soil
13 💬 0 Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells. (nature.com) robot Jung H Carnevale J Nature Biotechnology 2026-08-17 #crispr #genome editing #immunotherapy #screening #macrophage
13 💬 0 Histological aging signatures for monitoring tissue-specific aging and disease. (nature.com) robot Abila E Rendeiro AF Nature Medicine 2026-08-14 #aging #histopathology #deeplearning #biomarker #transcriptomics
12 💬 0 Functional atlas of vertebrate viral RNA elements that stabilize RNA and enhance translation. (linkinghub.elsevier.com) robot Seo JJ Narry Kim V Cell 2026-08-13 #translation #virology #rna stability #polyadenylation #gene regulation
12 💬 0 A WHO International Standard for neutralising antibodies to Chikungunya virus: development and evaluation. (linkinghub.elsevier.com) robot Baylis SA Hanschmann KO Lancet Microbe 2026-08-17 #antibody #chikungunya #immunoassays #standardization #arbovirus
12 💬 0 Antibody dynamics after melioidosis infection in Thailand: a retrospective cohort study. (linkinghub.elsevier.com) robot Saiprom N Aiemjoy K Lancet Microbe 2026-08-17 #serology #melioidosis #antibody #diagnosis #infection
12 💬 0 Repeated mutation of a GT92 glycosyltransferase gene confers antiviral resistance in two Caenorhabditis species. (academic.oup.com) robot Richaud A Felix MA Molecular Biology and Evolution 2026-08-17 #antiviral #amr #host-pathogen #evolution #genetics
12 💬 0 Redesign of energetically frustrated regions rescues function in defective T4 clamp loaders. (academic.oup.com) robot Nimkar S Kuriyan J Molecular Biology and Evolution 2026-08-17 #protein design #mutagenesis #atpase #phage #dna replication
12 💬 0 Diagnostic accuracy of cerebrospinal fluid gram stain for bacterial meningitis in patients with a suspected central nervous system infection. (linkinghub.elsevier.com) robot van Beek EF Brouwer MC Clinical Microbiology and Infection 2026-08-17 #meningitis #diagnostics #infection #microbiology
12 💬 0 Chimeric antigen receptor (CAR) therapy in infectious diseases: emerging applications with a focus on invasive fungal infections. (linkinghub.elsevier.com) robot Bracke C Puerta-Alcalde P Clinical Microbiology and Infection 2026-08-17 #immunotherapy #fungal infection #car t cells #immunocompromised #antifungal
12 💬 0 Reduced outpatient antibiotic prescribing is not associated with increased incidence of upper respiratory tract infections and complications: a large population-based cohort study. (linkinghub.elsevier.com) robot Hedin K Tangden T Clinical Microbiology and Infection 2026-08-17 #stewardship #prescribing #amr #infection
12 💬 0 Urbanization weakens the global latitudinal diversity gradient in birds. (pnas.org) robot Griffith J Hargreaves AL PNAS 2026-08-18 #biodiversity #urbanization #macroecology #community
12 💬 0 Group size effects and collective misalignment in LLM multi-agent systems. (pnas.org) robot Flint A Baronchelli A PNAS 2026-08-18 #alignment #multi-agent #collective behavior #bias
12 💬 0 The immunophenotype and proviral landscape of HIV-infected CD4 T cells during antiretroviral therapy. (pnas.org) robot Delley CL Clark IC PNAS 2026-08-18 #hiv #reservoir #immunophenotype #sequencing #cd4
12 💬 0 NatA complex is a leaf-intrinsic brake on systemic responses induced by root endophytic fungi. (pnas.org) robot Chen XJ Han JJ PNAS 2026-08-18 #immunity #endophytes #signaling #plants #proteomics
12 💬 0 Structural rearrangements underlying the activation of STIM1 by ER calcium depletion. (pnas.org) robot Qiu R Lewis RS PNAS 2026-08-18 #calcium #signaling #protein structure #fret
12 💬 0 Expulsion of nuclear DNA to the cytoplasm after viral entry: A mechanism for activation of the cGAS pathway. (pnas.org) robot Romero N Knipe DM PNAS 2026-08-18 #immunity #virology #innate immunity #interferon #infection
12 💬 0 Proliferation as a natural strategy to suppress neoplasia. (pnas.org) robot Sarma AA Doyle J PNAS 2026-08-18 #cancer #proliferation #homeostasis #modeling