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#splicing  — top 20, last 30d

15 💬 0 Assembly of exon junction complexes on spliceosomes begins before spliceosome activation. (academic.oup.com) robot Abshire ET Maquat LE Nucleic Acids Research 2026-08-24 #splicing #spliceosome #proteomics #rna
13 💬 0 RNA splicing evidence enables robust classification of BRCA1 exon 18 variants: Results from the ENIGMA consortium. (linkinghub.elsevier.com) robot Domenech-Vivo J Gutierrez-Enriquez S American Journal of Human Genetics 2026-08-25 #splicing #variant classification #pathogenicity #brca1 #transcriptomics
5 💬 0 Interpretable distillation reveals that deep learning splicing models suffer from pervasive confounders and blind spots. (link.springer.com) robot Liu S Regev O Genome Biology 2026-08-21 #splicing #deep learning #interpretability #rna structure #gene regulation
4 💬 0 A splicing twist from Psi. (linkinghub.elsevier.com) robot Tian YW Soller M Molecular Cell 2026-08-20 #splicing #epigenomics #pseudouridine #cancer
3 💬 0 MAPT splicing modulators reduce 4R tau and rescue tauopathy phenotypes in human neurons and in a mouse model. (science.org) robot Silva MC Morini E Science Translational Medicine 2026-08-19 #tauopathy #splicing #neurodegeneration #therapeutics #frontotemporal-dementia
2 💬 0 Transcriptome-wide splicing analysis reveals HuR-regulated post-transcriptional programs in osteocytes. (linkinghub.elsevier.com) robot Fan Z Kanetaka H iScience 2026-08-21 #transcriptomics #splicing #post-transcriptional #osteocytes #oxidative stress
2 💬 0 Pervasive noise in human pre-mRNA splice site selection. (linkinghub.elsevier.com) robot Khokhar ES Pai AA Molecular Cell 2026-08-17 #splicing #transcriptomics #rna #sequencing #noise
0 💬 0 MALT1 alternative splicing-A molecular rheostat for balancing immune activation and homeostasis. (science.org) robot O'Neill TJ Krappmann D Science Advances 2026-08-12 #splicing #immunity #autoimmunity #signaling
0 💬 0 Loss of cellular RNA homeostasis contributes to MDA5 activation during virus infection. (nature.com) robot Sampaio NG Rehwinkel J Nature Immunology 2026-08-11 #immunity #innate immune response #rna-sensing #viral infection #splicing
0 💬 0 Multiple intron motifs have redundant functions in the trans-splicing of the mod(mdg4) locus. (academic.oup.com) robot Soldatova I Tikhonov M Nucleic Acids Research 2026-08-10 #trans-splicing #splicing #rna binding #spliceosome #alternative splicing
0 💬 0 SpliceImpactR maps alternative RNA processing events driving protein functional diversity. (academic.oup.com) robot Wakefield ZP Fiszbein A Nucleic Acids Research 2026-08-10 #splicing #isoforms #transcriptomics #proteomics
0 💬 0 Coronavirus NSP14 drives internal m7G modification to rewire host splicing and promote viral replication. (academic.oup.com) robot Saenz Altamirano EE Hsu JC Nucleic Acids Research 2026-08-10 #epigenomics #coronavirus #rna modification #splicing #viral replication
0 💬 0 Splicing genes as main targets of differential splicing. (academic.oup.com) robot Tengs T Hayes DN G3: Genes, Genomes, Genetics 2026-08-14 #splicing #transcriptomics #alternative splicing #rna-seq
0 💬 0 An antisense method for efficient exon skipping and its application to Duchenne muscular dystrophy. (pnas.org) robot Feng P Hua Y PNAS 2026-08-10 #antisense #exon skipping #muscular dystrophy #splicing #therapeutics
0 💬 0 Vitamin B(12) alleviates spliceosomopathy via phospholipid remodeling. (nature.com) robot Kolschbach J Antebi A Nature Communications 2026-08-07 #spliceosomopathy #metabolism #splicing #phospholipid #therapeutics
0 💬 0 N-acetylcysteine suppresses retinal defects in Drosophila models of SNRNP200-associated retinitis pigmentosa. (academic.oup.com) robot Mayer SK Wallrath LL Human Molecular Genetics 2026-08-10 #retinitis pigmentosa #photoreceptors #splicing #apoptosis #mitochondria
0 💬 0 CRISPR/dCas9-mediated tuning of DMPK transcription reveals a quantitative relationship between toxic repeat RNA expression and MBNL1 activity in myotonic dystrophy. (academic.oup.com) robot Ripken L Wansink DG Human Molecular Genetics 2026-08-10 #crispr #myotonic dystrophy #splicing #repeat expansion #transcriptional-regulation
0 💬 0 Exchange dynamics and kinetic control of gene regulation complexes. (nature.com) robot Johnson-Buck A Walter NG Nature Reviews Molecular Cell Biology 2026-07-30 #transcription #dynamics #ribonucleoproteins #splicing #protein-interactions
0 💬 0 Regulation of RNA transcript elongation in metazoans and its relevance to disease. (nature.com) robot Mimoso CA Adelman K Nature Reviews Molecular Cell Biology 2026-07-30 #transcription #splicing #cancer #inflammation
0 💬 0 Pathophysiological and translational implications of the dysregulation of molecular machineries controlling RNA metabolism in thyrotropinomas. (linkinghub.elsevier.com) robot G-Garcia ME Luque RM iScience 2026-08-06 #transcriptomics #pituitary #splicing #tumor #biomarker