|
0
|
|
High-throughput screening identifies a critical role of the SPOP-PABPC1 axis in lung adenocarcinoma progression.
(pnas.org)
|
Zhang J
…
Gong L
PNAS
2026-06-16
|
#ubiquitination
#cancer
#proteomics
#transcriptomics
#proliferation
|
|
0
|
|
The molecular basis for nuclear pore destruction by a proximity-inducing molecular glue.
(linkinghub.elsevier.com)
|
Hinshaw SM
…
Corsello SM
Cell Chemical Biology
2026-06-18
|
#ubiquitination
#protein-protein interaction
#drug design
|
|
0
|
|
Ubiquitin-dependent degradation of p27Kip1 and p21Waf1/Cip1 by AMBRA1 ensures G1 and S phase progression and limits replication stress.
(academic.oup.com)
|
Milletti G
…
Cecconi F
Nucleic Acids Research
2026-06-22
|
#ubiquitination
#cell cycle
#medulloblastoma
#replication stress
#protein degradation
|
|
0
|
|
Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling.
(elifesciences.org)
|
Zacharia NK
…
Lorentzen E
eLife
2026-06-23
|
#ciliogenesis
#ciliopathy
#ubiquitination
#signaling
#protein structure
|
|
0
|
|
The ERAD pathway mediates cross talk between two control points in cholesterol synthesis: HMG CoA reductase and squalene monooxygenase.
(pnas.org)
|
Faulkner RA
…
DeBose-Boyd RA
PNAS
2026-06-23
|
#metabolism
#erad
#proteolysis
#cholesterol
#ubiquitination
|
|
0
|
|
Ubiquitin-like proteins NEDD8 and SUMO2 control epithelial homeostasis, regeneration, and inflammation.
(science.org)
|
Winge MCG
…
Khavari PA
Science
2026-06-25
|
#proteomics
#epithelial
#ubiquitination
#inflammation
#regeneration
|
|
0
|
|
Mechanistic dissection of SMARCA2/4 molecular glues reveals programmable switching between DCAF16 and FBXO22.
(linkinghub.elsevier.com)
|
Rouhimoghadam M
…
Lin X
Cell Chemical Biology
2026-07-02
|
#degradation
#ubiquitination
#proteolysis
#medicinal chemistry
|
|
0
|
|
CDW19S coordinates phasic end processing via distinct enzymatic activities.
(academic.oup.com)
|
Zeng M
…
Liu C
Nucleic Acids Research
2026-07-03
|
#dna repair
#recombination
#ubiquitination
#proteasome
#dsb
|
|
0
|
|
Canonical and phosphoribosyl ubiquitination coordinate to stabilize a proteinaceous structure surrounding the Legionella-containing vacuole.
(elifesciences.org)
|
Steinbach A
…
Mukherjee S
eLife
2026-07-08
|
#ubiquitination
#legionella
#intracellular pathogens
#effector proteins
#host-pathogen-interaction
|
|
0
|
|
Cytoplasmic lattices store developmentally poised degradative and cytoskeletal complexes in mammalian eggs.
(nature.com)
|
Li Y
…
Xiong Y
Nature Structural & Molecular Biology
2026-07-09
|
#embryogenesis
#cryo-em
#ubiquitination
#cytoskeleton
#protein degradation
|
|
0
|
|
DDIT3, OTUB2, and ASS1 regulate arginine biosynthesis in colorectal cancer cells under arginine deficiency.
(linkinghub.elsevier.com)
|
Li M
…
Hou Z
Cell Reports
2026-07-09
|
#colorectal cancer
#metabolism
#ubiquitination
#signaling
|
|
0
|
|
The UFSP2-ODR4 complex spatially confines and dynamically controls UFM1 deconjugation to safeguard neuronal proteostasis.
(linkinghub.elsevier.com)
|
Mao G
…
Komatsu M
Molecular Cell
2026-07-09
|
#proteostasis
#ubiquitination
#neurodegeneration
#endoplasmic-reticulum
|
|
0
|
|
Virome-wide ubiquitin ligase discovery reveals diverse mechanisms of immune evasion.
(science.org)
|
Glassman CR
…
Elledge SJ
Science
2026-07-09
|
#virology
#immunity
#ubiquitination
#proteomics
#evasion
|