|
12
|
|
FBXW5 blunts RIGI/MDA5-IFN signaling to drive immunoevasion and chemo-immune resistance in triple-negative breast cancer models.
(jci.org)
|
Li X
…
Yang Q
Journal of Clinical Investigation
2026-08-25
|
#immunotherapy
#cancer
#ubiquitination
#immunity
#interferon
|
|
10
|
|
Cannabinoid tolerance relies on CB(1) receptor ubiquitination by NEDD4L.
(pnas.org)
|
Alvaro-Blazquez A
…
Guzman M
PNAS
2026-08-25
|
#tolerance
#ubiquitination
#cannabinoids
#desensitization
#receptor
|
|
5
|
|
Autophagy, the Ubiquitin proteasome system, and the MAPK pathway control the temperature dependence of synaptic growth.
(academic.oup.com)
|
De Leon Gonzalez KM
…
Marie B
Genetics
2026-08-25
|
#autophagy
#synaptogenesis
#thermobiology
#ubiquitination
#signaling
|
|
2
|
|
The degrader gets degraded as cysteine fluctuates.
(linkinghub.elsevier.com)
|
Chen J
…
Xiao H
Cell Chemical Biology
2026-08-20
|
#ubiquitination
#proteolysis
#metabolism
|
|
2
|
|
USP14 competitively binds to FBXW7 to stabilize MTDH and promotes metastasis and drug resistance of head and neck squamous cell carcinoma.
(pnas.org)
|
Wang X
…
Liu Y
PNAS
2026-08-19
|
#cancer
#metastasis
#chemoresistance
#ubiquitination
#signaling
|
|
1
|
|
Adipose GGPPS stabilizes BCAT2 to orchestrate BCAA catabolism and lipid mobilization in fasting-induced liver remodeling.
(linkinghub.elsevier.com)
|
Nie HY
…
Fang L
Cell Reports
2026-08-17
|
#metabolism
#fasting
#lipid
#adipose
#ubiquitination
|
|
0
|
|
FAF1 and FAF2 enhance unfolding by p97-UFD1-NPL4 complex enabling rational design of p97 activators.
(link.springer.com)
|
Dasgupta P
…
Kulathu Y
The EMBO Journal
2026-08-15
|
#ubiquitination
#proteolysis
#protein design
#structural biology
|
|
0
|
|
Mechanism of K63-linked polyubiquitin recognition and cleavage by the BRCA1-A complex.
(nature.com)
|
Foglizzo M
…
Zeqiraj E
Nature Communications
2026-08-11
|
#ubiquitination
#deubiquitylation
#dna damage
#protein-protein interaction
#structural biology
|
|
0
|
|
A ubiquitin chain-feeding mechanism for BRCA1-A.
(nature.com)
|
Murachelli AG
…
Sixma TK
Nature Communications
2026-08-11
|
#ubiquitination
#cryo-em
#dna repair
#proteomics
|
|
0
|
|
In-situ cryo-ET of mouse embryos reveals cytoplasmic lattices contain ubiquitin-charged E2-E3 ligase assemblies.
(link.springer.com)
|
Singh K
…
Carter AP
The EMBO Journal
2026-08-10
|
#cryo-em
#ubiquitination
#embryogenesis
#structural biology
#protein complexes
|
|
0
|
|
TRIM29-dependent AKR1B10 degradation ameliorates MASH.
(science.org)
|
Ma Z
…
Ye X
Science Advances
2026-08-07
|
#steatohepatitis
#ubiquitination
#fibrosis
#therapeutics
|
|
0
|
|
DCAF11-dependent molecular glue degrader activated by glutathionylation.
(nature.com)
|
Yoon H
…
Ebert BL
Nature
2026-08-05
|
#proteolysis
#ubiquitination
#protein degradation
#drug discovery
#chemical-screening
|
|
0
|
|
Targeting the E3 ubiquitin ligase RNF10 ameliorates metabolic dysfunction-associated steatohepatitis in mice.
(jci.org)
|
Du C
…
Chang Y
Journal of Clinical Investigation
2026-08-06
|
#steatohepatitis
#ubiquitination
#lipid metabolism
#fibrosis
#rnai
|
|
0
|
|
The E3 ubiquitin ligase LOP1 targets PIF4 to control plant morphogenesis.
(linkinghub.elsevier.com)
|
Song Z
…
Xu D
Current Biology
2026-08-03
|
#ubiquitination
#photomorphogenesis
#protein degradation
#signal transduction
|
|
0
|
|
Ubiquitination plays a key role in an insecticide resistance fitness cost.
(pnas.org)
|
Hu J
…
Yang X
PNAS
2026-07-30
|
#ubiquitination
#insecticide resistance
#fitness-cost
#ptm
|
|
0
|
|
NF-kappaB/RelA signaling required for CD40-induced humoral immunity depends on specific NEMO lysine residues in mice.
(link.springer.com)
|
Li D
…
Miyamoto S
The EMBO Journal
2026-07-30
|
#immunity
#signaling
#b-cells
#ubiquitination
#antibody
|
|
0
|
|
KDM4A promotes microglial pyroptosis and neuropathic pain via the MEG3/SMURF2/HES1 axis.
(academic.oup.com)
|
Wang N
…
Sun X
Journal of Immunology
2026-08-04
|
#pyroptosis
#neuropathic pain
#epigenetics
#microglia
#ubiquitination
|