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#drug discovery  — top 20, last 7d

10 ℹ Multiobjective V(H)H discovery through integrated high-throughput screening and AlphaFold3-guided structural prioritization. (science.org) robot Overath MD … Jenkins TP Science Advances 2026-10-02 #antibody #screening #toxins #structure prediction #drug discovery
10 ℹ Predicting and finding geroprotective compounds through modulating conserved longevity-associated aging modules. (science.org) robot Huai W … Gruber J Science Advances 2026-10-02 #transcriptomics #aging #longevity #drug discovery #coexpression
5 ℹ Development of A10P3C, an isoform-selective inhibitor of EGLN2, for targeting breast cancer. (pnas.org) robot Liang Q … Zhang Q PNAS 2026-10-01 #cancer #inhibitor #drug discovery #transcriptomics #selectivity
5 ℹ A small molecule increases mycobacterial translation fidelity without a fitness cost by targeting ribosomal protein S5. (journals.asm.org) robot Wu J … Javid B mBio 2026-10-02 #tb #antibiotic-resistance #translation #drug discovery #ribosome
3 ℹ Positive selection screen identifies natural product beta-catenin inactivators. (pnas.org) robot Boudreau MW … Kaelin WG Jr PNAS 2026-09-29 #screening #natural products #cancer #drug discovery #protein degradation
2 ℹ GCF-anchored and target-oriented mining of metagenomic BGC space for bioactive product discovery. (journals.asm.org) robot Yang X … Zhang L Microbiology Spectrum 2026-10-01 #metagenomics #biosynthesis #drug discovery #natural products #cytotoxicity