|
14
|
|
Targeting SUV39H2 exon skipping reverses resistance to CDK4/6 inhibitors via transcriptional activation of p21.
(science.org)
|
Yu S
…
Sun H
Science Advances
2026-10-09
|
#splicing
#breast cancer
#drug resistance
#epigenetics
#senescence
|
|
14
|
|
Senescent tumor cell membrane-based "time engine" nanosystem amplifies endoplasmic reticulum targeting for metastasis blockade.
(science.org)
|
Tao J
…
Huang Y
Science Advances
2026-10-09
|
#nanotechnology
#drug delivery
#cancer
#senescence
#immunotherapy
|
|
4
|
|
Late-onset preeclampsia is characterized by accelerated placental aging.
(pnas.org)
|
Arthurs AL
…
Roberts CT
PNAS
2026-10-06
|
#placenta
#preeclampsia
#oxidative stress
#senescence
#organoid
|
|
2
|
|
Glucose-deprived tumor microenvironment activates AMP-activated protein kinase to drive adoptively transferred T helper 9 cell senescence.
(linkinghub.elsevier.com)
|
Fu J
…
Xiao Y
Immunity
2026-10-01
|
#immunotherapy
#senescence
#tumor microenvironment
#metabolism
#car-t
|
|
2
|
|
Senolytics dasatinib and quercetin in metabolic dysfunction-associated steatohepatitis: a proof-of-principle randomized, controlled trial.
(nature.com)
|
Koning M
…
Meijnikman AS
Nature Metabolism
2026-10-01
|
#steatohepatitis
#senolytic
#senescence
#fibrosis
#transcriptomics
|
|
1
|
|
Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism.
(elifesciences.org)
|
Deng F
…
Zhang L
eLife
2026-10-08
|
#metabolism
#aging
#epigenetics
#mitochondrial
#senescence
|
|
1
|
|
Cellular senescence: six decades of discovery and reinvention.
(link.springer.com)
|
Klaver M
…
Demaria M
The EMBO Journal
2026-10-02
|
#senescence
#aging
#therapeutics
#tumor suppression
#biomarker
|
|
0
|
|
Senescence-directed nanotherapy ameliorates fibrosis and overcomes immune exclusion in cancer.
(science.org)
|
Hinterleitner C
…
Lowe SW
Science
2026-09-24
|
#senescence
#fibrosis
#nanotherapy
#cancer
#immunotherapy
|
|
0
|
|
A liver-cartilage selenium axis underlies metabolic comorbidity in osteoarthritis.
(linkinghub.elsevier.com)
|
Yong S
…
Kim JH
Cell Metabolism
2026-09-22
|
#osteoarthritis
#metabolism
#selenoproteins
#senescence
#liver
|
|
0
|
|
Quantitative proteomics reveals coordinated changes in the proteome during replicative senescence.
(nature.com)
|
Da Silva Fernandes N
…
Beli P
Nature Communications
2026-09-16
|
#proteomics
#senescence
#proteostasis
#aging
#autophagy
|
|
0
|
|
Endothelial C/EBPbeta/AEP pathway drives vascular deterioration and systemic aging.
(science.org)
|
Li B
…
Ye K
Science Advances
2026-09-16
|
#aging
#endothelium
#senescence
#metabolism
#proteolysis
|
|
0
|
|
LSD1-mediated demethylation of the DNA damage response factor ATM promotes senescence and organ aging.
(jci.org)
|
Zhang Y
…
Li X
Journal of Clinical Investigation
2026-09-15
|
#aging
#senescence
#epigenetics
#dna damage
#autophagy
|
|
0
|
|
Discovery of a small peptide that increases yeast lifespan by enhancing the function of APCCdh1 in nondividing quiescent cells.
(academic.oup.com)
|
Harris RE
…
Harkness TAA
Genetics
2026-09-16
|
#aging
#senescence
#lifespan
#peptide
#yeast
|