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0
|
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Customizing the structure of minimal TIM barrels to craft efficient de novo enzymes.
(nature.com)
|
Beck J
…
Hocker B
Nature Chemical Biology
2026-06-15
|
#protein design
#computational modeling
#catalysis
#enzyme design
|
|
0
|
|
Void-X: A generative void-filling model for predicting atomic packing in proteins.
(pnas.org)
|
Yang J
…
Chou JJ
PNAS
2026-06-16
|
#protein design
#diffusion models
#structure prediction
#deep learning
#protein-protein interaction
|
|
0
|
|
Directed evolution of compact RNA-guided nucleases for enhanced activity in mammalian cells.
(link.springer.com)
|
Gorbenko F
…
Corn JE
Genome Biology
2026-06-16
|
#protein design
#directed evolution
#genome editing
#cas nucleases
|
|
0
|
|
Computational design and cellular synthesis of two protein topological isomers: Solomon link vs. three-twist knot.
(pnas.org)
|
Xu L
…
Zhang WB
PNAS
2026-06-23
|
#computational design
#topology
#stability
#protein design
|
|
0
|
|
Efficient generation of epitope-targeted antibodies with Germinal.
(nature.com)
|
Mille-Fragoso LS
…
Gao XJ
Nature Biotechnology
2026-06-23
|
#antibody
#computational design
#protein design
#generative_models
#epitope
|
|
0
|
|
Zero-shot design of drug-binding proteins via neural iterative selection-expansion.
(nature.com)
|
Fry B
…
Polizzi NF
Nature
2026-06-24
|
#protein design
#deep learning
#drug binding
#neural network
#structure prediction
|
|
0
|
|
Design optimization of antibody-ligand motifs to enhance CAR-T redirection activity against solid tumors.
(linkinghub.elsevier.com)
|
Wang X
…
Cao YJ
Cell Reports Medicine
2026-06-25
|
#immunotherapy
#car-t
#cancer
#protein design
#tumor microenvironment
|
|
0
|
|
Deciphering key factors of active learning performance in biomolecular design.
(academic.oup.com)
|
Zhi Y
…
Wang X
Bioinformatics
2026-07-01
|
#machine learning
#active learning
#protein design
#optimization
#genetic engineering
|
|
0
|
|
Agentomics: an agentic system that autonomously develops novel state-of-the-art solutions for biomedical machine learning tasks.
(academic.oup.com)
|
Martinek V
…
Alexiou P
Bioinformatics
2026-07-01
|
#machine learning
#automation
#drug discovery
#genomics
#protein design
|
|
0
|
|
USP-ddG: a unified structural paradigm with data efficacy and mixture-of-experts for predicting mutational effects on protein-protein interactions.
(academic.oup.com)
|
Yu G
…
Wang J
Bioinformatics
2026-07-01
|
#protein-protein interaction
#protein design
#deep learning
#structural prediction
#binding-energy
|
|
0
|
|
Beyond native sequence recovery: Improved modeling of the sequence-energy landscape of protein structures.
(pnas.org)
|
Birnbaum F
…
Keating AE
PNAS
2026-07-02
|
#protein design
#sequence modeling
#machine learning
#structure prediction
#computational biology
|
|
0
|
|
Membrane protein solubilization and structure determination using de novo-designed proteins.
(science.org)
|
Mihaljevic L
…
Baker D
Science
2026-07-02
|
#membrane proteins
#protein design
#cryo-em
#structure determination
#vaccine-development
|
|
0
|
|
Artificial metalloenzymes in complex biological environments.
(nature.com)
|
Rhys GG
Nature Chemical Biology
2026-07-03
|
#metalloenzymes
#protein design
#catalysis
#biocompatibility
|
|
0
|
|
Liquid-liquid phase separation enables chromatography-free purification and high-performance spidroin-amyloid hybrid silk fibers.
(pnas.org)
|
Tufvesson K
…
Schmuck B
PNAS
2026-07-08
|
#protein design
#purification
#phase separation
#recombinant-proteins
#biomaterials
|
|
0
|
|
Mind the gap: An embedding guide to safely travel in sequence space.
(journals.plos.org)
|
Wu A
…
Angioletti-Uberti S
PLOS Computational Biology
2026-07-09
|
#protein design
#mutagenesis
#enzyme design
#machine learning
#computational biology
|
|
0
|
|
FDA-approved fulvestrant-induced CAR phase separation enables precise control of CAR T antitumor function.
(linkinghub.elsevier.com)
|
Huang Y
…
Wang H
Cell Stem Cell
2026-07-10
|
#car-t
#immunotherapy
#cancer
#phase separation
#protein design
|