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23
|
|
De novo design of cysteine proteases.
(nature.com)
|
Choi H
…
Baker D
Nature
2026-10-14
|
#proteolysis
#enzyme design
#catalysis
#protein design
#synthetic biology
|
|
15
|
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HURDLER: a cloning method to overcome length limits in designed repeat proteins.
(academic.oup.com)
|
Dai W
…
Zerbe O
Nucleic Acids Research
2026-10-13
|
#protein design
#cloning
#synthetic biology
#directed evolution
|
|
7
|
|
Structural basis and rational engineering of a thermophilic Cas13a for robust RNA detection.
(linkinghub.elsevier.com)
|
Oladeji SJ
…
Gao Y
Cell Chemical Biology
2026-10-13
|
#crispr
#rna
#diagnostics
#protein design
#structural biology
|
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4
|
|
Design of ancestral protein-glutaminase with improved thermal stability.
(journals.asm.org)
|
Ono T
…
Nakano S
Applied and Environmental Microbiology
2026-10-13
|
#protein design
#thermostability
#ancestral reconstruction
#enzyme
|
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4
|
|
A bifunctional actuator to correct loss-of-function deficits in cardiac voltage-gated sodium channels.
(science.org)
|
Fossier L
…
Ben-Johny M
Science Advances
2026-10-09
|
#ion channel
#channelopathy
#arrhythmia
#cardiac
#protein design
|
|
2
|
|
Use of split intein and myotropic AAV vectors enables effective preclinical gene therapy for dysferlinopathy.
(science.org)
|
McCormack NM
…
Tasfaout H
Science Translational Medicine
2026-10-07
|
#gene therapy
#muscular dystrophy
#aav vectors
#protein design
#muscle-disease
|
|
2
|
|
Machine learning-assisted directed evolution of plant Rubisco.
(science.org)
|
McDonald JL
…
Wilson RH
Science Advances
2026-10-07
|
#protein design
#directed evolution
#machine learning
#enzyme kinetics
|
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1
|
|
DeepSAP: An Integrated Generative and Predictive Deep-Learning Framework for Controllable Design of Self-Assembling Peptides.
(academic.oup.com)
|
Song Y
…
Deng X
Bioinformatics
2026-10-07
|
#deep learning
#peptide
#self-assembly
#protein design
#generative modeling
|
|
1
|
|
DyME: An MD-based engine exploiting HTP mutagenesis for protein engineering and recognition mimicry.
(journals.plos.org)
|
Guillem-Gloria PM
…
Pisabarro MT
PLOS Computational Biology
2026-10-07
|
#mutagenesis
#simulation
#protein design
#binding
#computational
|
|
0
|
|
Function-preserving watermarking of AI-generated proteins.
(nature.com)
|
Stutz D
…
Kohli P
Nature
2026-09-30
|
#protein design
#watermarking
#ai
#provenance
#biosecurity
|
|
0
|
|
Advances in amidases and urethanases as depolymerization biocatalysts.
(nature.com)
|
Bayer T
…
Bornscheuer UT
Nature Chemical Biology
2026-10-01
|
#biocatalysis
#depolymerization
#protein design
#hydrolase
#metagenomics
|
|
0
|
|
FLIGHTED: Inferring fitness landscapes from noisy high-throughput experimental data.
(linkinghub.elsevier.com)
|
Sundar V
…
Esvelt K
Cell Systems
2026-10-02
|
#machine learning
#protein design
#high-throughput
#fitness-landscapes
#bayesian
|
|
0
|
|
Receptor-tuned Interleukin-2 Mutein Decouples Treg Expansion from ILC2-driven Cutaneous Inflammation.
(jci.org)
|
Sahoo A
…
Deng W
Journal of Clinical Investigation
2026-09-29
|
#immunotherapy
#autoimmunity
#inflammation
#innate immunity
#protein design
|
|
0
|
|
StrucNS reveals interaction-weighted network topology as the driving predictor of absolute stability of natural and de novo proteins.
(academic.oup.com)
|
Mullick A
…
Hackel BJ
Bioinformatics
2026-09-30
|
#protein stability
#protein design
#structure prediction
#machine learning
#network-topology
|
|
0
|
|
A method for expressing two proteins at a tunable ratio allows for studying the kinetics of creatine transport by MCT12.
(linkinghub.elsevier.com)
|
Boytsov D
…
Roblek M
iScience
2026-09-30
|
#protein design
#transport
#expression
#stoichiometry
|
|
0
|
|
A designed ubiquitin-binding protein selectively enriches and visualizes unanchored ubiquitin.
(science.org)
|
Shi S
…
Wang L
Science Advances
2026-09-25
|
#ubiquitination
#protein design
#proteomics
|
|
0
|
|
Simplifying in silico protein evolution with minimal screening by unZipro.
(linkinghub.elsevier.com)
|
Qin Z
…
Ji X
Molecular Cell
2026-09-24
|
#protein design
#machine learning
#directed evolution
#biotechnology
|
|
0
|
|
Generative AI designs functional thiolation domains for reprogramming non-ribosomal peptide synthetases.
(nature.com)
|
Bulbul EF
…
Bozhuyuk KAJ
Nature Communications
2026-09-22
|
#biosynthesis
#protein design
#machine learning
#enzyme-engineering
#synthetic biology
|
|
0
|
|
Computational design of optimized and preferentially paired human TCR constant regions for improved T cell function.
(science.org)
|
Radman M
…
Cohen CJ
Science Advances
2026-09-23
|
#immunotherapy
#protein design
#t cell
#cancer
#computational design
|
|
0
|
|
Engineering plant tandem kinase immune receptors expands effector recognition profiles.
(science.org)
|
Yu DS
…
Banfield MJ
Science Advances
2026-09-23
|
#immunity
#protein design
#plant-pathology
#structural biology
#effector-recognition
|