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23
|
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Molecular functions, cellular responses and pathological implications of the RNA modification N(6)-methyladenosine.
(nature.com)
|
Kang Z
…
Liu J
Nature Reviews Molecular Cell Biology
2026-10-22
|
#epigenomics
#methylation
#cancer
#immunity
#neurodegeneration
|
|
10
|
|
Cytokine circuits in CNS homeostasis and disease.
(nature.com)
|
Becher B
…
Greter M
Nature Immunology
2026-10-23
|
#cytokine
#neuroinflammation
#immunity
#neurodegeneration
#microglia
|
|
9
|
|
Tau isoform mapping across tissues and biofluids reveals a signature distinguishing Alzheimer's disease from amyotrophic lateral sclerosis.
(nature.com)
|
Abu-Rumeileh S
…
Otto M
Nature Communications
2026-10-22
|
#neurodegeneration
#biomarker
#proteomics
|
|
9
|
|
BCG vaccination mitigates tau pathology and restores cognitive function in PS19 mice.
(science.org)
|
Shee S
…
Bishai W
Science Advances
2026-10-23
|
#tauopathy
#vaccination
#neurodegeneration
#neuroinflammation
#transcriptomics
|
|
7
|
|
Cold activates a BH2 metabolic network promoting longevity and proteostasis.
(nature.com)
|
Lee HJ
…
Vilchez D
Nature
2026-10-21
|
#proteostasis
#longevity
#metabolism
#aging
#neurodegeneration
|
|
6
|
|
Cas9 nickase-mediated contraction of CAG/CTG repeats is associated with phenotypic improvements in a Huntington's disease mouse model.
(science.org)
|
Murillo A
…
Dion V
Science Translational Medicine
2026-10-21
|
#crispr
#neurodegeneration
#gene therapy
#repeat expansion
|
|
4
|
|
HAP40 functions as a proteostasis regulator by controlling huntingtin interactions and its release into the extracellular space.
(pnas.org)
|
Silva Ramos E
…
Wanker EE
PNAS
2026-10-22
|
#proteostasis
#huntingtin
#autophagy
#proteotoxicity
#neurodegeneration
|
|
3
|
|
Translational control of microglial metabolism, inflammatory responses, and survival by the eIF4E-binding proteins.
(pnas.org)
|
Bermudez S
…
Sonenberg N
PNAS
2026-10-21
|
#neurodegeneration
#neuroinflammation
#microglia
#translational control
#mtor
|
|
3
|
|
Emerging links between gut dysbiosis, aryl hydrocarbon receptor activation, and Parkinson's disease.
(nature.com)
|
Aziz NF
…
Kortagere S
Communications Biology
2026-10-22
|
#dysbiosis
#neurodegeneration
#metabolism
#inflammation
#gut-brain axis
|
|
3
|
|
Lipid-fuelled synaptic plasticity: integrating membrane turnover, beta-oxidation, and protein lipidation.
(link.springer.com)
|
Saber SH
…
Meunier FA
The EMBO Journal
2026-10-21
|
#lipid metabolism
#synaptic plasticity
#beta-oxidation
#protein-lipidation
#neurodegeneration
|
|
3
|
|
Cerebrospinal fluid amyloid and neurodegeneration biomarkers in the diagnosis and prognosis of amyotrophic lateral sclerosis: a multicohort observational study.
(linkinghub.elsevier.com)
|
Obara K
…
Mattsson-Carlgren N
EBioMedicine
2026-10-20
|
#neurodegeneration
#biomarker
#cerebrospinal fluid
#machine learning
|
|
2
|
|
CX3CL1 (fractalkine)-CX3CR1 interface drives CD8(+) T cell-induced neurodegeneration in human brain organoids.
(pnas.org)
|
Yang WS
…
Kang I
PNAS
2026-10-20
|
#neurodegeneration
#neuroinflammation
#immunity
#organoid
#cytotoxicity
|
|
2
|
|
Heterogeneous amyloid beta dimerization revealed by single-molecule FRET and MD simulation.
(pnas.org)
|
Meng F
…
Chung HS
PNAS
2026-10-20
|
#amyloid
#aggregation
#fret
#simulation
#neurodegeneration
|
|
1
|
|
An integrated human forebrain organoid reveals microglia-mediated CD8(+) T cell recruitment and neuroimmune dysfunction in Alzheimer's disease pathology.
(elifesciences.org)
|
Feng Y
…
Ma S
eLife
2026-10-20
|
#neurodegeneration
#neuroinflammation
#organoid
#immunity
#microglia
|