|
23
|
|
Molecular functions, cellular responses and pathological implications of the RNA modification N(6)-methyladenosine.
(nature.com)
|
Kang Z
…
Liu J
Nature Reviews Molecular Cell Biology
2026-10-22
|
#epigenomics
#cancer
#methylation
#immunity
#neurodegeneration
|
|
10
|
|
Cytokine circuits in CNS homeostasis and disease.
(nature.com)
|
Becher B
…
Greter M
Nature Immunology
2026-10-23
|
#cytokine
#neuroinflammation
#immunity
#neurodegeneration
#microglia
|
|
9
|
|
Tau isoform mapping across tissues and biofluids reveals a signature distinguishing Alzheimer's disease from amyotrophic lateral sclerosis.
(nature.com)
|
Abu-Rumeileh S
…
Otto M
Nature Communications
2026-10-22
|
#biomarker
#neurodegeneration
#proteomics
|
|
9
|
|
BCG vaccination mitigates tau pathology and restores cognitive function in PS19 mice.
(science.org)
|
Shee S
…
Bishai W
Science Advances
2026-10-23
|
#tauopathy
#neuroinflammation
#vaccination
#neurodegeneration
#transcriptomics
|
|
7
|
|
Cold activates a BH2 metabolic network promoting longevity and proteostasis.
(nature.com)
|
Lee HJ
…
Vilchez D
Nature
2026-10-21
|
#longevity
#proteostasis
#metabolism
#aging
#neurodegeneration
|
|
6
|
|
Cas9 nickase-mediated contraction of CAG/CTG repeats is associated with phenotypic improvements in a Huntington's disease mouse model.
(science.org)
|
Murillo A
…
Dion V
Science Translational Medicine
2026-10-21
|
#crispr
#neurodegeneration
#gene therapy
#repeat expansion
|
|
4
|
|
HAP40 functions as a proteostasis regulator by controlling huntingtin interactions and its release into the extracellular space.
(pnas.org)
|
Silva Ramos E
…
Wanker EE
PNAS
2026-10-22
|
#proteostasis
#huntingtin
#autophagy
#proteotoxicity
#neurodegeneration
|
|
3
|
|
Translational control of microglial metabolism, inflammatory responses, and survival by the eIF4E-binding proteins.
(pnas.org)
|
Bermudez S
…
Sonenberg N
PNAS
2026-10-21
|
#neuroinflammation
#microglia
#neurodegeneration
#translational control
#mtor
|
|
3
|
|
Emerging links between gut dysbiosis, aryl hydrocarbon receptor activation, and Parkinson's disease.
(nature.com)
|
Aziz NF
…
Kortagere S
Communications Biology
2026-10-22
|
#dysbiosis
#neurodegeneration
#metabolism
#gut-brain axis
#inflammation
|
|
3
|
|
Lipid-fuelled synaptic plasticity: integrating membrane turnover, beta-oxidation, and protein lipidation.
(link.springer.com)
|
Saber SH
…
Meunier FA
The EMBO Journal
2026-10-21
|
#synaptic plasticity
#lipid metabolism
#beta-oxidation
#protein-lipidation
#neurodegeneration
|
|
3
|
|
Cerebrospinal fluid amyloid and neurodegeneration biomarkers in the diagnosis and prognosis of amyotrophic lateral sclerosis: a multicohort observational study.
(linkinghub.elsevier.com)
|
Obara K
…
Mattsson-Carlgren N
EBioMedicine
2026-10-20
|
#biomarker
#neurodegeneration
#cerebrospinal fluid
#machine learning
|
|
2
|
|
CX3CL1 (fractalkine)-CX3CR1 interface drives CD8(+) T cell-induced neurodegeneration in human brain organoids.
(pnas.org)
|
Yang WS
…
Kang I
PNAS
2026-10-20
|
#neurodegeneration
#neuroinflammation
#organoid
#immunity
#cytotoxicity
|
|
2
|
|
Heterogeneous amyloid beta dimerization revealed by single-molecule FRET and MD simulation.
(pnas.org)
|
Meng F
…
Chung HS
PNAS
2026-10-20
|
#amyloid
#aggregation
#fret
#simulation
#neurodegeneration
|
|
1
|
|
PTPRS mediates invasion of tetanus neurotoxin into the central nervous system.
(linkinghub.elsevier.com)
|
Chen P
…
Dong M
Cell
2026-10-13
|
#toxins
#retrograde-transport
#neurodegeneration
#protein-interactions
#cns
|
|
1
|
|
Genome-wide CRISPR screen reveals that Wnt signaling regulates lipid accumulation in APOE4 oligodendrocytes.
(linkinghub.elsevier.com)
|
Akay LA
…
Tsai LH
Cell Stem Cell
2026-10-15
|
#crispr
#neurodegeneration
#myelination
#lipid
#signaling
|
|
1
|
|
Noninvasive ultrashort wave neuromodulation enhances glymphatic clearance to alleviate traumatic brain edema and Alzheimer's pathology.
(science.org)
|
Liu J
…
Peng N
Science Advances
2026-10-16
|
#neuromodulation
#glymphatic
#neuroprotection
#neurodegeneration
#neuroinflammation
|
|
1
|
|
Escherichia coli hns and methylglyoxal link gut microbial metabolism to host neuronal gene regulation in Parkinson's disease.
(tandfonline.com)
|
Shin MG
…
Lee EJ
Gut Microbes
2026-10-15
|
#microbiome
#neurodegeneration
#metabolism
#transcriptomics
|
|
1
|
|
Preclinical and first-in-human evaluation of VG-3927/SAR448851, an oral small-molecule TREM2 agonist for Alzheimer's disease.
(science.org)
|
Dejanovic B
…
Mirescu C
Science Translational Medicine
2026-10-14
|
#neurodegeneration
#microglia
#immunotherapy
#neuroinflammation
#drug development
|
|
1
|
|
Edited HSPCs rescue frataxin deficiency and inflammation-driven multisystemic pathology in Friedreich's ataxia mice.
(jci.org)
|
Sivakumar A
…
Cherqui S
Journal of Clinical Investigation
2026-10-15
|
#crispr
#gene therapy
#neurodegeneration
#mitochondrial
#inflammation
|
|
1
|
|
Modeling human neurodegeneration with iPSCs: opportunities, limitations, and the challenge of aging.
(jci.org)
|
Wang S
…
Finkbeiner S
Journal of Clinical Investigation
2026-10-15
|
#neurodegeneration
#ipscs
#organoid
#aging
#epigenetics
|