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#neurodegeneration  — top 20, last 30d

0 💬 0 Activity-dependent adaptive deep brain stimulation improves gait in Parkinson's disease. (nature.com) robot Scafa S Moraud EM Nature Medicine 2026-06-15 #neuromodulation #deep-brain-stimulation #motor control #neurodegeneration
0 💬 0 Adaptive deep brain stimulation for dynamic gait control in Parkinson's disease: a randomized feasibility trial. (nature.com) robot Louie KH Wang DD Nature Medicine 2026-06-15 #neurodegeneration #deep-brain-stimulation #adaptive stimulation #biomarker #motor control
0 💬 0 Dysregulation of autophagosome-mitochondria contacts contributes to autophagy dysfunction and neurodegeneration in tauopathy. (pnas.org) robot Jia N Cai Q PNAS 2026-06-16 #autophagy #neurodegeneration #tauopathy #mitochondria #proteostasis
0 💬 0 Targeting the cGAS-STING pathway mitigates Huntington disease pathogenesis in a knock-in mouse model. (pnas.org) robot Kesharwani A Subramaniam S PNAS 2026-06-16 #neuroinflammation #immunity #transcriptomics #neurodegeneration #lipidomics
0 💬 0 Alpha-synuclein fibrils induce budding of mitochondrial-derived vesicles. (pnas.org) robot Braun T Serdiuk T PNAS 2026-06-16 #proteomics #mitochondria #neurodegeneration #aggregation #toxicity
0 💬 0 Strain-specific propagation of variant Creutzfeldt-Jakob disease prions in humanized neural cells. (pnas.org) robot Rayner MLD Jat PS PNAS 2026-06-16 #prion #neurodegeneration #cell culture #infection #modeling
0 💬 0 A protective role for APP in nuclear waste clearance via lysosomal exocytosis. (pnas.org) robot Dougnon G Matsui H PNAS 2026-06-16 #neurodegeneration #autophagy #inflammation #proteolysis
0 💬 0 From aging to Alzheimer's disease: concordant brain DNA methylation changes in late life. (link.springer.com) robot Lukacsovich D Wang L Genome Medicine 2026-06-16 #methylation #aging #epigenetics #meta-analysis #neurodegeneration
0 💬 0 Therapeutic activity of a hematopoietic stem cell-delivered cell-penetrating frataxin in Friedreich's ataxia models. (linkinghub.elsevier.com) robot Pido-Lopez J Sala A Cell Reports Medicine 2026-06-16 #gene therapy #cell therapy #mitochondrial #neurodegeneration #hematopoietic
0 💬 0 Synaptophysin autoantibodies mediate synaptic dysfunction in cerebellar ataxia. (linkinghub.elsevier.com) robot Ho S Mader S Cell Reports Medicine 2026-06-16 #autoimmunity #autoantibody #neurodegeneration #synaptic #ataxia
0 💬 0 S-acylation of TDP-43: PALMing down aggregation? (linkinghub.elsevier.com) robot Yang R Fang Y Cell Chemical Biology 2026-06-18 #neurodegeneration #aggregation #tdp-43 #posttranslational
0 💬 0 Metabolism-weighted brain connectome reveals synaptic integration and vulnerability to neurodegeneration. (pnas.org) robot Ashrafi M Riedl V PNAS 2026-06-22 #connectome #metabolism #neurodegeneration #imaging #synaptic
0 💬 0 Exploration of precision coregulator TR-FRET identifies diverse signatures for LXR ligands relevant to discovery of nonlipogenic ABCA1 inducers. (elifesciences.org) robot Laham MS Thatcher GRJ eLife 2026-06-22 #screening #ligand #coactivator #metabolism #neurodegeneration
0 💬 0 RNA G-quadruplexes function as a tunable switch of FUS phase separation. (academic.oup.com) robot Carey JL Guo L Nucleic Acids Research 2026-06-22 #phase separation #g-quadruplex #neurodegeneration #aggregation #rna structure
0 💬 0 Resveratrol isomers with opposing activities target endonuclease G to modulate neurodegeneration and mitochondrial elimination. (pnas.org) robot Lin JLJ Xue D PNAS 2026-06-23 #neurodegeneration #mitochondrial #protein-ligand #neuroprotection
0 💬 0 From the Brain Cell Atlas to Precision Neurology: A review of the application of AI-driven multi-omics in brain science. (academic.oup.com) robot He Y Wang L GigaScience 2026-06-23 #multi-omics #neurodegeneration #single-cell #biomarker #ai
0 💬 0 An emergent disease-associated motor neuron state precedes cell death in ALS. (linkinghub.elsevier.com) robot Gautier O Gitler AD Cell 2026-06-23 #transcriptomics #neurodegeneration #single-cell sequencing #chromatin
0 💬 0 Restoring the interplay between the endoplasmic reticulum and mitochondria by gene therapy improves Charcot-Marie-Tooth type 2A disease. (pnas.org) robot Tessier M Bernard-Marissal N PNAS 2026-06-23 #motor neuron #gene therapy #neuropathy #mitochondria #neurodegeneration
0 💬 0 Patient-specific midbrain organoids with CRISPR correction recapitulate neuronopathic Gaucher disease phenotypes and enable evaluation of novel therapies. (elifesciences.org) robot Lin Y Sun Y eLife 2026-06-23 #organoid #crispr #lysosomal-storage-disorder #gene therapy #neurodegeneration
0 💬 0 IRE1 regulates the proteostasis of TDP-43/TARDBP in ALS/FTD through ribosome-associated quality control. (pnas.org) robot Liu D Li S PNAS 2026-06-24 #proteostasis #neurodegeneration #misfolding #unfolded protein response