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21
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Cross-species single-cell atlas of the striatum defines cell-type and subregion disease vulnerabilities.
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Linville RM
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Heiman M
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2026-09-01
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19
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Natural history and clinical impact of epilepsy in adults with Down syndrome: a multicentre clinical study.
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Maure-Blesa L
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Fortea J
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2026-09-03
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18
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APOE4 astrocytes call the shots on neuronal alpha-synuclein pathology.
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West NR
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2026-09-03
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16
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Activation of transposable elements is linked to a region- and cell type-specific interferon response in Parkinson's disease.
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Garza R
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Jakobsson J
Science Advances
2026-09-04
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7
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Solute carrier membrane transporters: emerging targets in CNS disorders.
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Law YK
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Nature Reviews Drug Discovery
2026-09-01
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5
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Mitophagy in neuronal health and disease: from mechanisms to neurodegeneration.
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Basak B
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Holzbaur EL
Journal of Clinical Investigation
2026-09-01
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4
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Presynaptic accumulation of APP-CTFbeta may contribute to synaptic dysfunction in Alzheimer's disease.
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Kapadia A
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Hafner AS
The EMBO Journal
2026-09-01
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4
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Repositioning of polyubiquitin alters the pathologic tau filament structure.
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Watanabe R
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Lee EB
Nature Structural & Molecular Biology
2026-08-31
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4
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Plasma neurofilament light for early differentiation of multiple system atrophy from Parkinson disease.
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Yu Z
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Feng T
EBioMedicine
2026-08-31
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3
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Immune-mediated excitotoxicity in brain disorders.
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Shin J
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Zipp F
Nature Reviews Immunology
2026-08-27
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#neuroinflammation
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2
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A multiancestry polygenic risk score for Alzheimer's disease is associated with cognitive decline and neuropathological hallmarks in diverse populations.
(nature.com)
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Kurniansyah N
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Farrer LA
Nature Genetics
2026-08-27
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2
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Differential associations of tau extent and load with brain metabolic and cognitive dysfunction in Alzheimer's disease.
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Macedo AC
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Rosa-Neto P
EBioMedicine
2026-08-29
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2
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Neuron-derived SPP1 instructs microglia to limit degeneration.
(science.org)
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Li S
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Jakobs TC
Science Advances
2026-08-28
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2
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Oligodendrocyte dysfunction in human age-related cognitive decline.
(nature.com)
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Craig GA
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Miron VE
Nature Medicine
2026-08-25
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2
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Senescent cells maintain viability through adhesion-dependent fragmentation that promotes debris deposition.
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Durik M
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Keyes WM
Developmental Cell
2026-08-28
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2
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Aberrant excitatory neuronal ERBB4 promotes Alzheimer's disease pathology.
(nature.com)
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Lee SY
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Chung WS
Nature
2026-08-26
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#neurodegeneration
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1
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A 3D human retina model reveals a non-cell-autonomous and non-neuronal mechanism of photoreceptor loss in a lysosomal storage disorder.
(science.org)
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Han J
…
Singh R
Science Translational Medicine
2026-08-26
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#organoid
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1
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Next-generation multiplexed targeted proteomics quantifies post-translational modifications in disease and compound-protein interactions with high throughput.
(nature.com)
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Shuken SR
…
Yu Q
Nature Communications
2026-08-25
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1
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Loss of laminin-gamma1 in pericytes impairs microvascular function and cognition.
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Ruan J
…
Yao Y
Cell Reports
2026-08-27
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1
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Cholesterol dysregulation in APOE4 astrocytes promotes alpha-synuclein pathology in miBrains.
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Mesentier-Louro LA
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Blanchard JW
Cell Stem Cell
2026-08-24
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#neurodegeneration
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