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6
|
|
Interbacterial competition triggers stress-induced CRISPR immunity against bacteriophages.
(linkinghub.elsevier.com)
|
Custodio R
…
Westra ER
Current Biology
2026-10-20
|
#crispr
#phage
#immunity
#competition
#microbiome
|
|
4
|
|
Genome-wide CRISPR screen reveals that Wnt signaling regulates lipid accumulation in APOE4 oligodendrocytes.
(linkinghub.elsevier.com)
|
Akay LA
…
Tsai LH
Cell Stem Cell
2026-10-15
|
#crispr
#neurodegeneration
#myelination
#lipid
#signaling
|
|
4
|
|
A Novel CCMS Model Reveals a Critical Intronic Sequence in the Snrpb Gene that is Required for Normal Development.
(academic.oup.com)
|
Beauchamp MC
…
Jerome-Majewska LA
Genetics
2026-10-20
|
#splicing
#developmental
#craniofacial
#crispr
#genetic
|
|
4
|
|
Chemogenetic ubiquitin E1 inhibitor TAK-243 CRISPR screen uncovers HAPSTR1/HUWE1 axis in chromatin proteostasis and cell cycle control.
(science.org)
|
van Overbeek NK
…
Vertegaal ACO
Science Advances
2026-10-16
|
#crispr
#ubiquitination
#proteostasis
#cell cycle
#cancer
|
|
4
|
|
Programmable and selective silencing of oncogenic fusion transcripts by CRISPR-Cas13b via breakpoint sequence recognition.
(science.org)
|
Hu 胡文欣 W
…
Fareh M
Science Advances
2026-10-16
|
#crispr
#fusion
#cancer
#leukemia
#transcriptomics
|
|
3
|
|
Elp1 is required for myeloid differentiation and brain repopulation.
(nature.com)
|
Mader MM
…
Wernig M
Nature
2026-10-14
|
#hematopoiesis
#differentiation
#transplantation
#microglia
#crispr
|
|
3
|
|
Beyond prediction: The evolving role of artificial intelligence in genome editing.
(linkinghub.elsevier.com)
|
Shin S
…
Bae S
Molecular Cell
2026-10-15
|
#crispr
#ai
#genome editing
#machine learning
#protein design
|
|
3
|
|
A conserved Hox9-10 code underlies the early establishment of hind appendage progenitors in zebrafish and the Iberian ribbed newt.
(pnas.org)
|
Nakazawa H
…
Kawamura A
PNAS
2026-10-16
|
#developmental biology
#hox-genes
#appendage-development
#vertebrate-evolution
#crispr
|
|
2
|
|
Single-cell CRISPR screen maps epigenetic regulators of lineage specification and malignancies in human HSPCs.
(linkinghub.elsevier.com)
|
Yuan S
…
Cheng T
Cell Stem Cell
2026-10-13
|
#crispr
#epigenetics
#single-cell
#hematopoiesis
#leukemia
|
|
2
|
|
Edited HSPCs rescue frataxin deficiency and inflammation-driven multisystemic pathology in Friedreich's ataxia mice.
(jci.org)
|
Sivakumar A
…
Cherqui S
Journal of Clinical Investigation
2026-10-15
|
#crispr
#gene therapy
#mitochondrial
#neurodegeneration
#inflammation
|
|
2
|
|
Cells heal themselves: gene-edited hematopoietic stem cells restore frataxin deficiency in multiple organs.
(jci.org)
|
Osborne LR
Journal of Clinical Investigation
2026-10-15
|
#genome editing
#stem-cells
#friedreich-ataxia
#crispr
#mitochondrial
|
|
2
|
|
CRISPR-mediated gap-based replacement enables site-specific DNA lesion insertion into long DNA and nucleosomes.
(academic.oup.com)
|
Kim Y
…
Lee JY
Nucleic Acids Research
2026-10-13
|
#crispr
#dna repair
#nucleosomes
#lesions
#chromatin
|
|
2
|
|
Multiplexed CRISPRi reveals a transcriptional switch between KLF activators and repressors in the maturing neocortex.
(elifesciences.org)
|
Kirk RW
…
Nelson SB
eLife
2026-10-20
|
#transcriptomics
#crispr
#neurogenesis
#transcription
|
|
1
|
|
Quantifying the impact of genetic mutations on enhancer dynamics.
(linkinghub.elsevier.com)
|
Das M
…
Girirajan S
Cell Reports
2026-10-13
|
#enhancer
#transcriptomics
#crispr
#gene regulation
#deep learning
|
|
1
|
|
CRISPR-HAWK: Haplotype- and Variant-Aware Guide Design Toolkit for CRISPR-Cas.
(academic.oup.com)
|
Kumbara A
…
Pinello L
Bioinformatics
2026-10-14
|
#crispr
#genome editing
#genetic variation
#guide-design
#pharmacogenomics
|
|
1
|
|
Structural basis and rational engineering of a thermophilic Cas13a for robust RNA detection.
(linkinghub.elsevier.com)
|
Oladeji SJ
…
Gao Y
Cell Chemical Biology
2026-10-13
|
#crispr
#rna
#diagnostics
#protein design
#structural biology
|
|
1
|
|
Aberrant recursive splicing in a human disease locus.
(linkinghub.elsevier.com)
|
Boone PM
…
Talkowski ME
Cell Reports
2026-10-12
|
#splicing
#adhd
#crispr
#neuropsychiatric
#isoforms
|
|
0
|
|
Structural basis for ITP-selective hydrolysis by a CRISPR-associated Nudix hydrolase.
(journals.asm.org)
|
Wu W
…
Li Z
Journal of Bacteriology
2026-10-12
|
#crispr
#hydrolase
#crystallography
#nucleotide
#toxicity
|
|
0
|
|
Genome editing for hereditary angioedema: A landmark trial and important unanswered questions.
(linkinghub.elsevier.com)
|
Cancian M
…
Margaglione M
Cell Med
2026-10-09
|
#crispr
#gene therapy
#angioedema
#genome editing
#clinical trial
|
|
0
|
|
IGF2BP1 in 17q-gain cooperates with MYCN to regulate purine biosynthesis and immunotherapy efficacy in neuroblastoma.
(pnas.org)
|
Liu J
…
Qing G
PNAS
2026-10-09
|
#neuroblastoma
#immunotherapy
#metabolism
#crispr
#oncology
|