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4
|
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PARP inhibition enhances the antitumor activity of HER3-DXd in non-small cell lung cancer.
(linkinghub.elsevier.com)
|
Lin L
…
Haikala HM
Cell Reports Medicine
2026-08-21
|
#lung cancer
#immunotherapy
#drug combination
#apoptosis
#amr
|
|
2
|
|
Making zombies to kill cancer.
(linkinghub.elsevier.com)
|
Moldoveanu T
Cell Chemical Biology
2026-08-20
|
#senescence
#cancer
#apoptosis
#chemotherapy
#genotoxicity
|
|
0
|
|
Beyond BCL-2: What drives venetoclax resistance in acute myeloid leukemia?
(linkinghub.elsevier.com)
|
Skwarska A
…
Konopleva M
Cancer Cell
2026-08-10
|
#leukemia
#amr
#apoptosis
#metabolism
|
|
0
|
|
Inflammatory kinase TBK1 suppresses homologous recombination DNA repair to sensitize tumors to chemotherapy.
(pnas.org)
|
Zhou W
…
Jiang H
PNAS
2026-08-14
|
#chemotherapy
#dna repair
#cancer
#inflammation
#apoptosis
|
|
0
|
|
ATF4 activates a transcriptional program that chronically suppresses mTOR activity and promotes neurodegeneration in Parkinson disease models.
(linkinghub.elsevier.com)
|
Demmings MD
…
Cregan SP
Cell Reports
2026-08-14
|
#neurodegeneration
#transcriptomics
#apoptosis
#signaling
|
|
0
|
|
RNA terminal uridylyl transferases are druggable vulnerabilities in AML but are dispensable for normal hematopoiesis.
(science.org)
|
Mapperley C
…
Kranc KR
Science Advances
2026-08-12
|
#leukemia
#hematopoiesis
#drug target
#apoptosis
|
|
0
|
|
ONC201 enhances the radiosensitivity of small-cell lung cancer via inhibition of the FAK signaling pathway.
(linkinghub.elsevier.com)
|
Yan Y
…
Chu Q
iScience
2026-08-14
|
#radiosensitivity
#lung cancer
#apoptosis
#signaling
#drug resistance
|
|
0
|
|
Combined FAK and MEK inhibition suppresses chromosome 8 gain malignant peripheral nerve sheath tumors.
(jci.org)
|
Wang G
…
Hirbe AC
Journal of Clinical Investigation
2026-08-11
|
#sarcoma
#aneuploidy
#apoptosis
#kinase inhibitor
#cancer
|
|
0
|
|
The mitochondria enzyme OGDH defends against disulfidptosis by licensing METTL3-regulated NRF2 translation.
(nature.com)
|
Chen XY
…
Chen HZ
Nature Cell Biology
2026-08-07
|
#melanoma
#disulfidptosis
#apoptosis
#metabolism
#oxidative stress
|
|
0
|
|
N-acetylcysteine suppresses retinal defects in Drosophila models of SNRNP200-associated retinitis pigmentosa.
(academic.oup.com)
|
Mayer SK
…
Wallrath LL
Human Molecular Genetics
2026-08-10
|
#retinitis pigmentosa
#photoreceptors
#splicing
#apoptosis
#mitochondria
|
|
0
|
|
Membranolytic peptide programs immunogenic cell death for cancer therapy.
(nature.com)
|
Yuan Y
…
Xiong M
Nature
2026-08-05
|
#immunotherapy
#cancer
#peptide
#immunogenicity
#apoptosis
|
|
0
|
|
Damage recognition by intestinal stem cells via Draper promotes adult Drosophila midgut regeneration.
(link.springer.com)
|
Legido M
…
Patel PH
The EMBO Journal
2026-08-05
|
#regeneration
#stemcells
#apoptosis
#epithelium
#signaling
|
|
0
|
|
BUB1 regulates cell proliferation and apoptosis in cervical cancer by AKT signaling and autophagosome-lysosome fusion via ACTN1.
(linkinghub.elsevier.com)
|
Sun Y
…
Han S
iScience
2026-08-06
|
#cervical cancer
#apoptosis
#autophagy
#signaling
#kinase
|
|
0
|
|
Diabetic and ER-stressed pancreatic islet beta cells are in need of some JNK removal.
(jci.org)
|
Palozzi JM
…
Puigserver P
Journal of Clinical Investigation
2026-08-03
|
#diabetes
#er stress
#apoptosis
#insulin
#signaling
|
|
0
|
|
JNK and p53 cause human and mouse beta cell death during excessive unfolded protein response.
(jci.org)
|
Sharma RB
…
Alonso LC
Journal of Clinical Investigation
2026-08-03
|
#apoptosis
#diabetes
#endoplasmic reticulum stress
#unfolded protein response
#pancreatic-beta-cells
|
|
0
|
|
TRAIL splice variant TRAILshort disrupts T cell receptor signaling and promotes immune tolerance in vivo.
(jci.org)
|
Jalali S
…
Badley AD
Journal of Clinical Investigation
2026-08-03
|
#apoptosis
#immunity
#signaling
#tolerance
|
|
0
|
|
Corisin induces proteostasis stress to drive epithelial injury and pulmonary fibrosis.
(nature.com)
|
Fujimoto H
…
Gabazza EC
Nature Communications
2026-08-01
|
#pulmonary fibrosis
#proteostasis
#microbiota
#apoptosis
#epithelial-injury
|
|
0
|
|
The BAX/BAK apoptotic checkpoint polices entry to therapy-induced senescence.
(linkinghub.elsevier.com)
|
Gallagher Aldave A
…
Martin SJ
Cell Chemical Biology
2026-08-03
|
#apoptosis
#senescence
#chemotherapy
#mitochondrial
#cancer
|
|
0
|
|
Repurposing simeprevir uncovers a druggable KPNB1-p65-BCL2 survival axis in cancer.
(linkinghub.elsevier.com)
|
Li C
…
Sun Q
Cell Chemical Biology
2026-07-31
|
#cancer
#apoptosis
#oncology
#drug-repurposing
#protein localization
|
|
0
|
|
Intermembrane coupling between Bcl-xL and the IP(3) receptor supports local Ca(2+) transfer at ER-mitochondrial contacts.
(linkinghub.elsevier.com)
|
Ghosh A
…
Hajnoczky G
Cell Reports
2026-07-30
|
#calcium
#apoptosis
#mitochondria
#signaling
|