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0
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Single-cell transcriptome analysis reveals onco-fetal reprogramming with implications for drug resistance and clinical outcome.
(genome.cshlp.org)
|
Xu Y
…
Shao T
Genome Research
2026-10-09
|
#transcriptomics
#cancer
#amr
#stemness
#microenvironment
|
|
0
|
|
MAIT cells show promise as an immunotherapy tool with both adaptive and innate characteristics.
(linkinghub.elsevier.com)
|
Sandberg JK
Cell Med
2026-10-09
|
#immunotherapy
#immunity
#cancer
#lymphocyte
|
|
0
|
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Spatially tuned localization of interleukins and OX40 agonists enhances synergistic anti-tumor immunity.
(linkinghub.elsevier.com)
|
Klich JH
…
Appel EA
Cell Reports Medicine
2026-10-09
|
#cancer
#immunotherapy
#cytokine
#drug delivery
#lymphocyte
|
|
0
|
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Hyper-mutational processes provide a head-start for weak cancer drivers: Explaining atypical KRAS variants.
(journals.plos.org)
|
Nicholson MD
…
Tomlinson I
PLOS Computational Biology
2026-10-09
|
#cancer
#mutation
#modeling
#colorectal
#selection
|
|
0
|
|
PI3Kdelta is selectively inhibited by roginolisib by stabilizing the C-terminal helix kalpha12.
(nature.com)
|
Vadas O
…
Hummer G
Nature Communications
2026-10-09
|
#kinase
#inhibitor
#cancer
#crystallography
#selectivity
|
|
0
|
|
Senescent tumor cell membrane-based "time engine" nanosystem amplifies endoplasmic reticulum targeting for metastasis blockade.
(science.org)
|
Tao J
…
Huang Y
Science Advances
2026-10-09
|
#nanotechnology
#drug delivery
#cancer
#senescence
#immunotherapy
|
|
0
|
|
Proteome-guided drug discovery maps and mitigates therapeutic degrader toxicity.
(nature.com)
|
Basu S
…
Ralser M
Nature Chemical Biology
2026-10-09
|
#proteomics
#degraders
#toxicity
#drug discovery
#cancer
|
|
0
|
|
Power-law scaling of mitotic spindles with genome sizes across eukaryotes is driven by chromosome crowding.
(nature.com)
|
Gudlin L
…
Tolic IM
Nature Cell Biology
2026-10-09
|
#genome
#mitosis
#polyploidy
#cancer
#biophysics
|
|
0
|
|
Extracellular matrix-targeted TNC-scFv armoring enhances CAR T cell persistence and antitumor activity in solid tumors.
(science.org)
|
Chen K
…
Ma X
Science Advances
2026-10-09
|
#car-t
#cancer
#immunotherapy
#tumor microenvironment
#transcriptomics
|
|
0
|
|
Punctuated mutagenesis promotes multi-step evolutionary adaptation in human cancers.
(elifesciences.org)
|
Graser CJ
…
Michor F
eLife
2026-10-09
|
#cancer
#evolution
#mutagenesis
#adaptation
#genomics
|
|
0
|
|
SUMO2 deletion changes chromatin accessibility and enhances cytotoxic T cell activation and tumor infiltration.
(science.org)
|
Neranjan Tharuka MD
…
Chen Y
Science Advances
2026-10-09
|
#immunity
#cancer
#immunotherapy
#chromatin
#transcriptomics
|