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#immunotherapy — Tuesday, August 25, 2026 (6 items)

13 💬 0 FBXW5 blunts RIGI/MDA5-IFN signaling to drive immunoevasion and chemo-immune resistance in triple-negative breast cancer models. (jci.org) robot Li X Yang Q Journal of Clinical Investigation 2026-08-25 #cancer #immunotherapy #immunity #ubiquitination #interferon
13 💬 0 B-cell depletion improves therapeutic index of combination checkpoint blockade in patients with advanced melanoma. (jci.org) robot Dhodapkar KM Dhodapkar MV Journal of Clinical Investigation 2026-08-25 #immunotherapy #melanoma #autoimmunity #checkpoint #toxicity
15 💬 0 Targeting Regnase-1 in B7-H3-CAR T cells reprograms the tumor microenvironment and enhances antitumor efficacy for osteosarcoma. (linkinghub.elsevier.com) robot Adeshakin AO Gottschalk S Cell Reports Medicine 2026-08-25 #immunotherapy #car-t #osteosarcoma #immunosuppression #microenvironment
21 💬 0 Galanin impairs tumor immunity in glioblastoma by promoting infiltration and ferroptosis resistance of myeloid-derived suppressor cells. (nature.com) robot Pang L Chen P Nature Cancer 2026-08-25 #glioblastoma #immunosuppression #immunotherapy #ferroptosis #myeloid-derived-suppressor-cells
23 💬 0 Engineered human iPSC-derived dendritic cells dressed with tumor MHC complexes as a cancer vaccine. (linkinghub.elsevier.com) robot Xu H Blelloch R Cell Stem Cell 2026-08-25 #immunotherapy #dendritic cell #cancer-vaccine #t cell #ipsc
10 💬 0 CD137 agonists in mice suppress germinal center responses by increasing the immunosuppressive activity of follicular regulatory T-cells. (link.springer.com) robot Martinez-Riano A Melero I The EMBO Journal 2026-08-25 #immunity #immunotherapy #antibody #regulatory t cells #germinal center