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#immunotherapy — Tuesday, August 25, 2026 (9 items)

0 ℹ B-cell depletion improves therapeutic index of combination checkpoint blockade in patients with advanced melanoma. (jci.org) robot Dhodapkar KM … Dhodapkar MV Journal of Clinical Investigation 2026-08-25 #immunotherapy #melanoma #autoimmunity #checkpoint #toxicity
0 ℹ Galanin impairs tumor immunity in glioblastoma by promoting infiltration and ferroptosis resistance of myeloid-derived suppressor cells. (nature.com) robot Pang L … Chen P Nature Cancer 2026-08-25 #glioblastoma #immunosuppression #immunotherapy #ferroptosis #myeloid-derived-suppressor-cells
0 ℹ CD137 agonists in mice suppress germinal center responses by increasing the immunosuppressive activity of follicular regulatory T-cells. (link.springer.com) robot Martinez-Riano A … Melero I The EMBO Journal 2026-08-25 #immunity #immunotherapy #antibody #regulatory t cells #germinal center
0 ℹ Targeting Regnase-1 in B7-H3-CAR T cells reprograms the tumor microenvironment and enhances antitumor efficacy for osteosarcoma. (linkinghub.elsevier.com) robot Adeshakin AO … Gottschalk S Cell Reports Medicine 2026-08-25 #immunotherapy #car-t #osteosarcoma #immunosuppression #microenvironment
0 ℹ Tumor-derived KLK5 activates TMEM158(+) cancer-associated fibroblasts to induce CD8(+) T cell exhaustion and confer immunotherapy resistance in lung cancer. (linkinghub.elsevier.com) robot Pu S … Gao Y Drug Resistance Updates 2026-08-25 #immunotherapy #lung cancer #fibroblast #immunosuppression #transcriptomics
0 ℹ FBXW5 blunts RIGI/MDA5-IFN signaling to drive immunoevasion and chemo-immune resistance in triple-negative breast cancer models. (jci.org) robot Li X … Yang Q Journal of Clinical Investigation 2026-08-25 #cancer #immunotherapy #immunity #ubiquitination #interferon
0 ℹ Engineered human iPSC-derived dendritic cells dressed with tumor MHC complexes as a cancer vaccine. (linkinghub.elsevier.com) robot Xu H … Blelloch R Cell Stem Cell 2026-08-25 #immunotherapy #dendritic cell #cancer-vaccine #t cell #ipsc
0 ℹ Mutant TP53 hijacks RNA-splicing factor RBM28 to suppress double-stranded RNA triggered antitumor immunity. (nature.com) robot Xiang T … Wu C Nature Communications 2026-08-25 #immunity #cancer #splicing #immunotherapy #interferon
0 ℹ Therapeutic modulation of the vitreoretinal fibrosis microenvironment in female mice using engineered macrophage-derived extracellular vesicles. (nature.com) robot Wang Y … Wei W Nature Communications 2026-08-25 #fibrosis #extracellular vesicles #macrophage #ophthalmology #immunotherapy