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Tuesday, August 04, 2026 (203 items)

0 💬 0 Evolution after whole-genome duplication (WGD) drives phenotypic and transcriptomic divergence more than WGD in an autopolyploid herb. (pnas.org) robot Grunig S Parisod C PNAS 2026-08-04 #polyploidy #transcriptomics #adaptation #evolution #phenotypic
0 💬 0 Markerless gene deletion in Porphyromonas gingivalis using a pheS*-based counterselection system. (journals.asm.org) robot Kim H-M Yu M Microbiology Spectrum 2026-08-04 #mutagenesis #genetic engineering #periodontitis #counterselection
0 💬 0 Thalamo-accumbal circuit adaptations following extended oxycodone abstinence. (elifesciences.org) robot Alonso Caraballo Y Chartoff E eLife 2026-08-04 #opioids #addiction #neuroplasticity #electrophysiology #sex-differences
0 💬 0 Maternal nutrition determines the variable expressivity of STRA6-associated eye malformations. (pnas.org) robot Saadane A von Lintig J PNAS 2026-08-04 #congenital #nutrition #teratology #developmental #ophthalmology
0 💬 0 Deletion of neuroligins from astrocytes does not detectably alter synapse numbers or astrocyte cytoarchitecture by maturity. (elifesciences.org) robot Golf SR Sudhof TC eLife 2026-08-04 #synaptogenesis #astrocyte #neurexins #adhesion #neurobiology
0 💬 0 Desiccation tolerance as a driver of environmental persistence and transmission in nosocomial bacterial pathogens. (journals.asm.org) robot Bucher MJ Green ER Infection and Immunity 2026-08-04 #desiccation #nosocomial #persistence #stress response #virulence
0 💬 0 Establishing the role of ZBTB20 mutations in GnRH deficiency and impaired neurogenesis in the subventricular zone: a human cohort and animal model study. (linkinghub.elsevier.com) robot Guan J Li JD EBioMedicine 2026-08-04 #neurogenesis #hypogonadism #mutation #neurodevelopment #transcriptomics
0 💬 0 Divergent impacts of explainable AI for dermatological diagnosis on clinicians versus lay people. (nature.com) robot Xu X' Ghassemi M Nature Medicine 2026-08-04 #dermatology #explainability #diagnosis #bias #automation
0 💬 0 Transitions between persistent climate-carbon regimes coincide with elevated Phanerozoic biosphere vulnerability. (nature.com) robot Sudakow I Livina V Nature Communications 2026-08-04 #paleoclimate #extinction #biogeochemistry #stability
0 💬 0 Claims of sex-dependent effects in the behavioral and brain sciences are infrequently supported by valid statistical comparisons. (pnas.org) robot Olivier MT Maney DL PNAS 2026-08-04 #statistics #sex-differences #neuroscience #methodology #reproducibility
0 💬 0 Economic preferences predict higher-education choices. (pnas.org) robot Epper TF Zafar B PNAS 2026-08-04 #economics #education #preferences #decision-making
0 💬 0 Pulsatile FXR activation for liver diseases. (linkinghub.elsevier.com) robot Sun P Li W Cell Metabolism 2026-08-04 #pharmacology #hepatology #receptor #metabolism
0 💬 0 Proteasome mutations associated with CANDLE syndrome cause altered neuronal development by dysregulating polyamine synthesis. (jci.org) robot Winkler CW Peterson KE Journal of Clinical Investigation 2026-08-04 #proteasome #neurodegeneration #organoid #polyamines #inborn-errors-metabolism
0 💬 0 Genomic characteristics and geographical distribution of uncultivated soil prokaryotes. (link.springer.com) robot Rodriguez Del Rio A Rillig MC BMC Genomics 2026-08-04 #metagenomics #microbiome #prokaryotes #biogeography #cultivation
0 💬 0 A reference protein atlas of the adult mouse brain vasculature. (pnas.org) robot He L Andaloussi Mae M PNAS 2026-08-04 #proteomics #blood-brain barrier #single-cell #vasculature #neurovascular
0 💬 0 Baicalein suppresses adhesion and biofilm formation in Candida auris. (journals.asm.org) robot Li C Wang C Microbiology Spectrum 2026-08-04 #biofilm #antifungal #transcriptomics #virulence #amr
0 💬 0 Enhancing meningitis diagnosis: a diagnostic stewardship workflow in a resource-limited setting. (journals.asm.org) robot Chiappe Gonzalez A Soria J Microbiology Spectrum 2026-08-04 #meningitis #diagnostics #cns #stewardship #pathogen detection
0 💬 0 Innate immune recognition of Debaryomyces hansenii requires Dectin-1-Card9 signaling. (journals.asm.org) robot Newhall KP Stappenbeck TS Infection and Immunity 2026-08-04 #immunity #yeast #macrophage #inflammation #infection
0 💬 0 Contribution of local Salmonella infection to autoreactivity: divergent roles of type I interferons in colonization and autoantibody production. (journals.asm.org) robot Bessho S Tukel C mBio 2026-08-04 #autoimmunity #biofilm #interferons #infection
0 💬 0 Molecular evaluation of residual disease following neoadjuvant chemotherapy in triple negative breast cancer CALGB40603 (Alliance). (jci.org) robot Radler PD Perou CM Journal of Clinical Investigation 2026-08-04 #transcriptomics #breast cancer #chemotherapy #prognosis #immunity
0 💬 0 Adapting Architecture: Lipid Membrane Remodeling in Mycobacteria. (annualreviews.org) robot Sakarin I Seeliger JC Annual Review of Microbiology 2026-08-04 #mycobacteria #membranes #lipid #antibiotic-resistance #virulence
0 💬 0 Mutation-driven alterations in the AcrB efflux pump modulate antibiotic resistance in Klebsiella pneumoniae. (academic.oup.com) robot Dinata R Mandal SM Journal of Antimicrobial Chemotherapy 2026-08-04 #amr #simulation #protein structure
0 💬 0 Performance of plasma separation cards for HIV drug-resistance genotyping in a resource-limited setting: comparison with plasma samples. (academic.oup.com) robot Pham TH Madec Y Journal of Antimicrobial Chemotherapy 2026-08-04 #genotyping #hiv #amr #sequencing #diagnostics
0 💬 0 eFormate-mediated CO(2) bioconversion: A modular electrochemical-microbial cascade compared across a diverse set of microorganisms. (pnas.org) robot Choi J Simmons BA PNAS 2026-08-04 #electrosynthesis #bioconversion #co2-fixation #metabolic modeling #microbiome
0 💬 0 Leave No Data Behind: Exploring a new paradigm in oncology with foundation models and large language models. (linkinghub.elsevier.com) robot Corso F Prelaj A Cell Reports Medicine 2026-08-04 #oncology #biomarker #machine learning #personalization #diagnosis
0 💬 0 The dystonia-associated Torsin1A sustains CLCC1 function in membrane fusion of the nuclear envelope for NPC biogenesis. (linkinghub.elsevier.com) robot Maslennikova D Kutay U Molecular Cell 2026-08-04 #dystonia #nuclear envelope #membrane fusion #protein-protein interaction
0 💬 0 CD163(+) red pulp macrophages interact with marginal metallophilic macrophages during blood-stage malaria to maintain splenic architecture. (linkinghub.elsevier.com) robot Mauel K Mass E Immunity 2026-08-04 #macrophage #malaria #immunity #transcriptomics #spleen
0 💬 0 Nodal/Smad2 signaling sustains developmental pausing by repressing Pparg-mediated lipid metabolism. (linkinghub.elsevier.com) robot Furlan G Ramalho-Santos M Developmental Cell 2026-08-04 #diapause #signaling #metabolism #embryonic #dormancy
0 💬 0 Human wastewater contamination drives the emergence of multidrug-resistant bacteria in the Galapagos marine ecosystem. (nature.com) robot Lal A Beiting DP Nature Communications 2026-08-04 #amr #metagenomics #wastewater #surveillance #microbiome
0 💬 0 Metabolic crosstalk between c-Myc and glutamine utilization sustains IgM+ B-cell immunity in teleosts. (academic.oup.com) robot Jiao X Wei X Journal of Immunology 2026-08-04 #metabolism #immunity #b-cells #glutamine #activation
0 💬 0 PALM-Scan enables single-molecule site-specific detection of protein S-palmitoylation with a nanopore. (linkinghub.elsevier.com) robot Zhang Z Yang A Molecular Cell 2026-08-04 #nanopore #palmitoylation #ptm #single-molecule #biomarker
0 💬 0 Inter- and intraindividual variability of long-acting injectable cabotegravir/rilpivirine trough concentrations after 1 year of continuous use. (academic.oup.com) robot Sunagawa SW Scarsi KK Journal of Antimicrobial Chemotherapy 2026-08-04 #pharmacokinetics #hiv #variability #therapeutic drug monitoring
0 💬 0 Antigen presentation requirements for effective cDC1-based cancer immunotherapy. (academic.oup.com) robot Pineda JE Gubin MM Journal of Immunology 2026-08-04 #immunotherapy #dendritic cell #cancer #vaccination #antigen-presentation
0 💬 0 Foodborne disease burden in Sweden with a One Health perspective. (linkinghub.elsevier.com) robot Halawa I Guo J iScience 2026-08-04 #foodborne #zoonosis #epidemiology #surveillance #infection
0 💬 0 Methionine tuning for health without frailty. (linkinghub.elsevier.com) robot Garrido A de Cabo R Cell Metabolism 2026-08-04 #nutrition #aging #metabolism #frailty
0 💬 0 Distinct cellular phenotypes of language and executive decline in amyotrophic lateral sclerosis. (linkinghub.elsevier.com) robot Petrescu J Phatnani H Cell 2026-08-04 #transcriptomics #neurodegeneration #glia #cognition
0 💬 0 A CEBPB-IPO4-FASN-MAVS axis limits innate immune activation and viral pneumonia. (linkinghub.elsevier.com) robot Wu J Qi N Cell Reports 2026-08-04 #pneumonia #immunity #transcriptomics #inflammation #covid-19
0 💬 0 Skullcapflavone II alleviates osteoarthritis by inhibiting inflammation and ferroptosis via the SLC7A11/GPX4 signaling pathway. (academic.oup.com) robot Lu J Liu Y Journal of Immunology 2026-08-04 #osteoarthritis #ferroptosis #inflammation #chondrocytes #signaling
0 💬 0 Multi-omics landscapes across the gastritis-to-carcinoma sequence: Stage-specific molecular evolution and microenvironmental remodeling. (linkinghub.elsevier.com) robot Ou J Xu Z iScience 2026-08-04 #transcriptomics #gastric cancer #microbiome #proteomics #spatial omics
0 💬 0 Delivery of extracellular vesicle-associated microRNA-146a regulates human monocyte phenotype and function. (academic.oup.com) robot Mentkowski KI Lang JK Journal of Immunology 2026-08-04 #extracellular vesicles #microrna #monocytes #myocardial-injury #immunity
0 💬 0 Liposomal amphotericin B retrospective multicentre study on mycosis prophylaxis (L-AmB_RUSCO): tolerability and safety of extended-dosing primary antifungal prophylaxis in children with newly diagnosed acute myeloid leukaemia. (academic.oup.com) robot Ricci E Castagnola E Journal of Antimicrobial Chemotherapy 2026-08-04 #antifungal #prophylaxis #leukemia #pediatric #toxicity
0 💬 0 3'UTR-directed, kinase-proximal mRNA decay inhibits C/EBPbeta phosphorylation/activation to suppress senescence in tumor cells. (linkinghub.elsevier.com) robot Salotti J Johnson PF iScience 2026-08-04 #senescence #cancer #mrna decay #transcription #phosphorylation
0 💬 0 Generation and characterization of a novel MHC-II tetramer for tracking and characterization of toxin B-specific CD4+ T cell responses. (academic.oup.com) robot Maslanka JR Abt MC Journal of Immunology 2026-08-04 #immunology #cd4+ t cells #infection #mhc #vaccination
0 💬 0 A fluorogenic biotracer for reliable detection of staphylococcal beta-lactamase: towards improved precision therapy in severe MSSA infections. (academic.oup.com) robot Dupieux C Laurent F Journal of Antimicrobial Chemotherapy 2026-08-04 #amr #diagnostics #staphylococcus #bacteremia
0 💬 0 Factors associated with virological failure in people with HIV treated with bictegravir/emtricitabine/tenofovir alafenamide. Impact of pre-existing mutations and risk of resistance emergence. ANRS-CO3-AquiVIH-NA cohort. (academic.oup.com) robot Bellecave P Bonnet F Journal of Antimicrobial Chemotherapy 2026-08-04 #hiv #amr #genotyping #virological
0 💬 0 CD55 downregulation identifies a pathogenic CD4+ T cell axis linked to p38 MAPK signaling in rheumatoid arthritis. (academic.oup.com) robot Bahabayi A Liu C Journal of Immunology 2026-08-04 #rheumatoid arthritis #t cell #immunity #autoimmunity #transcriptomics
0 💬 0 Effect of glucocorticoid production by the enteric nervous system on neuronal connectivity is blocked during inflammation in a GR-dependent pathway. (linkinghub.elsevier.com) robot Blin J Neunlist M iScience 2026-08-04 #glucocorticoids #enteric #inflammation #neuroplasticity #homeostasis
0 💬 0 Residual yolk depletion matches the establishment of functional oral-intestinal microbiota in hatchling Siamese crocodiles. (linkinghub.elsevier.com) robot Chen JQ Ji X iScience 2026-08-04 #microbiome #16s #colonization #reptile
0 💬 0 Age-related changes in the human T cell receptor alpha repertoire suggest positive selection of dual-specific T cells. (academic.oup.com) robot Nummelin J Arstila TP Journal of Immunology 2026-08-04 #immunology #repertoire #t-cells #sequencing #aging
0 💬 0 PD-L1 restrains T-cell immunity in Nile tilapia by suppressing activation-induced fatty acid synthesis. (academic.oup.com) robot Zhang J Wei X Journal of Immunology 2026-08-04 #immunity #t cell #checkpoint #metabolism #immunosuppression