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Monday, August 03, 2026 (163 items)

0 💬 0 A Bayesian Re-Analysis of the GALFLU Trial of high dose versus standard dose influenza vaccine against hospitalisation outcomes. (academic.oup.com) robot Pardo-Seco J Martinon-Torres F Clinical Infectious Diseases 2026-08-03 #vaccination #influenza #elderly #immunogenicity
0 💬 0 Palmitoylation of TK1 exacerbates osteoarthritis by promoting JNK-mediated metabolic reprogramming. (pnas.org) robot Zhang Z Huang Z PNAS 2026-08-03 #osteoarthritis #proteomics #metabolism #ptm #therapeutics
0 💬 0 Mapping enhancer-gene regulatory interactions from single-cell data. (nature.com) robot Sheth MU Andersson R Nature Genetics 2026-08-03 #enhancer #chromatin #single-cell #epigenomics #gene regulation
0 💬 0 The shape of fitness functions and the distribution of mutational effect sizes jointly limit adaptation by regulatory mutations. (nature.com) robot Aube S Landry CR Nature Ecology & Evolution 2026-08-03 #adaptation #fitness #mutagenesis #regulation #yeast
0 💬 0 Breeding for beneficial microbial associations. (nature.com) robot Rog I van der Heijden MGA Nature Communications 2026-08-03 #microbiome #breeding #agriculture #symbiosis
0 💬 0 The BAX/BAK apoptotic checkpoint polices entry to therapy-induced senescence. (linkinghub.elsevier.com) robot Gallagher Aldave A Martin SJ Cell Chemical Biology 2026-08-03 #apoptosis #senescence #chemotherapy #mitochondrial #cancer
0 💬 0 Sensory processing reallocation from auditory to cardiac signals in REM sleep. (linkinghub.elsevier.com) robot Cataldi J De Lucia M Current Biology 2026-08-03 #interoception #sleep #eeg #evoked-potentials #neuroscience
0 💬 0 Protein neddylation as a therapeutic target: challenges and opportunities. (jci.org) robot Zhang S Sun Y Journal of Clinical Investigation 2026-08-03 #neddylation #ptm #cancer #therapeutics #ubiquitin
0 💬 0 Accurate de novo transcription unit annotation from run-on and sequencing data. (journals.plos.org) robot Munn PR Danko CG PLOS Computational Biology 2026-08-03 #transcriptomics #sequencing #annotation #machine learning
0 💬 0 Bladder mucosal afferents detect UTI and aid pathogen clearance. (pnas.org) robot Tay C Grundy L PNAS 2026-08-03 #uti #neuropathology #innervation #infection #sensation
0 💬 0 Tissue-resident immune cells drive genetic risk in autoimmune and lung diseases. (nature.com) robot Schmiedel BJ Vijayanand P Nature Immunology 2026-08-03 #eqtl #autoimmunity #single-cell #genome-wide association #immunogenetics
0 💬 0 Computational design of antimicrobial peptide nanopores. (nature.com) robot Deb R Vacha R Nature Chemical Biology 2026-08-03 #peptide #amr #computational design #membrane
0 💬 0 A synthetic 3D human cerebrovascular model informed by histology for simulating the cortical depth-dependent BOLD fMRI signal. (journals.plos.org) robot Baez-Yanez MG Petridou N PLOS Computational Biology 2026-08-03 #neuroimaging #hemodynamics #fmri #computational modeling #vasculature
0 💬 0 Identification of novel functional sites in the Ca(v)1.3 calcium channel alpha1-subunit using evolutionary modeling. (pnas.org) robot Tang X Liedl KR PNAS 2026-08-03 #ion channel #computational biology #variant prediction #electrophysiology #neurodevelopmental-disorders
0 💬 0 Haplodiploidy alone does not predict the evolution of eusociality. (linkinghub.elsevier.com) robot Suresh S Linksvayer TA Current Biology 2026-08-03 #eusociality #evolution #haplodiploidy #phylogenetics #insects
0 💬 0 The evolution of genetic drift over 50,000 generations. (academic.oup.com) robot Ascensao JA Hallatschek O Genetics 2026-08-03 #evolution #drift #population-genetics #experimental evolution
0 💬 0 Cell villages and Dirichlet modeling map human cell fitness genetics. (linkinghub.elsevier.com) robot Hanson C Wells MF American Journal of Human Genetics 2026-08-03 #genetics #fitness #screening #proliferation #modeling
0 💬 0 Accurate prediction of gain- and loss-of-function missense variants in GABA(A) receptors. (linkinghub.elsevier.com) robot Bosselmann CM Moller RS EBioMedicine 2026-08-03 #epilepsy #missense #prediction #electrophysiology #channelopathy
0 💬 0 Evolution of botulinum neurotoxin serotype X proteases to induce inflammatory cell death in cancer cells. (nature.com) robot McCreary J Liu DR Nature Biotechnology 2026-08-03 #proteases #cancer #cell death #protein design #immunotherapy
0 💬 0 Bicaudal D acts as a sensor to enable dynein-kinesin co-dependence. (linkinghub.elsevier.com) robot Lu H Trybus KM Current Biology 2026-08-03 #motor-proteins #microtubule #transport #protein-interactions #dynein
0 💬 0 Structure and function of the outer kinetochore. (nature.com) robot Musacchio A Straight AF Nature Reviews Molecular Cell Biology 2026-08-03 #kinetochore #mitosis #chromosome segregation #microtubule #protein complexes
0 💬 0 SIX1 is required for adult cochlear sensory epithelium homeostasis and auditory function. (pnas.org) robot Ma X Xu PX PNAS 2026-08-03 #transcription #hearing #hair cells #epigenomics #gene regulation
0 💬 0 CIP2A-TOPBP1 complex and PP2A dynamically regulate Poltheta recruitment and phosphorylation at mitotic DNA double-strand breaks. (pnas.org) robot Zhao X Zhao G PNAS 2026-08-03 #dna repair #mitosis #phosphorylation #cancer
0 💬 0 Nonantibiotic-driven evolution reveals rare but predictable routes to broad antibiotic resistance. (journals.asm.org) robot Li C Mitchell A mBio 2026-08-03 #amr #evolution #microbiome
0 💬 0 Efficacy of beta-lactam monotherapy versus clindamycin or addition of metronidazole in peritonsillar abscess - an observational cohort study with a focus on Fusobacterium necrophorum. (linkinghub.elsevier.com) robot Loggarfve M Nygren D Clinical Microbiology and Infection 2026-08-03 #infection #antibiotic #microbiology #ent
0 💬 0 Transcription Start Regions in PTU-intergenic regions drive cell cycle-dependent transcriptional activation events in Leishmania donovani. (journals.asm.org) robot Singh A Saha S Microbiology Spectrum 2026-08-03 #transcriptomics #cell cycle #leishmania #gene regulation #polycistronic
0 💬 0 Evolutionary ecology: Islands within islands. (linkinghub.elsevier.com) robot Wan T Current Biology 2026-08-03 #evolution #genetics #conservation #adaptation
0 💬 0 Across species identification of genes bridging neurological and reproductive functions in mammals. (linkinghub.elsevier.com) robot Kizilaslan Z Khatib H iScience 2026-08-03 #transcriptomics #proteomics #comparative genomics #neurology #reproduction
0 💬 0 Diabetic and ER-stressed pancreatic islet beta cells are in need of some JNK removal. (jci.org) robot Palozzi JM Puigserver P Journal of Clinical Investigation 2026-08-03 #diabetes #er stress #apoptosis #insulin #signaling
0 💬 0 Assessing the validity and reliability of computational phenotyping of mood. (journals.plos.org) robot Carrillo P Vinckier F PLOS Computational Biology 2026-08-03 #computational #mood #reliability #phenotyping #validation
0 💬 0 Reticulated adaptive radiation and phylogenomic diversity loss in the Hawaiian honeycreepers. (pnas.org) robot Campana MG Fleischer RC PNAS 2026-08-03 #phylogenomics #adaptive radiation #introgression #extinction #paleogenomics
0 💬 0 Oral lipid prodrug V2043 (1-O-octadecyl-2-O-benzyl-sn-glyceryl-P-remdesivir nucleoside) protects mice from lethal dengue infection. (journals.asm.org) robot Clark AE Carlin AF Antimicrobial Agents and Chemotherapy 2026-08-03 #dengue #antiviral #prodrug #flavivirus #bioavailability
0 💬 0 From Disturbance to Resilience: Early Microbial Community Establishment in Landslide Soils of New Zealand. (academic.oup.com) robot Rasigraf O Wagner D FEMS Microbiology Ecology 2026-08-03 #metagenomics #microbiome #succession #soil #resilience
0 💬 0 Molecular Epidemiology and Drug Resistance of Extraintestinal Pathogenic Escherichia coli Bloodstream Isolates From Adults Worldwide (2011-2023). (academic.oup.com) robot de Been M Weerdenburg E Clinical Infectious Diseases 2026-08-03 #amr #epidemiology #sepsis #bacteremia #sequencing
0 💬 0 Lymphatic therapies open the valve in Marfan syndrome. (jci.org) robot Tian Y Caron KM Journal of Clinical Investigation 2026-08-03 #lymphangiogenesis #valvular-disease #marfan-syndrome #inflammation #cardiovascular
0 💬 0 Mapping the exposome-microbiota-host axis for prenatal origins of infant health. (pnas.org) robot Chen M Xia Y PNAS 2026-08-03 #microbiome #exposome #prenatal #metagenomics #metabolomics
0 💬 0 Good cop, bad cop? Rethinking the roles of cardiac macrophages in injury. (jci.org) robot Karunamurthy J Thanabalasuriar A Journal of Clinical Investigation 2026-08-03 #macrophage #cardiology #inflammation #tissue repair #immunity
0 💬 0 The next generation of antibody-drug conjugates. (nature.com) robot Mosele F Andre F Nature Medicine 2026-08-03 #immunotherapy #oncology #drug delivery #antibody #personalized medicine
0 💬 0 Membrane lipid composition and rapid endocytic retrieval modulate Wingless secretion. (link.springer.com) robot Alvarez-Rodrigo I Vincent JP The EMBO Journal 2026-08-03 #secretion #endocytosis #lipidation #trafficking #signaling
0 💬 0 EGFR inhibition promotes functional engraftment and graft survival via donor-derived CHI3L1 in fetal RPE suspension transplantation. (linkinghub.elsevier.com) robot Mao X Yuan S Cell Reports Medicine 2026-08-03 #transplantation #retinal degeneration #transcriptomics #cell therapy #immunosuppression
0 💬 0 Intratelencephalic neurons in the medial prefrontal cortex mediate the acquisition of goal-directed actions. (linkinghub.elsevier.com) robot Peak JN Balleine BW Cell Reports 2026-08-03 #learning #neuron #plasticity #prefrontal cortex #behavior
0 💬 0 Evolution: Ancient monoamines in a neuron-less animal. (linkinghub.elsevier.com) robot Ferraioli A Burkhardt P Current Biology 2026-08-03 #signaling #evolution #neurobiology #behavior
0 💬 0 Case Commentary: Emergence of clinically relevant fidaxomicin-resistant Clostridioides difficile strains. (journals.asm.org) robot Garey KW Hurdle JG Antimicrobial Agents and Chemotherapy 2026-08-03 #amr #cdi #antibiotic #infection #surveillance
0 💬 0 Norovirus inter-species transmission in an ex vivo model is dependent on virus internalization capacity. (tandfonline.com) robot Villabruna N Gerold G Emerging Microbes & Infections 2026-08-03 #norovirus #zoonosis #gastroenteritis #internalization #transmission
0 💬 0 Structure-Based Insights into the Molecular Mechanisms of LuxR-Type Quorum Sensing Receptors. (annualreviews.org) robot Stoutland IM Blackwell HE Annual Review of Microbiology 2026-08-03 #quorum sensing #structural biology #virulence #signal transduction
0 💬 0 Genetic evolution, phylodynamics, geographic spread of H9N2 avian influenza viruses in China from 2014 to 2025: an increasing potential zoonotic risk. (tandfonline.com) robot Pang Z Sun H Emerging Microbes & Infections 2026-08-03 #influenza #phylodynamics #zoonosis #evolution #sequencing
0 💬 0 Amandine Cornille. (linkinghub.elsevier.com) robot Cornille A Current Biology 2026-08-03 #genomics #evolution #adaptation #biodiversity #domestication
0 💬 0 Evolution on degenerate fitness landscapes is not random: Curvature drives directional drift. (pnas.org) robot Fachareldeen R Brenner N PNAS 2026-08-03 #evolution #fitness #robustness #degeneracy #optimization
0 💬 0 Etiological characterization of acute respiratory tract infections and associated co-infections using Biofire respiratory 2.1 Plus panel. (link.springer.com) robot Kamel NA Elsayed KM BMC Infectious Diseases 2026-08-03 #diagnostics #respiratory #co-infection #virology #molecular
0 💬 0 Diversity and sources of floral microbial communities. (journals.asm.org) robot Khan MQN Ren M-X Applied and Environmental Microbiology 2026-08-03 #microbiome #ecology #pollination #transmission