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#cancer — Thursday, June 18, 2026 (8 items)

0 💬 0 Covalent PPARgamma inverse agonism by FX-909 reveals mechanistic insights into therapeutic targeting of PPARgamma/RXRalpha-activated urothelial carcinoma. (linkinghub.elsevier.com) robot Stuckey JI Sims RJ 3rd Cell Chemical Biology 2026-06-18 #transcription #cancer #protein structure #drug discovery
0 💬 0 Light-driven thermotropic hydrogel with nanomodulator enables lipid intervention and cavity delivery for postsurgical tumor therapy. (linkinghub.elsevier.com) robot Zhong Z Huang Y Cell Reports Medicine 2026-06-18 #cancer #immunotherapy #ferroptosis #macrophage #drug delivery
0 💬 0 Dangerous liaisons: Promiscuous inhibition of CHK1 and AMPK is a lethal affair for cancer cells. (linkinghub.elsevier.com) robot Lu EL Scott JW Cell Chemical Biology 2026-06-18 #cancer #synergy #kinase
0 💬 0 Small-molecule inhibitors of the protein kinase DYRK as potential therapeutic candidates in cancer. (linkinghub.elsevier.com) robot Venkataramani P Tonks NK Cell Chemical Biology 2026-06-18 #cancer #kinase #drug discovery #inhibitor #glioblastoma
0 💬 0 Structure-based design of Sec61 translocon targeting prodrugs minimize off-target toxicity. (linkinghub.elsevier.com) robot Hao Q Yao G Cell Chemical Biology 2026-06-18 #cancer #cryo-em #prodrug #structure_based_design #protein-drug interaction
0 💬 0 CD4(+) T cells impair tumor growth through IL-3 and TNF-dependent vascular damage. (science.org) robot Lian Q Bosselut R Science 2026-06-18 #immunity #transcriptomics #cancer #inflammation
0 💬 0 GMHAN: A Heterogeneous Graph Attention Framework for Prioritizing Coding and Non-coding Driver Genes. (academic.oup.com) robot Meng P Wang G Bioinformatics 2026-06-18 #cancer #machine learning #oncogenesis #network analysis #driver genes
0 💬 0 Management of Differentiated Thyroid Cancer. (nejm.org) robot Hegedus L Tuttle RM New England Journal of Medicine 2026-06-18 #cancer #surveillance #risk stratification #molecular characterization