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#cancer — Monday, June 01, 2026 (38 items)

0 💬 0 Using cancer profiles to identify synthetic lethal therapeutic targets and predictive biomarkers in cancer gene dependency data. (academic.oup.com) robot Pearl LH Pearl FMG Bioinformatics 2026-06-01 #synthetic lethal #crispr #cancer #biomarker #computational
0 💬 0 Emergence of oncofetal plasticity is ubiquitous in early colorectal cancers. (nature.com) robot Buissant des Amorie JR Snippert HJG Nature 2026-06-01 #cancer #microenvironment #metastasis #fibroblast #organoid
0 💬 0 LCR-modules: a collection of workflows for cancer genome analysis. (academic.oup.com) robot Dreval K Morin RD Bioinformatics 2026-06-01 #sequencing #cancer #assembly #transcriptomics
0 💬 0 FourierDrug: a domain generalization framework for robust drug response prediction via frequency-space asymmetric attention. (academic.oup.com) robot Song R Liu H Bioinformatics 2026-06-01 #modeling #drug response #cancer #precision medicine #transcriptomics
0 💬 0 Harnessing the microbiome for cancer therapy. (nature.com) robot Hajjar R Kashyap PC Nature Reviews Microbiology 2026-06-01 #microbiome #cancer #immunity #metabolism #probiotic
0 💬 0 ChromCall: assigning chromatin status to defined genomic regions using epigenomic profiling data. (academic.oup.com) robot Wang B Stead LF Bioinformatics 2026-06-01 #epigenomics #chromatin #cancer
0 💬 0 First-line zolbetuximab plus mFOLFOX6 and nivolumab in unresectable CLDN18.2-positive gastric or gastroesophageal junction adenocarcinoma: a phase 2 trial. (nature.com) robot Shitara K Klempner SJ Nature Medicine 2026-06-01 #cancer #immunotherapy #clinical trial #chemotherapy
0 💬 0 A pro-carcinogenic bacterial toxin binds claudin-4 to cleave E-cadherin. (nature.com) robot White MT Sears CL Nature 2026-06-01 #virulence #microbiome #cancer #inflammation #infection
0 💬 0 Mapping convergent regulators of melanoma drug resistance by PerturbFate. (nature.com) robot Xu Z Cao J Nature 2026-06-01 #transcriptomics #crispr #cancer #single-cell #amr
0 💬 0 Tree reconstruction guarantees from CRISPR-Cas9 lineage tracing data using Neighbor-Joining. (genome.cshlp.org) robot An K Yosef N Genome Research 2026-06-01 #phylogenetics #lineage tracing #crispr #tree reconstruction #cancer
0 💬 0 SLX4IP limits replication stress globally and at ALT telomeres. (link.springer.com) robot Spindler J Panier S The EMBO Journal 2026-06-01 #replication #telomeres #genome stability #cancer #dna repair
0 💬 0 Savolitinib in MET-amplified gastric or gastroesophageal junction adenocarcinoma: a phase 2 trial. (nature.com) robot Peng Z Shen L Nature Medicine 2026-06-01 #cancer #targeted therapy #clinical trial #amplification
0 💬 0 Accurate, scalable and cross-platform cell identification for high-resolution spatial transcriptomics. (nature.com) robot Sun D Wang C Nature Genetics 2026-06-01 #transcriptomics #segmentation #imaging #cancer
0 💬 0 A tumor-on-a-chip for in vitro study of CAR-T cell immunotherapy in solid tumors. (nature.com) robot Liu H Huh DD Nature Biotechnology 2026-06-01 #immunotherapy #modeling #cancer #metabolomics
0 💬 0 The tree labeling polytope: A unified approach to ancestral reconstruction problems. (linkinghub.elsevier.com) robot Schmidt H Raphael BJ Cell Systems 2026-06-01 #phylogenomics #modeling #cancer #inference
0 💬 0 An agentic framework for autonomous scientific discovery in cancer pathology. (nature.com) robot Trost F Tolkach Y Nature Medicine 2026-06-01 #pathology #cancer #prognosis #ai #biomarker
0 💬 0 Caballeronia Bacteremia in Children with Cancer, United States. (wwwnc.cdc.gov) robot Glasgow HL Adderson EE Emerging Infectious Diseases 2026-06-01 #infection #bacteremia #cancer #immunocompromised
0 💬 0 Targeted therapies plus radiotherapy for diffuse intrinsic pontine glioma: the randomized phase 2 BIOMEDE trial. (nature.com) robot Debily MA Grill J Nature Medicine 2026-06-01 #cancer #immunotherapy #sequencing #biomarker
0 💬 0 Age distinguishes selection from causation in cancer genomes. (nature.com) robot Cheek D Naxerova K Nature Genetics 2026-06-01 #cancer #mutation #modeling #selection #aging
0 💬 0 Dynamic transitioning between MAPK-driven and WNT-driven cell states drives intestinal cancer and shapes therapy response. (nature.com) robot Moore AR de Sauvage FJ Nature Genetics 2026-06-01 #cancer #wnt #mapk #stem cell #amr
0 💬 0 Resolving sensitivity, specificity and signal contamination in Xenium spatial transcriptomics. (nature.com) robot Bilous M Gottardo R Nature Methods 2026-06-01 #transcriptomics #cancer #sequencing #segmentation
0 💬 0 SEZ6-targeting antibody-drug conjugate ABBV-706 in advanced small cell lung cancer and solid tumors: a phase 1 trial. (nature.com) robot Byers LA Chandana S Nature Medicine 2026-06-01 #immunotherapy #cancer #clinical trial #drug conjugate #toxicity
0 💬 0 Inflammatory cytokines induce new cancer dependencies. (nature.com) robot Cheruiyot CK Manguso RT Nature Genetics 2026-06-01 #crispr #inflammation #cancer #immunotherapy #metabolism
0 💬 0 Fibroblast growth factor receptor inhibition for succinate dehydrogenase-deficient gastrointestinal stromal tumors: a phase 2 trial. (nature.com) robot Merriam P George S Nature Medicine 2026-06-01 #gist #cancer #targeted therapy #fgfr #sdh
0 💬 0 Gotistobart or docetaxel in metastatic squamous non-small cell lung cancer: stage 1 of the randomized phase 3 PRESERVE-003 trial. (nature.com) robot Cho BC Wu YL Nature Medicine 2026-06-01 #immunotherapy #cancer #clinical trial #lung cancer #ctla-4
0 💬 0 Structures of the neutral amino acid transporter LAT4 provide insights into antitumor effects of its inhibitor tubeimoside-1. (link.springer.com) robot Ding D Yin Y The EMBO Journal 2026-06-01 #cryo-em #cancer #transporter #metabolism #inhibition
0 💬 0 Unraveling lncRNA diversity at a single cell resolution and in a spatial context across different cancer types. (nature.com) robot Prakrithi P Nguyen Q Nature Methods 2026-06-01 #transcriptomics #single-cell #cancer #ncrna
0 💬 0 Structure-guided optimization of SLC1A1/EAAT3-selective inhibitors targeting renal cancer metabolism. (link.springer.com) robot Koochaki P Chakraborty AA The EMBO Journal 2026-06-01 #cancer #metabolism #transporter #inhibitor
0 💬 0 H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs. (nature.com) robot Krug B Lu C Nature Genetics 2026-06-01 #epigenetics #chromatin #differentiation #cancer #pluripotency
0 💬 0 Antibody-bottlebrush prodrug conjugates for targeted cancer therapy. (nature.com) robot Liu B Johnson JA Nature Biotechnology 2026-06-01 #immunotherapy #cancer #drug delivery #conjugate
0 💬 0 Tumor-targeted interferon-alpha gene therapy for glioblastoma: a phase 1 trial. (nature.com) robot Gentner B Naldini L Nature Medicine 2026-06-01 #immunotherapy #glioblastoma #gene therapy #cancer #stem cell
0 💬 0 Trabectedin and low-dose irinotecan to target EWS::FLI1 in Ewing sarcoma: a phase 1/2 trial. (nature.com) robot Grohar PJ Chugh R Nature Medicine 2026-06-01 #ewing sarcoma #transcription factor #chemotherapy #clinical trial #cancer
0 💬 0 Netrin1 blockade alleviates resistance to chemotherapy in pancreatic cancer. (nature.com) robot Roth G Mehlen P Nature 2026-06-01 #amr #cancer #chemotherapy #emt #transcriptomics
0 💬 0 PULPO: pipeline of understanding large-scale patterns of oncogenomic signatures. (academic.oup.com) robot Portasany-Rodriguez M Garcia-Martinez J Bioinformatics 2026-06-01 #structural variation #cancer #mutational signatures #pipeline
0 💬 0 Adherence to Hepatocellular Carcinoma Surveillance Guidelines Among People with HIV and Chronic HBV Infection. (academic.oup.com) robot Berenguer J Rockstroh JK Clinical Infectious Diseases 2026-06-01 #hbv #hiv #cancer #cirrhosis
0 💬 0 StringTie3 improves total RNA-seq assembly by resolving nascent and mature transcripts. (nature.com) robot Shinder I Pertea M Nature Methods 2026-06-01 #transcriptomics #assembly #sequencing #splicing #cancer
0 💬 0 Pathogenic germline variations and cancer risks in pediatric patients referred for genetic testing. (nature.com) robot Wang H Zhou W Nature Medicine 2026-06-01 #sequencing #cancer #germline #pediatric #predisposition
0 💬 0 Recurrent COPA mutation drives R-spondin-independent Wnt activation in intestinal tumors. (nature.com) robot Fujii M Sekine S Nature Genetics 2026-06-01 #organoid #cancer #wnt #mutation #signaling