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#cancer — Wednesday, April 01, 2026 (33 items)

0 💬 0 Homologous recombination deficiency and hemizygosity drive resistance in breast cancer. (nature.com) robot Safonov A Razavi P Nature 2026-04-01 #homologous recombination #cancer #brca2 #mutation #amr
0 💬 0 Ageing promotes metastasis via activation of the integrated stress response. (nature.com) robot Patel AAH Sayin VI Nature 2026-04-01 #metastasis #cancer #metabolism #plasticity #aging
0 💬 0 A clinic-responder-derived defined microbial consortium enhances anti-PD-1 immunotherapy efficacy in mice. (nature.com) robot Zhou H Yang C Nature Microbiology 2026-04-01 #microbiome #immunotherapy #metagenomics #cancer #metabolism
0 💬 0 In vivo site-specific engineering to reprogram T cells. (nature.com) robot Nyberg WA Eyquem J Nature 2026-04-01 #genome editing #immunotherapy #crispr #cancer #gene therapy
0 💬 0 Fecal microbiota transplantation plus pembrolizumab and axitinib in metastatic renal cell carcinoma: the randomized phase 2 TACITO trial. (nature.com) robot Porcari S Ianiro G Nature Medicine 2026-04-01 #microbiome #immunotherapy #cancer #transplantation #dysbiosis
0 💬 0 ZFTA-RELA ependymomas make itaconate to epigenetically drive fusion expression. (nature.com) robot Natarajan SK Venneti S Nature 2026-04-01 #metabolism #epigenetics #cancer #virulence
0 💬 0 Multi-Omics Analysis of Gut Microecological Variations in Colorectal Cancer. (sfamjournals.onlinelibrary.wiley.com) robot Yinhang W Shuwen H Environmental Microbiology 2026-04-01 #microbiome #cancer #metabolomics #sequencing #biomarker
0 💬 0 High-content CRISPR activation screens identify synthetically lethal RNA-based mechanisms to sensitize cancer cells to targeted T cell cytotoxicity. (nature.com) robot Akana RV Jerby L Nature Genetics 2026-04-01 #crispr #immunotherapy #transcriptomics #screening #cancer
0 💬 0 Widespread distribution of Alu/Alu-mediated genomic rearrangement predisposing to a broad range of Mendelian disease and cancer in human populations. (link.springer.com) robot Duan RV Lupski JR Genome Medicine 2026-04-01 #copy_number_variation #mendelian disease #genomic rearrangement #cancer #structural variation
0 💬 0 On the shoulders of a giant: an appraisal of the legacy of Dr. Gerald P Bodey to infectious diseases. (linkinghub.elsevier.com) robot Kontoyiannis DP Chemaly RF Clinical Microbiology and Infection 2026-04-01 #immunocompromised #infection #neutropenia #cancer #amr
0 💬 0 Thymic health and immunotherapy outcomes in patients with cancer. (nature.com) robot Bernatz S Aerts HJWL Nature 2026-04-01 #immunotherapy #biomarker #cancer #immunity #t cell
0 💬 0 Real-world clinical utility of tumor whole-genome sequencing in solid cancers. (nature.com) robot van Putten J Monkhorst K Nature Medicine 2026-04-01 #sequencing #cancer #biomarker #precision medicine
0 💬 0 Dominant clones leverage developmental epigenomic states to drive ependymoma. (nature.com) robot Kardian AS Mack SC Nature 2026-04-01 #epigenomics #cancer #transcriptomics #chromatin
0 💬 0 Identification of non-canonical peptides with moPepGen. (nature.com) robot Zhu C Boutros PC Nature Biotechnology 2026-04-01 #proteogenomics #proteomics #transcriptomics #cancer #modeling
0 💬 0 Harnessing genomics for early cancer detection, risk stratification and prevention. (nature.com) robot Gu M Vassiliou GS Nature Genetics 2026-04-01 #cancer #genomics #screening #methylation #mutation
0 💬 0 GCN5-ERK lactylation-phosphorylation loop amplifies lactate-driven cancer progression. (nature.com) robot Huang B Zhong C Nature Chemical Biology 2026-04-01 #cancer #metabolism #signaling #virulence
0 💬 0 Quemliclustat and chemotherapy with or without zimberelimab in metastatic pancreatic adenocarcinoma: a randomized phase 1 trial. (nature.com) robot Wainberg ZA O'Reilly EM Nature Medicine 2026-04-01 #immunotherapy #cancer #chemotherapy #clinical trial #biomarker
0 💬 0 Global and regional cancer burden attributable to modifiable risk factors to inform prevention. (nature.com) robot Fink H Soerjomataram I Nature Medicine 2026-04-01 #cancer #prevention #epidemiology #risk_factors
0 💬 0 eIF3 musketeers: loyal in health, rogue in disease, and redeemed by therapeutic targeting. (link.springer.com) robot Mohammadinejad R Wolf DA The EMBO Journal 2026-04-01 #translation #therapeutics #cancer #neurodegeneration #infection
0 💬 0 Colonoscopy and fecal immunochemical testing versus usual care in diagnostic colorectal cancer screening: the SCREESCO randomized controlled trial. (nature.com) robot Westerberg M Forsberg A Nature Medicine 2026-04-01 #screening #colonoscopy #cancer #randomized controlled trial
0 💬 0 Selenoprotein P deficiency drives hepatocellular carcinoma progression via induction of neutrophil senescence and immunosuppressive microenvironment. (gut.bmj.com) robot Jiao J Zhan L Gut 2026-04-01 #cancer #immunity #metabolism #senescence #transcriptomics
0 💬 0 Androgen activity in the male embryonic hindbrain drives lethal PFA ependymoma. (nature.com) robot Zhang J Taylor MD Nature 2026-04-01 #ependymoma #androgen #cancer #differentiation
0 💬 0 The integrated stress response promotes immune evasion through lipocalin 2. (nature.com) robot Bossowski JP Papagiannakopoulos T Nature 2026-04-01 #immunotherapy #cancer #immunity #immunosuppression #metabolism
0 💬 0 SLAMF6 as a drug-targetable suppressor of T cell immunity against cancer. (nature.com) robot Li B Veillette A Nature 2026-04-01 #immunotherapy #t cell #cancer #checkpoint #exhaustion
0 💬 0 OR7A10 GPCR engineering boosts CAR-NK therapy against solid tumours. (nature.com) robot Yang L Chen S Nature 2026-04-01 #immunotherapy #engineering #cancer #cytotoxicity #crispr
0 💬 0 Epigenetic memory of colitis promotes tumour growth. (nature.com) robot Nagaraja S Buenrostro JD Nature 2026-04-01 #epigenetics #colitis #cancer #inflammation #transcriptomics
0 💬 0 Time-of-day immunochemotherapy in non-small cell lung cancer: a randomized phase 3 trial. (nature.com) robot Huang Z Zhang Y Nature Medicine 2026-04-01 #immunotherapy #cancer #chronotherapy #clinical trial #chemotherapy
0 💬 0 Fecal microbiota transplantation plus immunotherapy in metastatic renal cell carcinoma: the phase 1 PERFORM trial. (nature.com) robot Fernandes R Maleki Vareki S Nature Medicine 2026-04-01 #microbiome #immunotherapy #cancer #transplantation #immunity
0 💬 0 Risk-adaptive therapy guided by dynamic ctDNA in nasopharyngeal carcinoma. (nature.com) robot Lv J Sun Y Nature 2026-04-01 #ctdna #biomarker #cancer #chemotherapy #prognosis
0 💬 0 AI-based triage and decision support in mammography and digital tomosynthesis for breast cancer screening: a paired, noninferiority trial. (nature.com) robot Elias-Cabot E Alvarez-Benito M Nature Medicine 2026-04-01 #screening #cancer #ai #imaging #automation
0 💬 0 Fecal microbiota transplantation plus immunotherapy in non-small cell lung cancer and melanoma: the phase 2 FMT-LUMINate trial. (nature.com) robot Duttagupta S Elkrief A Nature Medicine 2026-04-01 #microbiome #immunotherapy #metagenomics #cancer #immunity
0 💬 0 Multidimensional profiling of heterogeneity in supratentorial ependymomas. (nature.com) robot Jeong D Filbin MG Nature 2026-04-01 #transcriptomics #cancer #heterogeneity #single-cell
0 💬 0 A small-molecule inverse agonist of PPARgamma for advanced solid tumors: a phase 1 trial. (nature.com) robot Galsky MD Gao X Nature Medicine 2026-04-01 #cancer #drug #clinical trial #toxicity