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#ubiquitination
— top 20, last 14d
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11
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💬 0
FBXW5 blunts RIGI/MDA5-IFN signaling to drive immunoevasion and chemo-immune resistance in triple-negative breast cancer models.
(jci.org)
Li X
…
Yang Q
Journal of Clinical Investigation
2026-08-25
#cancer
#immunotherapy
#immunity
#ubiquitination
#interferon
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9
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💬 0
Cannabinoid tolerance relies on CB(1) receptor ubiquitination by NEDD4L.
(pnas.org)
Alvaro-Blazquez A
…
Guzman M
PNAS
2026-08-25
#ubiquitination
#tolerance
#cannabinoids
#desensitization
#receptor
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4
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💬 0
Autophagy, the Ubiquitin proteasome system, and the MAPK pathway control the temperature dependence of synaptic growth.
(academic.oup.com)
De Leon Gonzalez KM
…
Marie B
Genetics
2026-08-25
#autophagy
#synaptogenesis
#thermobiology
#signaling
#ubiquitination
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2
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💬 0
The degrader gets degraded as cysteine fluctuates.
(linkinghub.elsevier.com)
Chen J
…
Xiao H
Cell Chemical Biology
2026-08-20
#ubiquitination
#proteolysis
#metabolism
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1
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💬 0
USP14 competitively binds to FBXW7 to stabilize MTDH and promotes metastasis and drug resistance of head and neck squamous cell carcinoma.
(pnas.org)
Wang X
…
Liu Y
PNAS
2026-08-19
#cancer
#metastasis
#chemoresistance
#ubiquitination
#signaling
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1
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💬 0
Adipose GGPPS stabilizes BCAT2 to orchestrate BCAA catabolism and lipid mobilization in fasting-induced liver remodeling.
(linkinghub.elsevier.com)
Nie HY
…
Fang L
Cell Reports
2026-08-17
#metabolism
#fasting
#lipid
#adipose
#ubiquitination
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0
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💬 0
FAF1 and FAF2 enhance unfolding by p97-UFD1-NPL4 complex enabling rational design of p97 activators.
(link.springer.com)
Dasgupta P
…
Kulathu Y
The EMBO Journal
2026-08-15
#ubiquitination
#protein design
#proteolysis
#structural biology