|
30
|
|
Eplontersen for Transthyretin Amyloid Cardiomyopathy.
(nejm.org)
|
Fontana M
…
Maurer MS
New England Journal of Medicine
2026-08-28
|
#amyloid
#cardiomyopathy
#oligonucleotide
#clinical trial
#therapeutics
|
|
22
|
|
Induced pluripotent stem cells from discovery to translation.
(nature.com)
|
Lee J
…
Wu JC
Nature Medicine
2026-08-27
|
#stem-cells
#regenerative medicine
#tissue engineering
#genome editing
#therapeutics
|
|
20
|
|
Safety and lipoprotein(a)-lowering effects of Kylo-11, a non-canonical, long-duration small interfering RNA targeting lipoprotein(a): a first-in-human, randomised, double-blind, placebo-controlled, phase 1 trial.
(linkinghub.elsevier.com)
|
Sarraju A
…
Nissen SE
The Lancet
2026-08-28
|
#rnai
#clinical trial
#cardiovascular
#therapeutics
#lipidomics
|
|
12
|
|
Structure-function analysis of the FCRL5-IgG1 Fc complex reveals an unappreciated pathway for B cell modulation by Fc-attenuated IgG.
(science.org)
|
Herpers BM
…
Georgiou G
Science Advances
2026-08-28
|
#immunology
#antibody
#b-cells
#crystallography
#therapeutics
|
|
11
|
|
Microbiome-based therapeutics for Clostridioides difficile infection: additive, subtractive, and modulatory strategies in modern clinical practice.
(tandfonline.com)
|
Cristian RE
…
Chifiriuc MC
Gut Microbes
2026-08-27
|
#microbiome
#cdi
#dysbiosis
#fmt
#therapeutics
|
|
9
|
|
Heritable transgenic schistosomes as a living platform for SARS-CoV-2 neutralizing antibody secretion.
(nature.com)
|
Ittiprasert W
…
Brindley PJ
Nature Communications
2026-08-26
|
#transgenesis
#schistosomiasis
#crispr
#antibody
#therapeutics
|
|
7
|
|
RIBOTAC-mediated degradation of hsa-microRNA-301a-3p suppresses TNBC bone metastasis.
(science.org)
|
Zhou W
…
Luan X
Science Advances
2026-08-26
|
#microrna
#metastasis
#breast cancer
#rna degradation
#therapeutics
|
|
5
|
|
Massively parallel characterization of RNA G-quadruplex stability and molecular recognition.
(academic.oup.com)
|
Martyr JG
…
Dominguez D
Nucleic Acids Research
2026-08-24
|
#g-quadruplex
#rna
#sequencing
#protein-binding
#therapeutics
|
|
4
|
|
Targeting CDKs in the RNAPII transcription cycle.
(nature.com)
|
Fisher RP
…
Geyer M
Nature Reviews Drug Discovery
2026-08-24
|
#transcription
#kinase
#cancer
#therapeutics
#dysregulation
|
|
4
|
|
Neurodegeneration as a dysregulation of neuroimmune crosstalk.
(linkinghub.elsevier.com)
|
Bennett FC
…
Marazzi I
Cell
2026-08-20
|
#neurodegeneration
#neuroimmunology
#inflammation
#immunity
#therapeutics
|
|
3
|
|
Deciphering the comprehensive relationship between 5' UTR and 3' UTR sequences with deep learning.
(academic.oup.com)
|
Suga K
…
Hamada M
Bioinformatics
2026-08-26
|
#deep learning
#rna
#utr
#therapeutics
#translation
|
|
3
|
|
Ferroptosis: significance to zoonotic diseases and therapeutic prospects.
(tandfonline.com)
|
Tian L
…
Wang X
Emerging Microbes & Infections
2026-08-25
|
#ferroptosis
#zoonosis
#immunity
#infection
#therapeutics
|
|
2
|
|
Epigenetic ageing is accelerated in drug-resistant epilepsy and dynamically modulated during ketogenic diet therapy.
(linkinghub.elsevier.com)
|
Gervin K
…
Selmer KK
EBioMedicine
2026-08-22
|
#epigenetics
#epilepsy
#methylation
#aging
#therapeutics
|
|
1
|
|
MAPT splicing modulators reduce 4R tau and rescue tauopathy phenotypes in human neurons and in a mouse model.
(science.org)
|
Silva MC
…
Morini E
Science Translational Medicine
2026-08-19
|
#tauopathy
#splicing
#neurodegeneration
#therapeutics
#frontotemporal-dementia
|
|
1
|
|
Antimicrobial peptides for tuberculosis in a post-antibiotic era: from in vitro promise to therapeutic potential.
(nature.com)
|
Dominic G
…
Oyama LB
npj Antimicrobials and Resistance
2026-08-18
|
#tb
#antimicrobial peptides
#drug resistance
#therapeutics
#mycobacterial
|
|
1
|
|
GLP-1 receptor agonists for Alzheimer's disease: Lessons from trials and translational challenges.
(linkinghub.elsevier.com)
|
Stringhi R
…
Marcello E
Cell Reports Medicine
2026-08-18
|
#neurodegeneration
#neuroprotection
#therapeutics
#clinical-trials
|
|
1
|
|
Engineered HMGB1 construct with tandem Box B domains promotes tissue regeneration without potential for inflammation.
(linkinghub.elsevier.com)
|
Vinals Guitart A
…
Nanchahal J
iScience
2026-08-21
|
#regeneration
#inflammation
#protein design
#immunology
#therapeutics
|
|
1
|
|
Early targeting of the YAP/TEAD-PKC-NF-kappaB axis alleviates post-traumatic osteoarthritis.
(linkinghub.elsevier.com)
|
Ehlen QT
…
Meng Z
iScience
2026-08-21
|
#osteoarthritis
#inflammation
#signaling
#cartilage
#therapeutics
|
|
0
|
|
A serological method's ability to distinguish treatment regimens by assessing early antibody decline in Chagas patients: insights from E1224 data.
(academic.oup.com)
|
Saade U
…
Zrein M
Journal of Infectious Diseases
2026-08-19
|
#chagas
#serology
#parasitology
#therapeutics
#immunoassay
|
|
0
|
|
Lassa fever and Argentine hemorrhagic fever treatment in guinea pigs using broad-spectrum cap-dependent endonuclease inhibitors.
(journals.asm.org)
|
Maruyama J
…
Paessler S
mBio
2026-08-17
|
#hemorrhagic fever
#antiviral
#arenavirus
#drug development
#therapeutics
|