|
30
|
|
A context-dependent framework for targeting NAD metabolism in cancer.
(linkinghub.elsevier.com)
|
Arrizabalaga L
…
Buque A
Cell Metabolism
2026-10-15
|
#metabolism
#cancer
#therapeutics
#signaling
#immunology
|
|
25
|
|
Atomic, structural and molecular insights into GPCR ligand binding and signalling.
(nature.com)
|
Nemec K
…
Babu MM
Nature Reviews Molecular Cell Biology
2026-10-13
|
#receptor
#signalling
#ligand-binding
#therapeutics
|
|
18
|
|
PINK1-mediated mitophagy supports lung cancer initiation and limits the efficacy of KRAS-targeted therapy.
(science.org)
|
Goncalves D
…
Ricci JE
Science Advances
2026-10-16
|
#mitophagy
#lung cancer
#kras
#tumorigenesis
#therapeutics
|
|
14
|
|
Computational design of metalloproteases.
(nature.com)
|
Chen A
…
Baker D
Nature
2026-10-14
|
#proteases
#design
#metalloproteins
#catalysis
#therapeutics
|
|
14
|
|
AI empowers scalable and programmable RNA design.
(linkinghub.elsevier.com)
|
Lin Z
…
Li Y
Molecular Cell
2026-10-15
|
#rna
#synthetic biology
#machine learning
#therapeutics
#design
|
|
12
|
|
Innovative roadmaps for sustainable antimicrobial resistance interventions.
(science.org)
|
Gasperini G
…
De Gregorio E
Science Translational Medicine
2026-10-14
|
#amr
#therapeutics
#diagnostics
#machine learning
#surveillance
|
|
12
|
|
From blunt to precision: Engineering microbiome therapeutics against cancer.
(linkinghub.elsevier.com)
|
Rose AE
…
Zhu W
Cell Host & Microbe
2026-10-14
|
#microbiome
#immunotherapy
#cancer
#therapeutics
|
|
10
|
|
PI3K signaling in breast cancer: therapeutic advances versus adaptive resistance.
(jci.org)
|
Napolitano F
…
Arteaga CL
Journal of Clinical Investigation
2026-10-15
|
#cancer
#signaling
#amr
#therapeutics
#inhibitor
|
|
10
|
|
Next-generation CDK inhibitors in HR+/HER2- breast cancer.
(jci.org)
|
Seriak D
…
Giordano A
Journal of Clinical Investigation
2026-10-15
|
#breast cancer
#cdk-inhibitors
#amr
#cell cycle
#therapeutics
|
|
9
|
|
The impact of modulator therapy on the Pseudomonas aeruginosa cystic fibrosis lung transcriptome.
(pnas.org)
|
Letizia M
…
Whiteley M
PNAS
2026-10-15
|
#transcriptomics
#cystic fibrosis
#infection
#therapeutics
|
|
6
|
|
Combined inhibition of DNA Polymerase Theta and ATR targets MYBL2-high triple-negative breast cancer stem cells.
(jci.org)
|
Bayley R
…
Garcia P
Journal of Clinical Investigation
2026-10-13
|
#breast cancer
#stem cell
#dna repair
#drug resistance
#therapeutics
|
|
3
|
|
Towards broader-spectrum direct-acting antivirals against RNA viruses.
(nature.com)
|
Thibaut HJ
…
Neyts J
Nature Reviews Microbiology
2026-10-07
|
#antiviral
#rna viruses
#drug development
#therapeutics
#broad-spectrum
|
|
2
|
|
HPSC-derived mesenchymal stromal cells ameliorate murine autistic-like phenotypes through activating oxytocinergic neurons.
(science.org)
|
Huang Y
…
Xiang AP
Science Advances
2026-10-09
|
#autism
#oxytocin
#stem-cells
#therapeutics
#neuroinflammation
|
|
2
|
|
Pentosan polysulfate sodium limits pulmonary inflammation in a SARS-CoV-2 mouse model.
(journals.asm.org)
|
Johansen MD
…
Hansbro PM
Microbiology Spectrum
2026-10-13
|
#covid-19
#inflammation
#therapeutics
#immunology
|
|
1
|
|
A second-generation "hypoxia in a pill" rescues neurodegenerative phenotypes across distinct mouse models.
(pnas.org)
|
Wang H
…
Mootha VK
PNAS
2026-10-09
|
#neurodegeneration
#hypoxia
#mitochondrial
#therapeutics
#ataxia
|
|
1
|
|
Nicotinamide Riboside for Patients With Early-Stage Parkinson Disease: The NOPARK Randomized Clinical Trial.
(jamanetwork.com)
|
Brakedal B
…
Tzoulis C
JAMA
2026-10-08
|
#neurodegeneration
#clinical trial
#neuroprotection
#therapeutics
|
|
1
|
|
NA-CDQuant: Quantitative spectral analysis of nucleic acid structure by circular dichroism spectroscopy.
(pnas.org)
|
Mosca K
…
Arluison V
PNAS
2026-10-06
|
#spectroscopy
#nucleic acids
#rna
#therapeutics
|
|
0
|
|
Effect of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID : An Adaptive Randomized Trial.
(acpjournals.org)
|
Reis G
…
Mills EJ
Annals of Internal Medicine
2026-10-06
|
#fatigue
#long covid
#clinical trial
#therapeutics
|
|
0
|
|
Oxazolidinones in the Clinical Management of Staphylococcal Infection-Linezolid or Tedizolid? A review on behalf of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Staphylococci and Staphylococcal Diseases (ESGS).
(academic.oup.com)
|
Macpherson L
…
Goodman AL
Journal of Antimicrobial Chemotherapy
2026-10-06
|
#staphylococcal
#infection
#therapeutics
#pharmacology
#amr
|