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#signaling  — top 20, last 14d

0 💬 0 Desert Hedgehog mediates stem Leydig cell differentiation through Ptch2/Gli1/Sf1 signaling axis. (elifesciences.org) robot Zhao C Wei J eLife 2026-06-29 #spermatogenesis #differentiation #crispr #signaling #androgen
0 💬 0 The mechanism for ligand activation of the Smoothened G protein-coupled receptor. (pnas.org) robot Yu RD Goddard WA 3rd PNAS 2026-06-29 #signaling #gpcr #cancer #protein-binding
0 💬 0 Two-step mechanism of Bruton's tyrosine kinase membrane recruitment and activation. (pnas.org) robot McAllister RA Gupta K PNAS 2026-06-29 #signaling #kinase #membrane #lipid #immunity
0 💬 0 The centrosomal hub unifies regulatory factors of NLRP3 inflammasome activation. (pnas.org) robot Wu M Wu H PNAS 2026-06-30 #inflammasome #immunity #signaling #macrophage
0 💬 0 Epigenetic regulation of mesenchymal BMP signaling directs postnatal organ innervation. (pnas.org) robot Ziaei H Chai Y PNAS 2026-06-30 #epigenetics #innervation #signaling #chromatin
0 💬 0 CPKs are involved in Ca(2+) signaling encoding by enhancing OST1-initiated Ca(2+) influx for ABA-induced stomatal closure in Arabidopsis. (pnas.org) robot Tan YQ Wang YF PNAS 2026-06-30 #signaling #calcium #stomata #kinases #aba
0 💬 0 Combinatorial decision-making driven by multicomponent surface condensates. (pnas.org) robot Zentner A Shrinivas K PNAS 2026-07-01 #condensates #phase separation #signaling #molecular-networks
0 💬 0 The TaMYB55-TaSnRK1alpha1-TabZIP9 module confers heat stress tolerance in wheat. (pnas.org) robot Yang W Xin M PNAS 2026-07-01 #thermotolerance #abiotic-stress #signaling #transcription #crop-improvement
0 💬 0 Nitrogen-TOR targets a bivalent chromatin reader to modulate floral transition. (pnas.org) robot Tian W Zhong X PNAS 2026-07-01 #chromatin #flowering #epigenetics #signaling
0 💬 0 Synthetic essentiality of TRAIL/TNFSF10 in VHL-deficient renal cell carcinoma. (pnas.org) robot Wang X Lu X PNAS 2026-07-01 #cancer #apoptosis #synthetic lethality #signaling #immunotherapy
0 💬 0 Surface immune signaling unlocks NLR activation through mRNA alternative splicing. (science.org) robot Gao C Dong S Science 2026-07-02 #immunity #splicing #amr #signaling #autoimmunity
0 💬 0 Scalable phosphotyrosine enrichment with SH2 superbinder enables deep profiling of EGF responses. (link.springer.com) robot Chang AT Villen J The EMBO Journal 2026-07-03 #phosphoproteomics #signaling #enrichment #proteomics
0 💬 0 Essential role of glycogen synthase kinase 3 in regulating growth, drug response, and infectivity in Leishmania infantum. (journals.asm.org) robot Cruz MGFdML Murta SMF Antimicrobial Agents and Chemotherapy 2026-07-06 #leishmaniasis #amr #signaling #crispr #virulence
0 💬 0 Activity-dependent CO(2) production in the axon triggers opening of Connexin32 in the Schwann cell paranode. (elifesciences.org) robot Butler J Dale N eLife 2026-07-06 #neuropathy #signaling #hemichannels #mitochondria
0 💬 0 Spatial transcriptomic mapping of postnatal mouse uterine development. (pnas.org) robot Jamaluddin MFB Tanwar PS PNAS 2026-07-06 #transcriptomics #epithelium #signaling
0 💬 0 Identification and distribution of a downregulatory signaling alkyloxazole in Streptomyces. (pnas.org) robot Madden M Li J PNAS 2026-07-06 #signaling #secondary metabolism #biosynthesis #antibiotic #genome mining
0 💬 0 Endothelial Arf6 sustains electrical signaling and cerebral blood flow in mice through PIP(2)-dependent activation of Kir2.1 channels. (pnas.org) robot Noterman-Soulinthavong MF Nelson MT PNAS 2026-07-07 #neurovascular #endothelial #electrophysiology #cerebrovascular #signaling
0 💬 0 Intracellular structural modifications of natural peptidoglycan fragments preceding NOD2 signaling in mammalian cells. (pnas.org) robot Feng S Qiao Y PNAS 2026-07-07 #immunity #peptidoglycan #signaling #innate #phosphorylation
0 💬 0 Arabidopsis BSL phosphatases regulate zygote polarity through a brassinosteroid-independent essential function in MAP kinase signaling. (pnas.org) robot Jeong S Lukowitz W PNAS 2026-07-07 #embryogenesis #signaling #phosphatases #kinase #polarity
0 💬 0 PP2A phosphatase regulates Hippo signalling in dual manner. (link.springer.com) robot Sekar A Ribeiro PS The EMBO Journal 2026-07-07 #hippo #phosphatase #signaling #proteostasis