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0
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Functional asymmetry and essential structural roles of PDE6alpha and PDE6beta subunits in rod-photoreceptor integrity.
(pnas.org)
|
Smidak R
…
Palczewski K
PNAS
2026-06-16
|
#photoreceptor
#phosphodiesterase
#vision
#degeneration
#protein structure
|
|
0
|
|
Cryo-EM reveals a right-handed double-helix dimer architecture of PCDH15.
(pnas.org)
|
Liang X
…
Muller U
PNAS
2026-06-16
|
#cryo-em
#mechanotransduction
#protein structure
#hearing
|
|
0
|
|
Structure of the pre-initiation complex explains CMGE biogenesis.
(nature.com)
|
Puhringer T
…
Costa A
Nature
2026-06-17
|
#replication
#cryo-em
#protein structure
#helicase
|
|
0
|
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Covalent PPARgamma inverse agonism by FX-909 reveals mechanistic insights into therapeutic targeting of PPARgamma/RXRalpha-activated urothelial carcinoma.
(linkinghub.elsevier.com)
|
Stuckey JI
…
Sims RJ 3rd
Cell Chemical Biology
2026-06-18
|
#cancer
#drug discovery
#protein structure
#transcription
|
|
0
|
|
Protein-templated synthesis of dinucleotide repeat DNA by an antiphage reverse transcriptase.
(science.org)
|
Deng P
…
Gao A
Science
2026-06-18
|
#reverse transcriptase
#nucleic acid synthesis
#antiphage
#protein structure
|
|
0
|
|
Functional dissection of Corynebacterium glutamicum Wag31 domains for septal recruitment and polar distribution during the cell cycle.
(journals.asm.org)
|
Petit J
…
Wehenkel AM
mBio
2026-06-22
|
#cell-division
#peptidoglycan
#protein structure
#morphogenesis
#diviva
|
|
0
|
|
Structural basis of betaKNL2 centromeric targeting mechanism and its role in plant-specific kinetochore assembly.
(academic.oup.com)
|
Yadala R
…
Lermontova I
Nucleic Acids Research
2026-06-22
|
#kinetochore
#centromere
#chromosome segregation
#protein structure
#plant development
|
|
0
|
|
Spatially resolved profiling of steroid nuclear receptors reveals a role for the disordered N-terminal domains in genome targeting and AP-1 interaction.
(genome.cshlp.org)
|
Zigdon I
…
Barkai N
Genome Research
2026-06-22
|
#transcription
#binding
#genome-targeting
#protein structure
|
|
0
|
|
Structural insights into RNA recognition by the Staphylococcus aureus exoribonuclease YhaM.
(pnas.org)
|
Mattingly JM
…
Dunham CM
PNAS
2026-06-23
|
#exoribonuclease
#virulence
#cryo-em
#rna binding
#protein structure
|
|
0
|
|
Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling.
(elifesciences.org)
|
Zacharia NK
…
Lorentzen E
eLife
2026-06-23
|
#ciliogenesis
#ciliopathy
#ubiquitination
#signaling
#protein structure
|
|
0
|
|
An atlas of microtubule lattice parameters regulated through ligand binding to the microtubule-stabilizing sites.
(pnas.org)
|
Lucena-Agell D
…
Fernando Diaz J
PNAS
2026-06-23
|
#cytoskeleton
#protein structure
#crystallography
#drug binding
|
|
0
|
|
DruGUI 2.0: Mapping Protein Druggability with Probe-Based Molecular Dynamics.
(academic.oup.com)
|
Ventura C
…
Bahar I
Bioinformatics
2026-06-24
|
#druggability
#simulation
#drug discovery
#protein structure
#computational
|
|
0
|
|
Structural insights into spectral tuning and retinal exchange in cone visual pigments.
(science.org)
|
Ohashi S
…
Kandori H
Science
2026-06-25
|
#spectroscopy
#vision
#cryo-em
#protein structure
#photoreception
|
|
0
|
|
PU-GRAIL: residue-level graph learning for identifying protective bacterial antigens under positive-unlabeled supervision.
(academic.oup.com)
|
Jeon J
…
Yeom J
Bioinformatics
2026-07-01
|
#vaccinology
#epitope
#graph-neural-networks
#antigenicity
#protein structure
|
|
0
|
|
Targeted enzyme discovery using metal-coordination mining.
(nature.com)
|
Kipouros I
…
Chang MCY
Nature
2026-07-01
|
#enzyme
#metalloenzyme
#biocatalysis
#protein structure
#halogenase
|
|
0
|
|
3DICE: Interpretable 3D Cross-Modal Learning for Drug-Target Interaction Prediction and Large-Scale Drug Discovery.
(academic.oup.com)
|
Liu AZR
…
Chua MCH
Bioinformatics
2026-07-02
|
#drug discovery
#deep learning
#protein structure
#binding prediction
|
|
0
|
|
Bridging local-global transmembrane protein contexts with contrastive pretraining for alignment-free pathogenicity prediction.
(academic.oup.com)
|
Bao Y
…
Lin GN
Briefings in Bioinformatics
2026-07-03
|
#pathogenicity
#transmembrane
#deep learning
#variant prediction
#protein structure
|
|
0
|
|
Ku70-SAP domain has an overlapping function with DNA-PKcs in limiting the lateral movement of the Ku ring along DNA.
(academic.oup.com)
|
Zhu Y
…
Zha S
Nucleic Acids Research
2026-07-03
|
#dna repair
#nhej
#lymphocyte
#protein structure
|
|
0
|
|
Architecture of the 8 MDa Hdr-Vhu-Fwd super-assembly in class I methanogens.
(nature.com)
|
Paul S
…
Schuller JM
Nature
2026-07-08
|
#methanogenesis
#cryo-em
#methanogens
#electron-bifurcation
#protein structure
|
|
0
|
|
The SepN-FraD structural module serves as an anchor and assembly platform for septal junctions in cyanobacteria.
(linkinghub.elsevier.com)
|
Kieninger AK
…
Weiss GL
Cell Reports
2026-07-09
|
#cyanobacteria
#cryo-em
#intercellular communication
#protein structure
#multicellularity
|