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12
|
|
Targeting CDKs in the RNAPII transcription cycle.
(nature.com)
|
Fisher RP
…
Geyer M
Nature Reviews Drug Discovery
2026-08-24
|
#transcription
#kinase
#cancer
#therapeutics
#dysregulation
|
|
4
|
|
Pervasive phosphorylation by phage T7 kinase disarms bacterial defences.
(nature.com)
|
Bartolec T
…
Savitski MM
Nature
2026-08-19
|
#phage
#phosphorylation
#defence
#kinase
#proteomics
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3
|
|
BRAF and MEK caught in flagrante delicto.
(linkinghub.elsevier.com)
|
Jang DM
…
Eck MJ
Molecular Cell
2026-08-20
|
#phosphorylation
#kinase
#signaling
#crystallography
|
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2
|
|
An Essential Role of the AMPK-Related Kinase Snrk in Regulating Drosophila Sleep.
(academic.oup.com)
|
Yang W
…
Rao Y
Genetics
2026-08-23
|
#sleep
#kinase
#neurotransmission
#cholinergic
|
|
2
|
|
The TaLYK5-TaDSK2a module serves as a molecular switch between plant growth and immunity during fungal attack.
(pnas.org)
|
Wu Y
…
Xu Q
PNAS
2026-08-20
|
#immunity
#signaling
#fungal
#kinase
#pathogen
|
|
2
|
|
Identification of potent inhibitors of JUN N-terminal kinases for treatment of endometriosis and associated pain.
(pnas.org)
|
Madasu C
…
Monsivais D
PNAS
2026-08-19
|
#endometriosis
#inhibitor
#inflammation
#drug discovery
#kinase
|
|
1
|
|
Small-molecule activation of the tumor suppressor kinase LKB1 via the pseudokinase STRAD.
(linkinghub.elsevier.com)
|
Kretschmer LS
…
Gordan JD
Cell Chemical Biology
2026-08-18
|
#kinase
#cancer
#drug design
#allosteric
#tumor suppression
|
|
1
|
|
Emerging roles of ATR beyond DNA damage repair: orchestrating transcriptional reprogramming during epithelial-to-mesenchymal transition.
(jci.org)
|
Mestre-Farrera A
…
Yang J
Journal of Clinical Investigation
2026-08-17
|
#emt
#metastasis
#cancer
#kinase
#transcriptomics
|
|
1
|
|
The structural basis for LRRK2's activation and autoinhibition.
(linkinghub.elsevier.com)
|
Villagran Suarez A
…
Leschziner AE
Cell
2026-08-10
|
#kinase
#neurodegeneration
#gtpase
#cryo-em
#mutation
|
|
0
|
|
RTF2 and CLASPIN localize CHK1 to the replication fork to control S-phase progression.
(science.org)
|
Broton C
…
Smogorzewska A
Science Advances
2026-08-05
|
#checkpoint
#replication
#dna damage
#kinase
|
|
0
|
|
BUB1 regulates cell proliferation and apoptosis in cervical cancer by AKT signaling and autophagosome-lysosome fusion via ACTN1.
(linkinghub.elsevier.com)
|
Sun Y
…
Han S
iScience
2026-08-06
|
#cervical cancer
#apoptosis
#autophagy
#signaling
#kinase
|
|
0
|
|
Structure-conditioned self-supervised learning of residue interaction constraints in protein kinases for variant interpretation.
(academic.oup.com)
|
Fadaei S
…
Zoete V
Bioinformatics
2026-08-01
|
#variant interpretation
#folding
#kinase
#self-supervised learning
#structure prediction
|
|
0
|
|
An AI-enabled structural atlas decodes kinase specificity across the human proteome.
(nature.com)
|
Vanderwall DR
…
Gygi SP
Nature Biotechnology
2026-07-29
|
#phosphorylation
#kinase
#proteomics
#structural prediction
#substrate-specificity
|
|
0
|
|
Brassinosteroid and TPD1 signaling pathways redundantly control anther lobe formation in Arabidopsis thaliana.
(linkinghub.elsevier.com)
|
Chen W
…
Li J
Current Biology
2026-07-30
|
#signaling
#redundancy
#kinase
|