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#inhibitor
— top 20, last 30d
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Identification of potent inhibitors of JUN N-terminal kinases for treatment of endometriosis and associated pain.
(pnas.org)
Madasu C
…
Monsivais D
PNAS
2026-08-19
#endometriosis
#inhibitor
#inflammation
#kinase
#drug discovery
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0
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Bronsted-basic small molecules activate GTP hydrolysis in KRAS-Q61 mutants.
(nature.com)
Wang YC
…
Zhang Z
Nature Chemical Biology
2026-08-12
#oncology
#kras
#inhibitor
#gtpase
#drug discovery
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0
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Sparsomycin inhibits translation through a conserved mechanism across all domains of life.
(academic.oup.com)
Paranjpe MN
…
Polikanov YS
Nucleic Acids Research
2026-08-10
#translation
#ribosome
#crystallography
#inhibitor
#conservation
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0
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BVL3572S inhibits HisC and AlaA, exploiting vitamin B6 dependency to kill Mycobacterium tuberculosis.
(linkinghub.elsevier.com)
Edoo Z
…
Baulard AR
Cell Chemical Biology
2026-08-11
#tb
#antibiotic
#amr
#metabolism
#inhibitor
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0
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Chemical tools for inhibition and activity-based profiling of glucocerebrosidase in vitro and in vivo.
(linkinghub.elsevier.com)
Wang S
…
Phenix CP
Cell Chemical Biology
2026-08-10
#neurodegeneration
#inhibitor
#proteomics
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0
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Development of a structurally distinct TopBP1 inhibitor that enhances PARP blockade and reverses osimertinib resistance.
(science.org)
Lin FT
…
Lin WC
Science Advances
2026-08-05
#cancer
#amr
#inhibitor
#nsclc
#protein-interactions
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Antiviral Effect, Safety, and Tolerability of Oral VH4011499 (VH-499), a New HIV-1 Capsid Inhibitor: Proof-of-Concept Trial.
(academic.oup.com)
Griesel R
…
Benn P
Clinical Infectious Diseases
2026-07-29
#hiv
#pharmacokinetics
#inhibitor
#amr