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#inhibitor
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Small-molecule inhibitors of the protein kinase DYRK as potential therapeutic candidates in cancer.
(linkinghub.elsevier.com)
Venkataramani P
…
Tonks NK
Cell Chemical Biology
2026-06-18
#kinase
#cancer
#inhibitor
#glioblastoma
#drug discovery
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Structural and cellular insights into DCTPP1 antagonists and their synergistic action with DNMT inhibitors.
(pnas.org)
Hauk G
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Berger JM
PNAS
2026-06-23
#cancer
#crystallography
#epigenetics
#drug discovery
#inhibitor
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Development of domain-specific probes of Plasmodium falciparum heat shock protein 70-1.
(journals.asm.org)
Keeler AM
…
Derbyshire ER
Antimicrobial Agents and Chemotherapy
2026-07-02
#malaria
#chaperone
#drug discovery
#inhibitor
#proteomics
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Menin-dependent megakaryocyte proliferation and fibrosis in myeloproliferative neoplasms.
(linkinghub.elsevier.com)
Wen J
…
Crispino JD
Cancer Cell
2026-07-09
#myeloproliferative
#megakaryocyte
#menin
#leukemia
#inhibitor
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Preclinical characterization of HEC116094, an oral inhibitor of the influenza A virus polymerase PB2 subunit.
(tandfonline.com)
Nie L
…
Zhang L
Emerging Microbes & Infections
2026-07-10
#influenza
#antiviral
#preclinical
#inhibitor
#amr
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Molecular imaging-guided discovery of a potent natural FAPalpha inhibitor for liver fibrosis therapy.
(nature.com)
Zhang W
…
Tian J
Nature Communications
2026-07-11
#fibrosis
#imaging
#drug discovery
#inhibitor