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#computational modeling  — top 20, last 30d

0 💬 0 Customizing the structure of minimal TIM barrels to craft efficient de novo enzymes. (nature.com) robot Beck J Hocker B Nature Chemical Biology 2026-06-15 #protein design #computational modeling #catalysis #enzyme design
0 💬 0 Caveat emptor: predicting and modeling protein-DNA recognition and binding via machine-learning computational approaches. (academic.oup.com) robot Esler MA Stoddard BL Nucleic Acids Research 2026-06-22 #protein-dna #machine learning #structural prediction #computational modeling #molecular docking
0 💬 0 Deviance detection via competitive inhibition between local neocortical ensembles. (pnas.org) robot Thorpe RV Jones SR PNAS 2026-06-24 #deviance-detection #neocortex #computational modeling #inhibition #neural circuits
0 💬 0 Analysis of dendritic input currents during place field dynamics. (elifesciences.org) robot Fogel B Ujfalussy BB eLife 2026-07-03 #electrophysiology #dendrites #hippocampus #computational modeling
0 💬 0 Dendritic morphology and synaptic nonlinearities enhance functional complexity in human cortical neurons. (pnas.org) robot Aizenbud I Segev I PNAS 2026-07-07 #neurophysiology #dendrites #synaptic plasticity #computational modeling
0 💬 0 Chaos-generating periodic orbits of topological defects in confined active nematics. (pnas.org) robot Klein B Beller DA PNAS 2026-07-08 #active matter #topological-defects #nematohydrodynamics #fluid dynamics #computational modeling
0 💬 0 Spatially structured heterogeneity shapes large-scale cortical dynamics in a model of the human cortex. (pnas.org) robot Dalla Porta L Sanchez-Vives MV PNAS 2026-07-08 #neurodynamics #cortex #transcriptomics #connectomics #computational modeling
0 💬 0 Rational selection of ketopantoate hydroxymethyltransferase with low product feedback inhibition based on binding free energy calculation analysis. (journals.asm.org) robot Zheng K Zheng Y-G Applied and Environmental Microbiology 2026-07-10 #metabolic modeling #enzyme design #computational modeling #biosynthesis #feedback inhibition