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12
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SPARCS enables scalable recovery of complex image-based phenotypes for genetic screening.
(linkinghub.elsevier.com)
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Schmacke NA
…
Hornung V
Cell
2026-10-06
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#screening
#crispr
#imaging
#proteomics
#autophagy
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10
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Chaperone-mediated autophagy in physiological homeostasis, disease and ageing.
(nature.com)
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Kaushik S
…
Cuervo AM
Nature Reviews Molecular Cell Biology
2026-10-05
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#autophagy
#proteolysis
#aging
#neurodegeneration
#homeostasis
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4
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Disrupting BRD4-BD1-p62 engagement restores protective autophagy.
(linkinghub.elsevier.com)
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Zhang J
…
Ouyang L
Cell Chemical Biology
2026-10-08
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#autophagy
#fibrosis
#pulmonary
#inhibitor
#bromodomain
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3
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|
Nucleocytoplasmic shuttling of USP15 promotes pathological autophagy that disrupts neural stem cell homeostasis and neurodevelopment.
(jci.org)
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Burns KM
…
Yang G
Journal of Clinical Investigation
2026-10-06
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#neurodevelopment
#autophagy
#stemcells
#deubiquitination
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1
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Nitrate-responsive Sialin2 couples stress granule assembly and clearance to maintain neuronal homeostasis.
(linkinghub.elsevier.com)
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Li X
…
Wang S
Developmental Cell
2026-10-02
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#neurodegeneration
#stress-granules
#autophagy
#phase separation
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1
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|
A TBK1/ULK1 signalling axis couples lysosomal stress to TFEB activation.
(nature.com)
|
Esposito A
…
Napolitano G
Nature
2026-09-30
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#autophagy
#lysosomal
#signaling
#lymphoma
#proteostasis
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1
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|
Oncogenic viral infection triggers LAMP2A SUMOylation and chaperone-mediated autophagy to promote tumorigenesis.
(nature.com)
|
Zhang Y
…
Cai Q
Nature Microbiology
2026-09-29
|
#autophagy
#herpesvirus
#oncogenic
#sumoylation
#tumorigenesis
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0
|
|
Atg39-dependent nucleophagy and Atg40-dependent ER-phagy require the Apq12/Brr6/Brl1 complex.
(pnas.org)
|
Liu D
…
Novick P
PNAS
2026-09-30
|
#autophagy
#nucleophagy
#er-phagy
#membrane-remodeling
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0
|
|
ZBED6 deficiency drives pathological cardiac hypertrophy through MEOX1-ERK1/2-dependent autophagy dysfunction.
(journals.plos.org)
|
Zhang X
…
Wu J
PLOS Genetics
2026-10-01
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#cardiomyopathy
#transcriptomics
#autophagy
#signaling
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0
|
|
Excess Met1-linked ubiquitination leads to solid aggregate formation.
(link.springer.com)
|
Kaypee S
…
Ikeda F
The EMBO Journal
2026-09-28
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#ubiquitination
#proteostasis
#aggregation
#autophagy
#immunity
|
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0
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|
Kruppel-like factors regulate lipid homeostasis to modulate SKN-1/Nrf activity, oxidative stress resistance and longevity.
(academic.oup.com)
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Castillo-Quan JI
…
Moroz N
Genetics
2026-09-29
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#oxidative stress
#longevity
#lipid homeostasis
#transcription factor
#autophagy
|
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0
|
|
Cell-intrinsic functions of PD-L1 activate autophagy and prevent cytokine-induced apoptosis.
(science.org)
|
Stefan-Lifshitz M
…
Tomer Y
Science Advances
2026-09-25
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#immunotherapy
#apoptosis
#autophagy
#autoimmunity
#thyroiditis
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0
|
|
Interplay between SFTSV and host innate immunity: Viral evasion mechanisms, pathogenesis, and therapeutic perspectives.
(linkinghub.elsevier.com)
|
Ma X
…
Zhou CM
iScience
2026-09-24
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#immunity
#virology
#autophagy
#evasion
#pathogenesis
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0
|
|
RNA degradation by ribonuclease T2 is required for phosphate homeostasis in S. cerevisiae.
(academic.oup.com)
|
Kee AM
…
Garcia JF
G3: Genes, Genomes, Genetics
2026-09-25
|
#phosphate
#homeostasis
#ribonuclease
#signaling
#autophagy
|
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0
|
|
Autophagy inhibition sensitizes radiotherapy responses in high-grade mutant IDH1 glioma.
(nature.com)
|
Nunez FJ
…
Castro MG
Nature Communications
2026-09-18
|
#autophagy
#glioma
#radiotherapy
#transcriptomics
#epigenetics
|
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0
|
|
High-content image-based screening reveals vaccinia virus membrane proteins as potential regulators of LC3 lipidation.
(journals.asm.org)
|
Krause M
…
Mercer J
Microbiology Spectrum
2026-09-23
|
#autophagy
#vaccinia
#virology
#xenophagy
#screening
|
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0
|
|
Cellular adaptations of fission yeast to inositol starvation.
(journals.asm.org)
|
Sanchez AM
…
Shuman S
mBio
2026-09-21
|
#starvation
#metabolism
#transcriptomics
#yeast
#autophagy
|
|
0
|
|
Cholesterol maintains the degradative capacity of lysosomes during clearance and recycling of dysfunctional mitochondria.
(nature.com)
|
Yang H
…
Saheki Y
Nature Communications
2026-09-16
|
#mitophagy
#lysosomes
#lipid metabolism
#cholesterol
#autophagy
|
|
0
|
|
Quantitative proteomics reveals coordinated changes in the proteome during replicative senescence.
(nature.com)
|
Da Silva Fernandes N
…
Beli P
Nature Communications
2026-09-16
|
#proteomics
#senescence
#proteostasis
#aging
#autophagy
|
|
0
|
|
Quality control of glycogen through direct ubiquitylation by RNF213.
(nature.com)
|
Yip MCJ
…
Randow F
Nature
2026-09-15
|
#autophagy
#ubiquitylation
#glycogen
#neurodegeneration
#proteostasis
|