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0
|
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Phase 2a Randomized Placebo-Controlled Human Challenge Trial of the RSV L-Protein Inhibitor S-337395 for Respiratory Syncytial Virus Infection.
(academic.oup.com)
|
Byrne S
…
Uehara T
Clinical Infectious Diseases
2026-06-15
|
#antiviral
#clinical trial
#rsv
#infection
#virulence
|
|
0
|
|
Consecutive catalytic steps of viral RNA polymerase and exonuclease suggest a way to overcome intrinsic nucleotide analogue resistance.
(pnas.org)
|
Shannon A
…
Canard B
PNAS
2026-06-16
|
#antiviral
#rdrp
#exonuclease
#nucleotide analogues
#coronavirus
|
|
0
|
|
Interferon-induced transmembrane proteins in cancer and virus biology: a membrane perspective.
(journals.asm.org)
|
Xia T
…
Cimarelli A
mBio
2026-06-17
|
#immunity
#antiviral
#cancer
#virulence
|
|
0
|
|
Discovery and characterization of a hydroxypyridone-3-carboxamide analog as an antiviral lead against orthopoxviruses.
(journals.asm.org)
|
Pant A
…
Yang Z
Antimicrobial Agents and Chemotherapy
2026-06-18
|
#antiviral
#drug discovery
#orthopoxviruses
#screening
#pharmacokinetics
|
|
0
|
|
A novel hollow-fiber infection model (HFIM) for antiviral PK/PD studies of CMV infection.
(journals.asm.org)
|
Sudarsono LM
…
Martson A-G
Antimicrobial Agents and Chemotherapy
2026-06-18
|
#pk/pd
#antiviral
#cmv
#modeling
#infection
|
|
0
|
|
Identification of key metabolic enzymes involved in the activation of obeldesivir and remdesivir to the active triphosphate metabolite.
(journals.asm.org)
|
Xu Y
…
Lad L
Antimicrobial Agents and Chemotherapy
2026-06-22
|
#pharmacokinetics
#metabolism
#antiviral
#enzymology
#covid-19
|
|
0
|
|
Imipramine inhibits feline infectious peritonitis virus infection by targeting host cholesterol metabolism via NPC1.
(journals.asm.org)
|
Jing R
…
Liu P
Antimicrobial Agents and Chemotherapy
2026-06-23
|
#antiviral
#infection
#cholesterol
#coronavirus
#inflammation
|
|
0
|
|
The cGAS-STING pathway: Mechanism and medical implications.
(linkinghub.elsevier.com)
|
Hooftman A
…
Ablasser A
Cell
2026-06-25
|
#immunity
#inflammation
#signaling
#antitumor
#antiviral
|
|
0
|
|
Anti-RSV drug screening and inhibition of RSV infection by lapatinib through the IL-17 pathway.
(journals.asm.org)
|
Sun Z
…
Huang S
Antimicrobial Agents and Chemotherapy
2026-06-25
|
#rsv
#antiviral
#cytokine
#drug screening
#immunology
|
|
0
|
|
Favipiravir tissue distribution and inhibitory quotients in preclinical models: towards a pipeline for evidence-based antiviral repurposing.
(academic.oup.com)
|
Petit PR
…
Solas C
Journal of Antimicrobial Chemotherapy
2026-07-02
|
#pharmacokinetics
#antiviral
#drug-distribution
#pharmacodynamics
#repurposing
|
|
0
|
|
Structural insights into the nairovirus nucleoprotein endonuclease activity.
(pnas.org)
|
Li Z
…
Sun L
PNAS
2026-07-07
|
#nairovirus
#nucleoprotein
#endonuclease
#antiviral
#structural
|
|
0
|
|
Lenacapavir-induced lattice hyperstabilization is central to HIV-1 capsid failure at the nuclear pore complex and in the cytoplasm.
(elifesciences.org)
|
Hudait A
…
Voth GA
eLife
2026-07-08
|
#hiv
#capsid
#antiviral
#simulation
|
|
0
|
|
A repair helicase unravels the tangled web of bacterial immunity.
(linkinghub.elsevier.com)
|
Kotovskaya O
…
Isaev A
Cell Host & Microbe
2026-07-08
|
#immunity
#antiviral
#dna repair
#bacterial
#defense
|
|
0
|
|
Virologic insights from the phase 3 REDPINE trial: remdesivir in renally impaired and immunocompromised patients with COVID-19.
(journals.asm.org)
|
Rodriguez L
…
Hedskog C
Antimicrobial Agents and Chemotherapy
2026-07-10
|
#antiviral
#covid-19
#amr
#immunocompromised
#sequencing
|
|
0
|
|
Preclinical characterization of HEC116094, an oral inhibitor of the influenza A virus polymerase PB2 subunit.
(tandfonline.com)
|
Nie L
…
Zhang L
Emerging Microbes & Infections
2026-07-10
|
#influenza
#antiviral
#preclinical
#inhibitor
#amr
|
|
0
|
|
HBsAg seroreversion after pegylated interferon alpha induced HBsAg seroclearance in patients with chronic hepatitis B: a real-world cohort study.
(link.springer.com)
|
Zhang W
…
Song J
BMC Infectious Diseases
2026-07-10
|
#hepatitis
#immunotherapy
#seroreversion
#prognosis
#antiviral
|