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5
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Remibrutinib versus teriflunomide in relapsing multiple sclerosis (REMODEL-1 and REMODEL-2): two randomised, phase 3 trials.
(linkinghub.elsevier.com)
|
Wiendl H
…
Montalban X
The Lancet
2026-10-23
|
#multiple sclerosis
#clinical-trials
#immunotherapy
#relapse
#btk-inhibitors
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1
|
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Dysregulation of the Hippo pathway enhances PD-L2 transcription to promote immune evasion in head and neck squamous cell carcinoma.
(nature.com)
|
Ando T
…
Kajiya M
Communications Biology
2026-10-23
|
#immunotherapy
#carcinoma
#immunity
#signaling
#oncology
|
|
3
|
|
An in situ forming immunomodulatory hydrogel reinvigorates exhausted CD8(+) T cells via preserving their mitochondrial fitness.
(science.org)
|
Qi Y
…
Guo S
Science Advances
2026-10-23
|
#cancer
#immunotherapy
#t-cells
#mitochondria
#immunogenicity
|
|
3
|
|
In situ CAR-M engineered by liposomal mRNA nanomedicine remodels fibrotic microenvironment for ameliorating liver fibrosis.
(science.org)
|
Xiao H
…
Ren J
Science Advances
2026-10-23
|
#rna
#fibrosis
#nanomedicine
#immunotherapy
#macrophage
|
|
7
|
|
Interim Analysis of a Phase 3 Trial of Povetacicept in IgA Nephropathy.
(nejm.org)
|
Barratt J
…
Lafayette R
New England Journal of Medicine
2026-10-23
|
#clinical trial
#immunotherapy
#nephropathy
#autoimmunity
#b-cells
|
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2
|
|
Trastuzumab Rezetecan in ERBB2-Low Advanced Breast Cancer: The HORIZON-Breast06 Randomized Clinical Trial.
(jamanetwork.com)
|
Fan Y
…
Xu B
JAMA
2026-10-23
|
#breast cancer
#clinical trial
#targeted therapy
#immunotherapy
#chemotherapy
|
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7
|
|
Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic cancer: the randomized phase 2 AMPLIFY-7P trial.
(nature.com)
|
George B
…
O'Reilly EM
Nature Medicine
2026-10-23
|
#immunotherapy
#pancreatic cancer
#vaccination
#clinical trial
#immunogenicity
|
|
7
|
|
Determinants of response to CAR T cell therapy in a multicenter, multi-trial cohort analysis of patients with lymphoma.
(nature.com)
|
Budka J
…
Bedognetti D
Nature Medicine
2026-10-23
|
#immunotherapy
#car-t
#lymphoma
#biomarker
#phenotyping
|
|
4
|
|
Extracorporeal photopheresis for the treatment of steroid-refractory immune related adverse events from immune checkpoint inhibitor therapy: a multi-center phase Ib/II clinical trial.
(nature.com)
|
Riemer R
…
Zeiser R
Nature Communications
2026-10-23
|
#immunosuppression
#immunotherapy
#photopheresis
#toxicity
#colitis
|
|
3
|
|
CREBBP loss drives immune evasion by epigenetically silencing STING and MHC-I in small cell lung cancer.
(science.org)
|
Gao Q
…
Jia D
Science Advances
2026-10-23
|
#epigenetics
#immunotherapy
#lung cancer
#immune evasion
#hdac-inhibition
|
|
7
|
|
Bispecific dual T cell agonist invikafusp alfa in solid tumors: the phase 1/2 START-001 trial.
(nature.com)
|
Sullivan RJ
…
Gulley JL
Nature Medicine
2026-10-23
|
#cancer
#clinical trial
#immunotherapy
#antibody
#t cell
|