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#cancer — Friday, October 16, 2026 (10 items)

2 ℹ Chemogenetic ubiquitin E1 inhibitor TAK-243 CRISPR screen uncovers HAPSTR1/HUWE1 axis in chromatin proteostasis and cell cycle control. (science.org) robot van Overbeek NK … Vertegaal ACO Science Advances 2026-10-16 #crispr #ubiquitination #proteostasis #cell cycle #cancer
2 ℹ Targeting MMGT1 enhances immunotherapy efficacy in triple-negative breast cancer. (linkinghub.elsevier.com) robot Liu S … Xu M Cell Reports Medicine 2026-10-16 #cancer #immunotherapy #immunity #senescence #metabolism
4 ℹ AmpliconSuite: an end-to-end workflow for analyzing focal amplifications in cancer genomes. (nature.com) robot Luebeck J … Bafna V Nature Methods 2026-10-16 #cancer #amplification #sequencing #oncogene #extrachromosomal
2 ℹ NKG2D overexpression potentiates CAR-T cells through costimulation by tumor NKG2D ligands. (linkinghub.elsevier.com) robot Li J … Han W Cell Reports Medicine 2026-10-16 #immunotherapy #car-t #cancer #activation #exhaustion
1 ℹ Lipid-based mRNA chimeric antigen receptor T cells for enhanced in vitro antitumor activity. (linkinghub.elsevier.com) robot Gao H … Qian Q iScience 2026-10-16 #immunotherapy #rna #lipid nanoparticles #cancer #transfection
1 ℹ BUB signaling in cancer and molecular insights into targeted therapies. (nature.com) robot Baweja B … Nema R Communications Biology 2026-10-16 #cancer #cell cycle #targeted therapy #chromosomal instability #biomarker
2 ℹ Programmable and selective silencing of oncogenic fusion transcripts by CRISPR-Cas13b via breakpoint sequence recognition. (science.org) robot Hu 胡文欣 W … Fareh M Science Advances 2026-10-16 #crispr #fusion #cancer #leukemia #transcriptomics
2 ℹ Therapeutic-scale CAR-NK microrobots with programmable swarm navigation for targeted solid tumor therapy. (science.org) robot Wu Z … Zhao J Science Advances 2026-10-16 #cancer #immunotherapy #nanoparticles #microrobots #engineering
1 ℹ IPO5 contributes to cetuximab resistance in colorectal cancer by modulating Ras signaling. (linkinghub.elsevier.com) robot Yuan Q … Li X iScience 2026-10-16 #amr #cancer #cetuximab #signaling #apoptosis
6 ℹ One structural class, one treatment? Firmonertinib in PACC-mutant NSCLC. (linkinghub.elsevier.com) robot Huang DD … Yang JC Cancer Cell 2026-10-16 #cancer #nsclc #tyrosine kinase inhibitor #targeted therapy