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0
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Preclinical and first-in-human evaluation of VG-3927/SAR448851, an oral small-molecule TREM2 agonist for Alzheimer's disease.
(science.org)
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Dejanovic B
…
Mirescu C
Science Translational Medicine
2026-10-14
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#neurodegeneration
#microglia
#immunotherapy
#neuroinflammation
#drug development
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0
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Engineered TYK2 dependence enables myeloid-selective IL-10 receptor agonism.
(nature.com)
|
Canaria DA
…
Yi T
Nature
2026-10-14
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#inflammation
#immunotherapy
#cytokine
#myeloid
#signaling
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0
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Restoration of PP2A AalphaB56alphaC trimer formation by RPT04402 molecular glue in high-grade uterine cancer.
(science.org)
|
Peris I
…
Narla G
Science Translational Medicine
2026-10-14
|
#oncology
#mutation
#phosphatase
#proteomics
#immunotherapy
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0
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Personalized neoantigen-targeting cancer vaccines in ovarian cancer: a phase 1 trial.
(nature.com)
|
Sellars MC
…
Wu CJ
Nature Medicine
2026-10-14
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#vaccination
#immunotherapy
#ovarian cancer
#personalized medicine
#neoantigen
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0
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Macrophage- or neutrophil-expressed UPP1 drives tumor growth and immune suppression in the tumor microenvironment.
(science.org)
|
Li Y
…
Lu C
Science Advances
2026-10-14
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#immunosuppression
#immunotherapy
#tumor microenvironment
#transcriptomics
#macrophage
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0
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CAR T cells from code to clinic: Framing modeling approaches with current translational research goals.
(linkinghub.elsevier.com)
|
Sant'Anna LE
…
Mayalu MN
Cell Systems
2026-10-14
|
#modeling
#immunotherapy
#cell therapy
#cancer
#translational
|
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0
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|
From blunt to precision: Engineering microbiome therapeutics against cancer.
(linkinghub.elsevier.com)
|
Rose AE
…
Zhu W
Cell Host & Microbe
2026-10-14
|
#microbiome
#immunotherapy
#cancer
#therapeutics
|
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0
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|
Selective inhibition of IL-6 trans-signalling reveals distinct mechanisms of human classic and trans-signalling receptor-complex formation.
(nature.com)
|
Rieneck E
…
Dittrich A
Communications Biology
2026-10-14
|
#inflammation
#cytokine
#antibody
#signaling
#immunotherapy
|
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0
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|
Orthogonal Fc engineering enables multiplexed delivery of mRNA-encoded bispecific antibodies that constrain viral escape.
(science.org)
|
Wec AZ
…
Walker LM
Science Translational Medicine
2026-10-14
|
#covid-19
#antibody
#rna
#viral escape
#immunotherapy
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0
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|
Immune biomarkers of response and resistance to ipilimumab and nivolumab in metastatic castration-resistant prostate cancer.
(science.org)
|
Tsimberidou AM
…
Sharma P
Science Advances
2026-10-14
|
#immunotherapy
#biomarker
#prostate cancer
#checkpoint-inhibitors
#immunogenomics
|
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0
|
|
Compartment-specific PPARdelta activity controls the outcome of cancer-immune cell competition and immunotherapy efficacy.
(nature.com)
|
Bunk P
…
Beyaz S
Nature Immunology
2026-10-14
|
#cancer
#immunotherapy
#immunity
#t-cells
#metabolism
|
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0
|
|
Tumor DNA methylation subtypes and expression levels of CFISH predict response and overall survival to immunochemotherapy.
(linkinghub.elsevier.com)
|
Fuchs HS
…
Lu X
Cell Med
2026-10-14
|
#methylation
#immunotherapy
#transcriptomics
#biomarker
#esophageal cancer
|
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0
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|
A protective hybrid protein vaccine informed by mapping major histocompatibility class II epitopes in Cryptococcus neoformans chitin deacetylases that stimulate CD4(+) T-cell responses.
(journals.asm.org)
|
Specht CA
…
Levitz SM
mBio
2026-10-14
|
#vaccination
#immunology
#cryptococcosis
#epitope
#immunotherapy
|
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0
|
|
ATG16L2 as a prognostic biomarker and therapeutic target in kidney renal clear cell carcinoma.
(linkinghub.elsevier.com)
|
Xu X
…
Wang Q
iScience
2026-10-14
|
#autophagy
#carcinoma
#immunotherapy
#biomarker
#prognosis
|