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0
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Mitochondrial NADP(H)-dependent de novo dTMP biosynthesis counteracts the cytotoxicity of PARP inhibitors.
(pnas.org)
|
Li Q
…
You H
PNAS
2026-09-24
|
#mitochondrial
#metabolism
#cancer
#amr
#dna repair
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0
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Altered physiology of drug-resistant Mycobacterium tuberculosis restricts adaptation to host-relevant conditions and produces condition-dependent collateral vulnerabilities.
(journals.asm.org)
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Jowsey WJ
…
McNeil MB
mBio
2026-09-24
|
#tb
#amr
#metabolism
#metabolomics
#fitness-cost
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0
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Ceramide synthesis mediates colorectal cancer metastasis through a YAP-driven regenerative program.
(science.org)
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Goswami S
…
Yilmaz OH
Science
2026-09-24
|
#metastasis
#colorectal cancer
#ceramide
#metabolism
#signaling
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0
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MCUB restricts mitochondrial calcium to support metabolic adaptation and homeostasis in glioblastoma.
(linkinghub.elsevier.com)
|
Sun N
…
Jiang C
Cell Reports
2026-09-24
|
#glioblastoma
#metabolism
#mitochondria
#radiotherapy
#homeostasis
|
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0
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How mitochondrial heterogeneity fuels a dynamic organelle ecosystem.
(nature.com)
|
Desmaison PJ
…
Bertolin G
Communications Biology
2026-09-24
|
#mitochondria
#heterogeneity
#metabolism
#organelles
#bioenergetics
|
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0
|
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Mammals produce cyclo-octasulfur to suppress lipid peroxidation and ferroptosis.
(science.org)
|
Barayeu U
…
Akaike T
Science
2026-09-24
|
#ferroptosis
#lipid peroxidation
#metabolism
#oxidative stress
#osteoarthritis
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0
|
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Inverse directions of association of higher physical activity and higher insulin resistance with human skeletal muscle fiber-type gene expression.
(linkinghub.elsevier.com)
|
Ciotlos DL
…
Scott LJ
iScience
2026-09-24
|
#transcriptomics
#muscle
#metabolism
#insulin resistance
#chromatin
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0
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The Gibbs free energy landscape based on liver metabolome revealed thermodynamic robustness against fasting and obesity.
(linkinghub.elsevier.com)
|
Abekawa T
…
Kuroda S
iScience
2026-09-24
|
#metabolomics
#thermodynamics
#metabolism
#fasting
#obesity
|
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0
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FluxAtlas is a pan-cancer metabolic flux atlas that identifies tumor-selective dependencies and prognostic biomarkers.
(linkinghub.elsevier.com)
|
Kohli M
…
Poulogiannis G
Cell Reports
2026-09-24
|
#metabolomics
#metabolism
#cancer
#modeling
#biomarker
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