#autoimmunity — Friday, September 18, 2026 (4 items)
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mRNA-encoding CD19-targeting T cell engager for refractory immune thrombocytopenia.
(linkinghub.elsevier.com)
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Cell 2026-09-18 | #immunotherapy #rna #autoimmunity #thrombocytopenia #car-t | |
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CTLA-4 haploinsufficiency leads to late-onset autoimmune pathology in mice.
(linkinghub.elsevier.com)
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iScience 2026-09-18 | #autoimmunity #immunodeficiency #ctla-4 #regulatory t cells #haploinsufficiency | |
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DGKalpha and zeta deficiency causes regulatory T-cell dysregulation, destabilization, and conversion to pathogenic T-follicular helper cells to trigger IgG1-predominant autoimmunity.
(elifesciences.org)
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eLife 2026-09-18 | #autoimmunity #immunoregulation #tolerance #lymphocyte #differentiation | |
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Super-enhancer-driven SGK1 activates polyamine metabolism to promote autoimmune uveitis.
(doi.org)
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Science Advances 2026-09-18 | #autoimmunity #uveitis #transcriptomics #immunometabolism #t-cells |