#innate immunity — Friday, September 11, 2026 (2 items)
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A highly prevalent lupus risk haplotype increases IRF7-dependent induction of IFN-alpha, enhancing antiviral defense and exacerbating autoimmunity.
(linkinghub.elsevier.com)
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American Journal of Human Genetics 2026-09-11 | #autoimmunity #interferon #lupus #genetics #innate immunity | |
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Direct activation of SARM1 by dsDNA is not supported by biochemical and cellular evidence.
(pnas.org)
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PNAS 2026-09-11 | #axodegeneration #biochemistry #nad metabolism #innate immunity #protein activation |