A highly prevalent lupus risk haplotype increases IRF7-dependent induction of IFN-alpha, enhancing antiviral defense and exacerbating autoimmunity. (linkinghub.elsevier.com)

Authors: Virolainen SJ … Kottyan LC Journal: American Journal of Human Genetics Published: 2026-09-11 DOI: https://doi.org/10.1016/j.ajhg.2026.08.016