#synthetic lethality — Tuesday, September 01, 2026 (3 items)
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GiGCN: a network-based framework for uncovering synthetic lethal and viable genetic interactions.
(academic.oup.com)
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Briefings in Bioinformatics 2026-09-01 | #synthetic lethality #genetic interactions #network analysis #computational biology #machine learning | |
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The Fanconi anemia pathway restrains MLL-rearranged leukemogenesis through suppressing non-homologous end joining-mediated genomic instability.
(nature.com)
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Nature Communications 2026-09-01 | #leukemia #dna repair #genomic instability #synthetic lethality #oncology | |
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Explainable/interpretable artificial intelligence and knowledge graph neural network for synthetic lethality prediction: overview, challenges, and future directions.
(academic.oup.com)
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Briefings in Bioinformatics 2026-09-01 | #synthetic lethality #cancer #machine learning #multi-omics #drug discovery |