#splicing — Wednesday, August 19, 2026 (2 items)
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Long-read proteogenomic atlas of human neuronal differentiation reveals isoform diversity informing neurodevelopmental risk mechanisms.
(nature.com)
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Nature Communications 2026-08-19 | #transcriptomics #splicing #neurodevelopment #proteogenomics #autism | |
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MAPT splicing modulators reduce 4R tau and rescue tauopathy phenotypes in human neurons and in a mouse model.
(science.org)
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Science Translational Medicine 2026-08-19 | #splicing #tauopathy #therapeutics #neurodegeneration #frontotemporal-dementia |