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#frontotemporal-dementia  — top 20, last 7d

20 💬 0 Carboxyl-terminal blockade of sortilin binding enhances progranulin gene therapy in a mouse model of frontotemporal dementia. (science.org) robot Kashyap SN Roberson ED Science Translational Medicine 2026-08-19 #neurodegeneration #gene therapy #frontotemporal-dementia #neuroinflammation #protein design
20 💬 0 MAPT splicing modulators reduce 4R tau and rescue tauopathy phenotypes in human neurons and in a mouse model. (science.org) robot Silva MC Morini E Science Translational Medicine 2026-08-19 #splicing #tauopathy #therapeutics #neurodegeneration #frontotemporal-dementia