#frontotemporal-dementia — Wednesday, August 19, 2026 (2 items)
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Carboxyl-terminal blockade of sortilin binding enhances progranulin gene therapy in a mouse model of frontotemporal dementia.
(science.org)
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Science Translational Medicine 2026-08-19 | #neurodegeneration #gene therapy #frontotemporal-dementia #neuroinflammation #protein design | |
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MAPT splicing modulators reduce 4R tau and rescue tauopathy phenotypes in human neurons and in a mouse model.
(science.org)
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Science Translational Medicine 2026-08-19 | #splicing #tauopathy #therapeutics #neurodegeneration #frontotemporal-dementia |