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0
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TIGRa: An ultra-compact programmable activator enabling multiplexed and efficient gene regulation.
(linkinghub.elsevier.com)
|
Liu Z
…
Sun Y
Cell Stem Cell
2026-08-10
|
#activation
#crispr
#gene therapy
#synthetic biology
#transcriptional-regulation
|
|
0
|
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Specific cleavage of 5' overhangs of non-target strand by Cas9 activated by target DNA binding.
(academic.oup.com)
|
Lv S
…
Zheng L
Nucleic Acids Research
2026-08-10
|
#crispr
#genome editing
#off-target
#diagnostics
|
|
0
|
|
A CRISPR/Cas9-induced blunt-end telomere system in S. pombe reveals RNase H2-dependent RNA primer removal at the terminal Okazaki fragment of lagging telomeres.
(academic.oup.com)
|
Zou S
…
Zhou JQ
Nucleic Acids Research
2026-08-10
|
#telomeres
#crispr
#replication
#rnase
|
|
0
|
|
Zebrafish knockout models of atxn1a, atxn1b, and atxn1l reveal distinct and shared phenotypic and transcriptomic alterations.
(academic.oup.com)
|
Karim A
…
Orengo JP
Human Molecular Genetics
2026-08-10
|
#transcriptomics
#neurodegeneration
#crispr
#ataxia
#behavioral
|
|
0
|
|
CRISPR RNA architecture steers Cas9 catalysis and fidelity via a guide repeat clasp motif.
(academic.oup.com)
|
Chilamkurthy R
…
Gagnon KT
Nucleic Acids Research
2026-08-10
|
#crispr
#genome editing
#specificity
#rna structure
#structural biology
|
|
0
|
|
Plasticity-first evolution via CYP405 loss shaped chemical defences in butterflies.
(academic.oup.com)
|
Pinheiro de Castro EC
…
Jiggins CD
Molecular Biology and Evolution
2026-08-10
|
#evolution
#plasticity
#biosynthesis
#defense
#crispr
|
|
0
|
|
Nuclear compartmentalization at the G1/S transition plays a key role in DNA replication control.
(nature.com)
|
Oji A
…
Hiratani I
Nature Communications
2026-08-10
|
#chromatin
#replication
#cell cycle
#crispr
|
|
0
|
|
CRISPR/dCas9-mediated tuning of DMPK transcription reveals a quantitative relationship between toxic repeat RNA expression and MBNL1 activity in myotonic dystrophy.
(academic.oup.com)
|
Ripken L
…
Wansink DG
Human Molecular Genetics
2026-08-10
|
#crispr
#myotonic dystrophy
#splicing
#repeat expansion
#transcriptional-regulation
|