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Thursday, July 23, 2026 (73 items)

0 💬 0 HUWE1 targets mitochondria via RMC1 to promote neurodevelopment. (pnas.org) robot Yi J Jia D PNAS 2026-07-23 #neurodevelopment #ubiquitination #mitochondria #intellectual disability #proteostasis
0 💬 0 Measurement accuracy in mechanobiology: A unifying statistical framework for testing cellular forces. (pnas.org) robot Boquet-Pujadas A PNAS 2026-07-23 #mechanobiology #microscopy #biophysics #statistical #imaging
0 💬 0 Contributions of persisters and the Eagle effect to survival of Yersinia pseudotuberculosis under clinical antimicrobials. (journals.asm.org) robot Goode O Pagliara S Microbiology Spectrum 2026-07-23 #amr #persisters #tolerance #yersinia #pathogenesis
0 💬 0 Dose-dependent sensitivity of human three-dimensional chromatin to a heart disease-linked transcription factor. (science.org) robot Grant ZL Bruneau BG Science 2026-07-23 #chromatin #transcription #cardiomyocyte #congenital-heart-disease #differentiation
0 💬 0 Enfortumab Vedotin and Pembrolizumab in Cisplatin-Eligible Bladder Cancer. (nejm.org) robot Galsky MD Gomez de Liano A New England Journal of Medicine 2026-07-23 #immunotherapy #bladder cancer #clinical trial #neoadjuvant #chemotherapy
0 💬 0 An activity-resistance trade-off constrains enzyme evolution. (pnas.org) robot Sarkis AW Hedstrom L PNAS 2026-07-23 #evolution #amr #enzyme #horizontal transfer #antibiotic
0 💬 0 The population structure of invasive Lantana camara is shaped by its mating system. (elifesciences.org) robot Praveen P Ramakrishnan U eLife 2026-07-23 #genetics #invasive species #snp #mating-system #inbreeding
0 💬 0 The rise and fall of language diversity through the Holocene. (science.org) robot Blasi DE Bowern CL Science 2026-07-23 #linguistics #historical #population #computational
0 💬 0 Antiretroviral Therapy. (nejm.org) robot Gulick RM New England Journal of Medicine 2026-07-23 #hiv #pharmacotherapy #virology #amr
0 💬 0 A tiny cone of reactivity. (science.org) robot Bjork J Science 2026-07-23 #reactivity #molecular #kinetics
0 💬 0 The multilayered cuticle underlying structural coloration in red algae shares features with the metazoan extracellular matrix. (pnas.org) robot Philippe G Collen J PNAS 2026-07-23 #proteomics #transcriptomics #extracellular matrix #algae #metabolomics
0 💬 0 Safe Sleep Video Intervention via Text Messaging to Low-Income Families: The SMARTER Randomized Clinical Trial. (jamanetwork.com) robot Moon RY Corwin MJ JAMA 2026-07-23 #intervention #randomized-trial #maternal health #prevention #infant-mortality
0 💬 0 High-coverage ancient genomes reveal divergent population histories and prehistoric starch-related genetic variation in Japan. (pnas.org) robot Ishiya K Ueda S PNAS 2026-07-23 #paleogenomics #genetics #migration #demographic inference
0 💬 0 Structural dynamics of IRE1 and its interaction with unfolded peptides. (elifesciences.org) robot Spinetti E Covino R eLife 2026-07-23 #folding #stress response #simulation #structural biology
0 💬 0 Human body single-cell atlas of three-dimensional genome organization and DNA methylation. (science.org) robot Zhou J Ecker JR Science 2026-07-23 #epigenomics #chromatin #methylation #single-cell #atlas
0 💬 0 Step geometry-guided growth of rhombohedral graphene. (science.org) robot Zhao M Liu K Science 2026-07-23 #graphene #synthesis #epitaxy #topology
0 💬 0 Decoding 3D chromatin architecture reveals distinct enhancer classes underlying hierarchical gene regulation in prostate cancer. (link.springer.com) robot Cao H Rhie SK Genome Biology 2026-07-23 #chromatin #enhancer #prostate cancer #gene regulation #crispr
0 💬 0 Phase 2 Randomized Bivalent RSVpreF Maternal Vaccine Trial: Final Safety, Antibody Persistence and Efficacy. (academic.oup.com) robot Simoes EAF Gurtman AC Journal of Infectious Diseases 2026-07-23 #vaccination #rsv #immunogenicity #maternal #clinical trial
0 💬 0 Prognostic Value of Aspergillus-Specific T Cells in Invasive Pulmonary Aspergillosis Among Patients with Hematologic Malignancies. (academic.oup.com) robot Serris A Lanternier F Journal of Infectious Diseases 2026-07-23 #aspergillosis #immunity #hematologic malignancy #immunoassay #prognosis
0 💬 0 Effects of Cyperus rotundus root exudates on Ralstonia solanacearum and Bacillus velezensis in relation to tobacco bacterial wilt occurrence. (journals.asm.org) robot Wu H He Y Microbiology Spectrum 2026-07-23 #microbiome #rhizosphere #pathogenesis #metagenomics #biofilm
0 💬 0 Programmable design of synthetic plant immune receptors for pathogen protein recognition. (science.org) robot Zhu H Gao C Science 2026-07-23 #immunity #pathogen #protein design #amr #synthetic biology
0 💬 0 Functional muscle networks as biomarkers of post-stroke motor impairment and therapeutic responsiveness. (elifesciences.org) robot O'Reilly D Severini G eLife 2026-07-23 #stroke #rehabilitation #biomarker #motor control #network analysis
0 💬 0 Trifluoperazine exhibits broad-spectrum antiviral activity against arboviruses. (journals.asm.org) robot Mishra L Kalia M Antimicrobial Agents and Chemotherapy 2026-07-23 #antiviral #arbovirus #dengue #drug-repurposing #stress response
0 💬 0 Repression of productive viral replication by KSHV LANA correlates with reduced adaptive immune activation: potential implications for KSHV immune evasion. (journals.asm.org) robot Murdock SJ Forrest JC mBio 2026-07-23 #immunity #herpesvirus #latency #evasion #replication
0 💬 0 Single-cell multiomics connects 3D genome and transcriptome alterations in Alzheimer's disease. (science.org) robot Zhang Y Ma J Science 2026-07-23 #multi-omics #chromatin #neurodegeneration #transcriptomics
0 💬 0 Crush-resistant air sacs allow insect larvae to exploit aquatic habitats at extreme depth. (science.org) robot McKenzie EKG Matthews PGD Science 2026-07-23 #adaptation #physiology #aquatic #insects
0 💬 0 Structural and mechanistic basis for membrane recognition and activation of the vacuolar lipase Atg15. (pnas.org) robot Kawamata T Sakai Y PNAS 2026-07-23 #autophagy #proteolysis #membrane-dynamics #simulation #enzyme-activation
0 💬 0 Time-resolved mapping in calves reveals bovine herpesvirus 1 shift from mucosal replication to trigeminal ganglion neuroinvasion with promyelocytic leukemia protein-centered host-virus antagonism. (journals.asm.org) robot Wang Y Li Y Microbiology Spectrum 2026-07-23 #neuroinvasion #herpesvirus #transcriptomics #pathogenesis #immunity
0 💬 0 Ex vivo pretreatment with venetoclax boosts the antileukemic efficacy of therapeutic gammadelta T cells in AML models. (jci.org) robot Chen X Zhu X Journal of Clinical Investigation 2026-07-23 #immunotherapy #leukemia #cytotoxicity #metabolism
0 💬 0 Palmitic acid coordinates impaired visceral adipose ICOShi Treg-mediated immunosuppression and systemic metabolic disturbance during obesity. (jci.org) robot Su W Li Y Journal of Clinical Investigation 2026-07-23 #immunity #obesity #inflammation #metabolism #immunosuppression
0 💬 0 Difficult-to-treat resistant Gram-negative bacteria and genomic resemblances between colonization and infection among patients in an intensive care unit of a tertiary care hospital in Bangladesh. (journals.asm.org) robot Mamun GMS Chowdhury F Microbiology Spectrum 2026-07-23 #amr #whole-genome sequencing #nosocomial-infection #colonization #gram-negative bacteria
0 💬 0 Single-cell multiomics and chromatin structure reveal gene-regulatory dynamics in heart failure. (science.org) robot Xie Y Chi NC Science 2026-07-23 #multi-omics #chromatin #heart failure #single-cell #transcriptomics
0 💬 0 TBC1D9 and TBC1D9B are ARL8 effectors that modulate exosome secretion through a RAB11A-exocyst pathway. (pnas.org) robot Shelke GV Bonifacino JS PNAS 2026-07-23 #exosome #endocytosis #vesicle trafficking #gtpase-signaling #membrane fusion
0 💬 0 Extension of penA diversity within the genus Neisseria: characterization of a penA/ftsI homolog in Neisseria bacilliformis associated with elevated ceftriaxone MICs. (journals.asm.org) robot Manoharan-Basil SS Kenyon C Antimicrobial Agents and Chemotherapy 2026-07-23 #amr #penicillin-binding proteins #neisseria #antibiotic #genomics
0 💬 0 A 3D genome atlas of human tonsil and the role of loop extrusion in B cell somatic hypermutation. (science.org) robot Cheng Y Wang S Science 2026-07-23 #immunity #somatic hypermutation #transcriptomics #chromatin #lymphocyte
0 💬 0 PRISM: Prior-enhanced Inference for Spatial Transcriptomic Cell Type Mapping. (academic.oup.com) robot Xu Y Li XM Bioinformatics 2026-07-23 #transcriptomics #annotation #spatial-transcriptomics #machine learning
0 💬 0 Mobile genetic elements-driven partitions of mega-plasmids resistome in Salmonella Infantis. (journals.asm.org) robot Zhang Y Wu VCH Microbiology Spectrum 2026-07-23 #amr #plasmids #horizontal transfer #genomics
0 💬 0 sept-1/zina-1 is an ancient toxin-antidote system in Caenorhabditis elegans. (journals.plos.org) robot Liu D Zheng C PLOS Biology 2026-07-23 #evolution #genetics #reproduction
0 💬 0 PAX5 modulates vascularization and contributes to neuroendocrine lineage transition during carcinoma progression. (jci.org) robot Wu A Liu Z Journal of Clinical Investigation 2026-07-23 #cancer #neuroendocrine #lineage #angiogenesis #plasticity
0 💬 0 Genetic background shapes the transcriptional activity and phenotypic contribution of a horizontally acquired region in yeast. (academic.oup.com) robot Romero A Salinas F Molecular Biology and Evolution 2026-07-23 #transcriptomics #horizontal transfer #quantitative trait loci #adaptation #oxidative stress
0 💬 0 Sentinel plants enable quantitative monitoring of bioavailable nitrate in soils and microbial environments. (pnas.org) robot Li E Demirer GS PNAS 2026-07-23 #biosensor #nitrogen #microbiome #soil #synthetic biology
0 💬 0 Global StationaryOT: Trajectory inference for aging time courses of single-cell snapshots. (academic.oup.com) robot Boyle C Schiebinger G Bioinformatics 2026-07-23 #single-cell #transcriptomics #trajectory #aging #differentiation
0 💬 0 The quantum ensemble variational optimization algorithm: Applications to molecular inverse design. (pnas.org) robot Calcagno F Batista VS PNAS 2026-07-23 #drug design #quantum computing #molecular-optimization #computational chemistry
0 💬 0 Longitudinal surveillance of antibiotic resistance and virulence evolution in Clostridioides difficile: a 4-year retrospective study of hospitalized patients in a tertiary hospital in China. (journals.asm.org) robot Lao J Wang X Microbiology Spectrum 2026-07-23 #amr #sequencing #virulence #surveillance #infection
0 💬 0 Birdsong diversity across the world. (science.org) robot Briefer EF Science 2026-07-23 #evolution #behavior #ecology
0 💬 0 Spatially resolved single-cell atlas reveals the macroevolutionary trajectory of animal hearts. (science.org) robot Lian S Zhao L Science 2026-07-23 #transcriptomics #evolution #cardiology #comparative #cell-type
0 💬 0 Parasites constrain within-population diversification while accelerating between-population divergence in an RNA replication system. (academic.oup.com) robot Kanai Y Ichihashi N Molecular Biology and Evolution 2026-07-23 #evolution #rna #parasite #diversification #selection
0 💬 0 Partitioning of the truncated insulin receptor DAF-2B between homodimers and heterodimers influences insulin signaling in C. elegans. (journals.plos.org) robot Martinez BA Gill MS PLOS Genetics 2026-07-23 #signaling #insulin #receptor #longevity #neuropeptide
0 💬 0 Epigenetic and 3D genome reprogramming during the aging of the human hippocampus. (science.org) robot Zemke NR Ren B Science 2026-07-23 #epigenetics #aging #neurodegeneration #chromatin #transcriptomics
0 💬 0 EscaPRRS-ORF5: A Structure-Aware Evolutionary Framework for Prioritizing Immune Escape-Prone Variants in Porcine Reproductive and Respiratory Syndrome Virus. (academic.oup.com) robot S R V Chowdhury R Bioinformatics 2026-07-23 #virulence #evolution #immunity #vaccination #prediction