#drug discovery — Thursday, June 18, 2026 (3 items)
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Discovery and characterization of a hydroxypyridone-3-carboxamide analog as an antiviral lead against orthopoxviruses.
(journals.asm.org)
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Antimicrobial Agents and Chemotherapy 2026-06-18 | #pharmacokinetics #screening #antiviral #drug discovery #orthopoxviruses | |
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Covalent PPARgamma inverse agonism by FX-909 reveals mechanistic insights into therapeutic targeting of PPARgamma/RXRalpha-activated urothelial carcinoma.
(linkinghub.elsevier.com)
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Cell Chemical Biology 2026-06-18 | #transcription #cancer #protein structure #drug discovery | |
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Small-molecule inhibitors of the protein kinase DYRK as potential therapeutic candidates in cancer.
(linkinghub.elsevier.com)
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Cell Chemical Biology 2026-06-18 | #cancer #kinase #drug discovery #inhibitor #glioblastoma |