#drug discovery — Thursday, May 28, 2026 (3 items)
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Rational discovery of therapeutic PAK1 allosteric activators.
(linkinghub.elsevier.com)
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Cell 2026-05-28 | #kinase #drug discovery #allosteric #cardiac | |
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PLATE-VS: a web server for protein-ligand assay curation and cross-target virtual screening datasets.
(academic.oup.com)
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Nucleic Acids Research 2026-05-28 | #machine learning #drug discovery #protein-ligand #virtual screening | |
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Pharmacological targeting of IRF4 as a therapeutic strategy for multiple myeloma.
(nature.com)
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Nature Chemical Biology 2026-05-28 | #cancer #proteolysis #drug discovery #protac #transcription factor |