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#crispr — Friday, May 01, 2026 (11 items)

0 💬 0 Exapted CRISPR-Cas12f homologues drive RNA-guided transcription. (nature.com) robot Hoffmann FT Sternberg SH Nature 2026-05-01 #transcription #crispr #gene regulation #protein-protein interaction #rna-guided
0 💬 0 Molecular basis for methylation-sensitive editing by Cas9. (nature.com) robot Roth MO Li H Nature 2026-05-01 #methylation #cancer #crispr #genome editing
0 💬 0 Structural basis of supercoiling-induced CRISPR-Cas9 off-target activity. (nature.com) robot Smith QM Rueda DS Nature 2026-05-01 #cryo-em #crispr #genome editing #off-target
0 💬 0 A leader-repeat hairpin blocks extraneous CRISPR RNA production in diverse CRISPR-Cas13 systems. (link.springer.com) robot Migur A Beisel CL The EMBO Journal 2026-05-01 #immunity #rna #crispr #regulation #phage
0 💬 0 Modular engineering of thermoresponsive allosteric proteins. (nature.com) robot Kroell AS Mathony J Nature Chemical Biology 2026-05-01 #crispr #synthetic biology #protein design #allosteric #thermogenetics
0 💬 0 Targeting ubiquitin signaling vulnerabilities in KEAP1-inactivated lung cancer. (link.springer.com) robot Shah VJ Dikic I The EMBO Journal 2026-05-01 #metabolism #cancer #crispr #proteostasis #ubiquitin
0 💬 0 Mechanistic basis for selective Csm6-2 activation by cyclic penta-adenylate in a type III CRISPR-Cas system. (link.springer.com) robot Shi R Lin Z The EMBO Journal 2026-05-01 #immunity #crispr #ribonuclease #viral defense
0 💬 0 DNA-guided CRISPR-Cas12a effectors for programmable RNA recognition and cleavage. (nature.com) robot Wu X Hsing IM Nature Biotechnology 2026-05-01 #rna #crispr #genome editing #nuclease
0 💬 0 CRISPR-Cas9 CD33-deleted allogeneic hematopoietic cell transplantation with gemtuzumab ozogamicin maintenance in AML: a phase 1/2 trial. (nature.com) robot DiPersio JF Cooper BW Nature Medicine 2026-05-01 #immunotherapy #crispr #genome editing #aml #hematopoietic
0 💬 0 Systematic design of combination therapy by targeting master regulators of coexisting diffuse midline glioma cell states. (nature.com) robot Calvo Fernandez E Pavisic J Nature Genetics 2026-05-01 #transcriptomics #crispr #heterogeneity #combination therapy #glioma
0 💬 0 Structural basis of RNA-guided transcription by a dCas12f-sigma(E)-RNAP complex. (nature.com) robot Xiao R Chang L Nature 2026-05-01 #transcription #cryo-em #crispr #rna-guided #sigma factors