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#cancer — Tuesday, April 21, 2026 (26 items)

0 ℹ Impact of chronic low-dose external gamma- and internal tritium beta-irradiation on the gut microbiome in the context of intestinal tumorigenesis in Apc(Min/+) mice. (journals.asm.org) robot Laakso H … Klokov D mSystems 2026-04-21 #microbiome #dysbiosis #cancer #inflammation #sequencing
0 ℹ Type I interferons induced upon respiratory viral infection impair lung metastatic initiation. (pnas.org) robot Farias A … Johansson C PNAS 2026-04-21 #infection #immunity #cancer #metastasis #interferon
0 ℹ SpaNiche: spatial niche analysis to explore colocalization patterns and cellular interactions in spatial transcriptomics data. (link.springer.com) robot Huang S … Xi R Genome Biology 2026-04-21 #transcriptomics #cancer #clustering #interaction
0 ℹ WWOX maintains epidermal identity and suppresses EMT to prevent aggressive cutaneous squamous cell carcinoma. (pnas.org) robot Bidany-Mizrahi T … Aqeilan RI PNAS 2026-04-21 #virulence #transcriptomics #cancer #emt
0 ℹ Development and validation of a 5mC-based prognostic model for lung adenocarcinoma survival. (linkinghub.elsevier.com) robot Wu Y … Chen Q Cell Reports Medicine 2026-04-21 #modeling #methylation #cancer #biomarker #prognosis
0 ℹ Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature. (linkinghub.elsevier.com) robot Lobb RJ … Moller A Cell Reports Medicine 2026-04-21 #proteomics #cancer #biomarker #diagnostics #extracellular vesicles
0 ℹ The microbial metabolome: remodeling the therapeutic landscape in hematologic malignancies. (nature.com) robot Zhang L … Gafarov R npj Biofilms and Microbiomes 2026-04-21 #microbiome #metabolism #cancer #immunotherapy #chemotherapy
0 ℹ Immunogenic tumor cell death and T-cell-derived IFN-gamma elicit tumoricidal macrophages to potentiate OX40 immunotherapy. (linkinghub.elsevier.com) robot Liu Y … Zhang H Cell Reports Medicine 2026-04-21 #immunity #cancer #immunotherapy #macrophage #tumor microenvironment
0 ℹ Combination immunotherapy for colorectal cancer: Clinical applications, rationale, challenges, and future perspectives. (linkinghub.elsevier.com) robot Fei J … Zeng S Cell Reports Medicine 2026-04-21 #cancer #immunotherapy #biomarker #tme
0 ℹ A senescent tumor cell-derived nanovesicle directly primes splenic T cells to potentiate cancer radiotherapy. (linkinghub.elsevier.com) robot Pan J … Lai Y Cell Reports Medicine 2026-04-21 #immunity #cancer #immunotherapy #senescence #nanovesicles
0 ℹ Histone methyl-transferase G9a inhibition boosts the efficacy of immune checkpoint inhibitors in experimental hepatocellular carcinoma. (linkinghub.elsevier.com) robot Adan-Villaescusa E … Fernandez-Barrena MG Cell Reports Medicine 2026-04-21 #immunity #cancer #epigenetics #immunotherapy #hepatocellular carcinoma
0 ℹ A harmless-to-harmful switchable and spatiotemporally activated nano-CRISPR hierarchically amplifies ferroptosis in melanoma. (linkinghub.elsevier.com) robot Ou C … Gong C Cell Reports Medicine 2026-04-21 #nanoparticles #cancer #crispr #ferroptosis #ros
0 ℹ Single-cell analysis highlights the significance of malignant cell IFN/MHC-II for immunotherapy response in head and neck squamous cell carcinoma. (linkinghub.elsevier.com) robot Mints M … Puram SV Cell Reports Medicine 2026-04-21 #immunity #transcriptomics #cancer #immunotherapy #biomarker
0 ℹ Robust transcriptomic hallmarks targeting intratumor heterogeneity in intrahepatic cholangiocarcinoma. (linkinghub.elsevier.com) robot Lin Y … Fan J Cell Reports Medicine 2026-04-21 #transcriptomics #cancer #immunotherapy #biomarker #heterogeneity
0 ℹ HE4 drives PD-L1 expression in myeloid cells via IFN-gammaR-JAK-STAT3 signaling to promote tumor immune evasion. (linkinghub.elsevier.com) robot Zeng B … Wang C Cell Reports Medicine 2026-04-21 #cancer #immunotherapy #signaling #biomarker #checkpoint
0 ℹ Targeting TPX2-dependent lineage plasticity by CDK4/6 inhibition reverses therapy resistance in neuroendocrine bladder carcinoma. (linkinghub.elsevier.com) robot Chen Z … Chen X Cell Reports Medicine 2026-04-21 #immunity #transcriptomics #cancer #plasticity
0 ℹ A bispecific nanobody-drug conjugate targeting TROP2 and c-Met for low-concentration, single-dose treatment of pancreatic cancer. (linkinghub.elsevier.com) robot Ning W … Luo W Cell Reports Medicine 2026-04-21 #antibody #cancer #immunotherapy #therapeutics #cytotoxicity
0 ℹ mRNA lipid-nanoparticle-mediated mitochondrial apoptosis augments adoptive T cell immunotherapy. (linkinghub.elsevier.com) robot Fu J … Jin Y Cell Reports Medicine 2026-04-21 #transcriptomics #cancer #immunotherapy #rna #apoptosis
0 ℹ Single-cell spatial transcriptomics reveals tumor microenvironment heterogeneity in primary and lymph node-metastatic small cell lung cancer. (linkinghub.elsevier.com) robot Zhang Z … Zhou M Cell Reports Medicine 2026-04-21 #immunity #transcriptomics #cancer #microenvironment
0 ℹ Self-adjuvanting alpha-helical polypeptide simultaneously delivers neoantigen mRNAs and activates dendritic cells to eradicate tumors. (pnas.org) robot Han J … Wang H PNAS 2026-04-21 #vaccination #cancer #immunotherapy #neoantigen #dendritic cell
0 ℹ Profile of Helen M. Piwnica-Worms. (pnas.org) robot Williams SCP PNAS 2026-04-21 #modeling #amr #cancer #cell cycle
0 ℹ Targeting the ferritinophagy-lysosome axis as a therapeutic vulnerability in gastroenteropancreatic neuroendocrine tumors. (linkinghub.elsevier.com) robot Cao Y … Qiao Y Cell Reports Medicine 2026-04-21 #amr #metabolism #cancer #autophagy #lysosome
0 ℹ Out-of-frame CBX3::ALK fusion drives ALK activation and therapy response. (linkinghub.elsevier.com) robot Hang JF … Yang MH Cell Reports Medicine 2026-04-21 #cancer #sequencing #kinase #fusion #oncology
0 ℹ Engineered oncolytic virus armed with anti-PCSK9 scFv boosts long-term CD8(+) T cell immunity via rewiring MHC-I antigen presentation. (linkinghub.elsevier.com) robot Feng H … Xing F Cell Reports Medicine 2026-04-21 #immunity #cancer #immunotherapy #engineering #oncolytic
0 ℹ Spatial multi-omics unveils the monoclonal origin, neuroendocrine plasticity, and microenvironment niches in combined small-cell lung cancer. (linkinghub.elsevier.com) robot Wang Z … Li Z Cell Reports Medicine 2026-04-21 #cancer #microenvironment #heterogeneity #plasticity #spatial omics
0 ℹ Targeting the noncanonical function of metabolic enzyme PHGDH in driving PD-L1 expression and cancer immune evasion. (linkinghub.elsevier.com) robot Liu J … Feng Z Cell Reports Medicine 2026-04-21 #metabolism #immunity #cancer #signaling